Rachel T. Palmieri

Data from Genetic Variation in TYMS in the One-Carbon Transfer Pathway Is Associated with Ovarian Carcinoma Types in the Ovarian Cancer Association Consortium

Linda E. Kelemen, Marc T. Goodman, Valerie McGuire, Mary Anne Rossing et autres

Abstract Background: We previously reported the risks of ovarian carcinoma for common polymorphisms in one-carbon transfer genes. We sought to replicate associations for DPYD rs1801265, DNMT3A rs13420827, MTHFD1 rs1950902, MTHFS rs17284990, and TYMS rs495139 with risk of ovarian carcinoma overall and to …

Supplementary Tables 1-2 from Genetic Variation in TYMS in the One-Carbon Transfer Pathway Is Associated with Ovarian Carcinoma Types in the Ovarian Cancer Association Consortium

Linda E. Kelemen, Marc T. Goodman, Valerie McGuire, Mary Anne Rossing et autres

Supplementary Tables 1-2 from Genetic Variation in TYMS in the One-Carbon Transfer Pathway Is Associated with Ovarian Carcinoma Types in the Ovarian Cancer Association Consortium

Data from Genetic Variation in TYMS in the One-Carbon Transfer Pathway Is Associated with Ovarian Carcinoma Types in the Ovarian Cancer Association Consortium

Linda E. Kelemen, Marc T. Goodman, Valerie McGuire, Mary Anne Rossing et autres

Abstract Background: We previously reported the risks of ovarian carcinoma for common polymorphisms in one-carbon transfer genes. We sought to replicate associations for DPYD rs1801265, DNMT3A rs13420827, MTHFD1 rs1950902, MTHFS rs17284990, and TYMS rs495139 with risk of ovarian carcinoma overall and to …

ca, us, au, de, gb, dk (code pays fourni par la source)

Supplementary Tables 1-2 from Genetic Variation in TYMS in the One-Carbon Transfer Pathway Is Associated with Ovarian Carcinoma Types in the Ovarian Cancer Association Consortium

Linda E. Kelemen, Marc T. Goodman, Valerie McGuire, Mary Anne Rossing et autres

Supplementary Tables 1-2 from Genetic Variation in TYMS in the One-Carbon Transfer Pathway Is Associated with Ovarian Carcinoma Types in the Ovarian Cancer Association Consortium

Supplementary Tables 1-4 from Ovarian Cancer Risk Associated with Inherited Inflammation-Related Variants

Kristin L. White, Joellen M. Schildkraut, Rachel T. Palmieri, Edwin S. Iversen et autres

PDF file - 114K

Supplementary Tables 1-4 from Ovarian Cancer Risk Associated with Inherited Inflammation-Related Variants

Kristin L. White, Joellen M. Schildkraut, Rachel T. Palmieri, Edwin S. Iversen et autres

PDF file - 114K

Data from Ovarian Cancer Risk Associated with Inherited Inflammation-Related Variants

Kristin L. White, Joellen M. Schildkraut, Rachel T. Palmieri, Edwin S. Iversen et autres

Abstract The importance of inflammation pathways to the development of many human cancers prompted us to examine the associations between single-nucleotide polymorphisms (SNP) in inflammation-related genes and risk of ovarian cancer. In a multisite case–control study, we genotyped SNPs in a large …

Data from Ovarian Cancer Risk Associated with Inherited Inflammation-Related Variants

Kristin L. White, Joellen M. Schildkraut, Rachel T. Palmieri, Edwin S. Iversen et autres

Abstract The importance of inflammation pathways to the development of many human cancers prompted us to examine the associations between single-nucleotide polymorphisms (SNP) in inflammation-related genes and risk of ovarian cancer. In a multisite case–control study, we genotyped SNPs in a large …

Pooled analysis of the association of PTGS2 rs5275 polymorphism and NSAID use with invasive ovarian carcinoma risk

Katharine McDuffie, Kathryn L. Terry, Galina Lurie, Marc T. Goodman et autres

Inflammation is postulated to play an important role in ovarian carcinogenesis. Prostaglandin endoperoxide synthase 2 (PTGS2) is responsible for the conversion of arachidonic acid to prostaglandins in response to inflammation. We examined the association of the PTGS2 rs5275 polymorphism with the risk …

us (code pays fourni par la source)

Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case–control studies

Kara L. Cushing‐Haugen, Celeste Leigh Pearce, Jennifer A. Doherty, Hoda Anton‐Culver et autres

Endometriosis is a risk factor for epithelial ovarian cancer; however, whether this risk extends to all invasive histological subtypes or borderline tumours is not clear. We undertook an international collaborative study to assess the association between endometriosis and histological subtypes of ovarian …

Association between DNA Damage Response and Repair Genes and Risk of Invasive Serous Ovarian Cancer

Regina S. Whitaker, Merlise A. Clyde, Joellen M. Schildkraut, Melanie A. Wilson et autres

BackgroundWe analyzed the association between 53 genes related to DNA repair and p53-mediated damage response and serous ovarian cancer risk using case-control data from the North Carolina Ovarian Cancer Study (NCOCS), a population-based, case-control study.Methods/Principal FindingsThe analysis was restricted to 364 invasive …

Consumer product exposures associated with urinary phthalate levels in pregnant women

Amy H. Herring, Jeanine M Matuszewski, Jessie P. Buckley, Jane A. Hoppin et autres

Human phthalate exposure is ubiquitous, but little is known regarding predictors of urinary phthalate levels. To explore this, 50 pregnant women aged 18–38 years completed two questionnaires on potential phthalate exposures and provided a first morning void. Urine samples were analyzed for …