2026
article
OpenAlex
Mahmoud Alwakeel, Mohammed Akbar, Armando Bedoya, Karthik Raghunathan et autres
us
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2026
article
OpenAlex
Noah J. Timko, Mary Cooter Wright, Melody R. Smith, Piper C. Boykin et autres
Importance: The apolipoprotein E (APOE) gene ε4 allele leads to increased Alzheimer disease risk and neuroinflammation and is also believed to play a role in postoperative delirium. However, the safety and feasibility of modulating apoE protein signaling to reduce postoperative neuroinflammation and …
us, gb, se, cn, fr, gr
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2025
article
OpenAlex
Julie M. Steinbrink, Nitin Mehdiratta, Heather Pena, Ian J. Welsby et autres
OBJECTIVE: Diagnostic stewardship of blood culture utilization is important to mitigate the risks associated with unnecessary culturing. Although blood culture algorithms have been studied previously, there is a lack of data on their application among solid organ transplant (SOT) recipients. This study …
us
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2025
article
OpenAlex
Ronald M. Harris, Morgan Rosser, Vijay Krishnamoorthy, Nitin Mehdiratta et autres
il, us
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2025
article
OpenAlex
Nitin Mehdiratta, Erin Gettler, Vijay Krishnamoorthy, Kathleen Claus et autres
Objective To evaluate the implementation of a blood culture algorithm in a mixed medical-surgical ICU at a community hospital, and examine the association with blood culture utilization rate and patient outcomes. Design: A quasi-experimental study examining pre- and post-implementation periods. Setting: A …
us
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2025
article
OpenAlex
Julie M. Steinbrink, Nitin Mehdiratta, Heather Pena, Ian J. Welsby et autres
Abstract Background Diagnostic stewardship of blood culture utilization is paramount to mitigate the risks associated with excessive culturing, including increased contamination rates and inappropriate antimicrobial administration. Although blood culture algorithms have been studied previously, there is insufficient data on their application specifically …
us
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2024
article
OpenAlex
Ronald M. Harris, Nitin Mehdiratta, Morgan Rosser, Anand M. Chowdhury et autres
BACKGROUND: Central Line Associated Blood Stream Infections (CLABSI) are significant complications for hospitalized patients. Several different approaches have been used to reduce CLABSI. OBJECTIVE: This study aimed to (1) describe a systematic approach used to analyze and reduce CLABSI rates in a …
us
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2023
article
OpenAlex
Jessica Seidelman, Rebekah W. Moehring, Erin Gettler, Jay Krishnan et autres
Abstract Objective: We compared the number of blood-culture events before and after the introduction of a blood-culture algorithm and provider feedback. Secondary objectives were the comparison of blood-culture positivity and negative safety signals before and after the intervention. Design: Prospective cohort design. …
us
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2023
article
OpenAlex
Rodrigo O. L. Pereira, Tetsu Ohnuma, Nitin Mehdiratta, Nazish Hashmi et autres
The critical care medicine (CCM) fellowship is an opportunity for advanced anesthesiology trainees to refine their quality improvement (QI) skills. However, the short training period and inconsistent curricula make this challenging. The QI fellow (QIF) is described as an education program to …
us
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2023
article
OpenAlex
Ronald M. Harris, M Rosser, Nitin Mehdiratta, Anand Chowdhurry et autres
Central Line Associated Blood Stream Infections (CLABSI) continue to be a significant complication for hospitalized patients. Hospitals have used various strategies to reduce CLABSI events due to the significant complications and associated costs. In this QI analysis, we examined the impact of …
us
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2023
article
OpenAlex
Jessica Seidelman, Rebekah W. Moehring, Erin Gettler, Jay Krishnan et autres
Background: Blood cultures are commonly ordered for patients with low risk of bacteremia. Liberal blood-culture ordering increases the risk of false-positive results, which can lead to increased length of stay, excess antibiotics, and unnecessary diagnostic procedures. We implemented a blood-culture indication algorithm …
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2020
article
OpenAlex
Kimberly F. Rengel, Nitin Mehdiratta, Susan Vanston, Kristin R. Archer et autres
us
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