Yang Yu

Representative R Code for: Development and External Validation of a Machine Learning Model for Predicting Liver Injury in Children With Mycoplasma Pneumoniae Pneumonia

Hongjuan Wei, Yang Yu, Yang Jing, Yinyan Tang et autres

This repository contains a representative R implementation of the analyticalpipeline described in the Methods section of the associated manuscript"Development and External Validation of a Machine Learning Model forPredicting Liver Injury in Children With Mycoplasma Pneumoniae Pneumonia"(Yu, Jing, Tang, Liu, Wei; Scientific Reports, …

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Representative R Code for: Development and External Validation of a Machine Learning Model for Predicting Liver Injury in Children With Mycoplasma Pneumoniae Pneumonia

Hongjuan Wei, Yang Yu, Yang Jing, Yinyan Tang et autres

This repository contains a representative R implementation of the analyticalpipeline described in the Methods section of the associated manuscript"Development and External Validation of a Machine Learning Model forPredicting Liver Injury in Children With Mycoplasma Pneumoniae Pneumonia"(Yu, Jing, Tang, Liu, Wei; Scientific Reports, …

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Application of Clinical Indicators in the Early Prediction of Refractory Mycoplasma pneumoniae Pneumonia in Children: A Retrospective Study

Yang Yu, Rufeng Ji, Yu Xia

This study aims to compare the clinical characteristics of children with general Mycoplasma pneumoniae pneumonia (GMPP) and refractory Mycoplasma pneumoniae pneumonia (RMPP), identify predictive factors for RMPP, and construct a predictive nomogram for early clinical prediction of RMPP. This retrospective study included …

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Establishment of a TaqMan qPCR assay for the rapid detection and quantification of Nocardia seriolae in aquaculture

Zexia Chen, Yang Yu, Tiansheng Zhu, Chaowei Song et autres

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Molecular identification of somatostatin family in tilapia and the effect of food intake on pss2 and sstr3a

Ran Cai, Jiahui Zhang, Xiaozheng Yu, Yang Yu et autres

Somatostatin (SS) plays an important role in regulating food intake and following digestive functions of vertebrates mediated via somatostatin receptor (SSTR). However, the feedback regulation by which food intake regulate SS and SSTRs expression, and thereby their functions, remains poorly understood. Here, …

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Screening and identification of host signaling pathways for alleviating influenza-induced production of pro-inflammatory cytokines, IP-10, IL-8, and MCP-1, using a U937 cell-based influenza model

Si Chen, Yang Yu, Yue Su, Xiaoqin Lian et autres

Influenza virus infection initiates an exaggerated inflammatory response, which may culminate in a fatal cytokine storm characterized by the excessive production of pro-inflammatory cytokines. Prior research indicates that IP-10, IL-8, and MCP-1, primarily produced by monocytes and macrophages, play a crucial role …

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How to Select Equilibrium Selection Devices from Data?

Yang Yu

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Multi-transcriptomics analysis of microvascular invasion-related malignant cells and development of a machine learning-based prognostic model in hepatocellular carcinoma

Haoran Huang, Feifeng Wu, Yang Yu, Borui Xu et autres

Background: Microvascular invasion (MVI) stands as a pivotal pathological hallmark of hepatocellular carcinoma (HCC), closely linked to unfavorable prognosis, early recurrence, and metastatic progression. However, the precise mechanistic underpinnings governing its onset and advancement remain elusive. Methods: In this research, we downloaded …

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Effect of GLP-1 receptor agonist on cardiac remodelling: a systematic review and meta-analysis

Yang Yu, xiao ru huang, pan hui tian

Participant or populationPatients with left ventricular ejection fraction ≥ 50% with or without type 2 diabetes.Intervention Use GLP-1RAs.

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Unusual presentation of PD-1 inhibitors in people living with HIV with advanced gastric cancer: Case report

Zhidi Gao, Guangyong XU, Su Wang, Na Guo et autres

This paper seeks to determine the effect of combination anti-PD-1 and antiretroviral therapy (ART) on people living with HIV (PLWH) with advanced gastric cancer. In our case, a PLWH with recurrent locally advanced gastric cancer was treated with anti-PD-1 inhibitor and ART. …

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A panel of janus kinase inhibitors identified with anti-inflammatory effects protect mice from lethal influenza virus infection

Yang Yu, Si Chen, Haonan Zhang, Yuanyuan Duan et autres

ABSTRACT Influenza remains a significant threat to public health. In severe cases, excessive inflammation can lead to severe pneumonia or acute respiratory distress syndrome, contributing to patient morbidity and mortality. While antivirals can be effective if administered early, current anti-inflammatory drugs have …

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Evaluating the performance of ChatGPT in clinical pharmacy: A comparative study of ChatGPT and clinical pharmacists

Xiaoru Huang, Dannya Estau, Xuening Liu, Yang Yu et autres

AIMS: To evaluate the performance of chat generative pretrained transformer (ChatGPT) in key domains of clinical pharmacy practice, including prescription review, patient medication education, adverse drug reaction (ADR) recognition, ADR causality assessment and drug counselling. METHODS: Questions and clinical pharmacist's answers were …

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