ND Palmer

Genome-wide gene-environment interaction analysis identifies genetic signals associated with cardiometabolic phenotypes and physical activity in Hispanic Americans: The Insulin Resistance Atherosclerosis Family Study (IRASFS); (Abstract/Program #649)

ND Palmer, Hsin CHI, C GAO, DW BOWDEN et autres

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.

International Consortium for Blood Pressure Genome-Wide Associat, GB Ehret, PB Munroe, K M Rice et autres

Blood pressure is a heritable trait influenced by several biological pathways and responsive to environmental stimuli. Over one billion people worldwide have hypertension (≥140 mm Hg systolic blood pressure or ≥90 mm Hg diastolic blood pressure). Even small increments in blood pressure …

054 Plaque vulnerability is an important feature of chronic stable coronary disease: a comparison of lesion characteristics in stable angina and acute coronary syndrome patients using virtual histology

S W Murray, Rod Stables, George W. Hart, R A Perry et autres

Introduction Rupture of a vulnerable plaque is the most important mechanism leading to acute coronary syndromes (ACS). Studies have shown that the most common feature of these plaques is the presence of a thin-cap fibroatheroma (TCFA). Previous studies have also shown the …

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Exostosin 2: A Replicated Quantitative Trait Locus for Insulin Clearance.

MO Goodarzi, ND Palmer, D Stefanovski, KD Taylor et autres

Intermediate and high peri-operative cardiac enzyme release following isolated coronary artery bypass surgery are independently associated with higher one-year mortality

Nick Newall, AY Oo, ND Palmer, Antony D. Grayson et autres

BACKGROUND: The relationship between cardiac enzyme (CE) release following coronary artery bypass surgery (CABG) and medium term outcome is unclear. We sought to determine the relationship between post-operative CE release and one-year survival following isolated CABG. METHODS: Over three years 3,024 consecutive …

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In-hospital resource utilization in coronary angioplasty: the impact of increased coronary stenting rates and antiplatelet therapy

ND Palmer, Stephen Fort, I R Starkey, TRD Shaw et autres

BACKGROUND: The technique of coronary stenting has evolved over recent years, with improved stent technology and effective antiplatelet therapies to prevent stent thrombosis. In Europe, reductions in stent and equipment costs have resulted from increased market competition. The impact of these changes …

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