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Daniel R. Zerbino, Nathan Johnson, Thomas Juetteman, Dan Sheppard et autres
New experimental techniques in epigenomics allow researchers to assay a diversity of highly dynamic features such as histone marks, DNA modifications or chromatin structure. The study of their fluctuations should provide insights into gene expression regulation, cell differentiation and disease. The Ensembl …
gb (code pays fourni par la source)
Paul Flicek, M Ridwan Amode, Daniel G. Barrell, Kathryn M. Beal et autres
Ensembl (http://www.ensembl.org) creates tools and data resources to facilitate genomic analysis in chordate species with an emphasis on human, major vertebrate model organisms and farm animals. Over the past year we have increased the number of species that we support to 77 …
gb (code pays fourni par la source)
Paul Flicek, Ikhlak Ahmed, M Ridwan Amode, Daniel G. Barrell et autres
The Ensembl project (http://www.ensembl.org) provides genome information for sequenced chordate genomes with a particular focus on human, mouse, zebrafish and rat. Our resources include evidenced-based gene sets for all supported species; large-scale whole genome multiple species alignments across vertebrates and clade-specific alignments …
gb (code pays fourni par la source)
Paul Flicek, M Ridwan Amode, Daniel G. Barrell, Kathryn M. Beal et autres
The Ensembl project (http://www.ensembl.org) provides genome resources for chordate genomes with a particular focus on human genome data as well as data for key model organisms such as mouse, rat and zebrafish. Five additional species were added in the last year including …
gb (code pays fourni par la source)
Paul Flicek, M Ridwan Amode, Daniel G. Barrell, Kathryn M. Beal et autres
The Ensembl project (http://www.ensembl.org) seeks to enable genomic science by providing high quality, integrated annotation on chordate and selected eukaryotic genomes within a consistent and accessible infrastructure. All supported species include comprehensive, evidence-based gene annotations and a selected set of genomes includes …
gb (code pays fourni par la source)
William M. McLaren, Bethan L. Pritchard, Daniel Ríos, Yuan Chen et autres
Abstract Summary: A tool to predict the effect that newly discovered genomic variants have on known transcripts is indispensible in prioritizing and categorizing such variants. In Ensembl, a web-based tool (the SNP Effect Predictor) and API interface can now functionally annotate variants …
gb (code pays fourni par la source)
Anne Parker, Eugene Bragin, Simon Brent, Bethan L. Pritchard et autres
BACKGROUND: The Ensembl web site has provided access to genomic information for almost 10 years. During this time the amount of data available through Ensembl has grown dramatically. At the same time, the World Wide Web itself has become a dramatically more …
gb (code pays fourni par la source)
Yuan Chen, Fiona M Cunningham, Daniel Ríos, William M. McLaren et autres
BACKGROUND: The maturing field of genomics is rapidly increasing the number of sequenced genomes and producing more information from those previously sequenced. Much of this additional information is variation data derived from sampling multiple individuals of a given species with the goal …
gb (code pays fourni par la source)
Paul Flicek, Bronwen L. Aken, Benoît Ballester, Kathryn M. Beal et autres
Ensembl (http://www.ensembl.org) integrates genomic information for a comprehensive set of chordate genomes with a particular focus on resources for human, mouse, rat, zebrafish and other high-value sequenced genomes. We provide complete gene annotations for all supported species in addition to specific resources …
gb (code pays fourni par la source)
Matthew J. Nicholson, Albert Koulman, Brendon J. Monahan, Bethan L. Pritchard et autres
Aflatrem is a potent tremorgenic toxin produced by the soil fungus Aspergillus flavus, and a member of a structurally diverse group of fungal secondary metabolites known as indole-diterpenes. Gene clusters for indole-diterpene biosynthesis have recently been described in several species of filamentous …
nz, us (code pays fourni par la source)
Tim Hubbard, Bronwen L. Aken, Sarah Ayling, Benoît Ballester et autres
The Ensembl project (http://www.ensembl.org) is a comprehensive genome information system featuring an integrated set of genome annotation, databases, and other information for chordate, selected model organism and disease vector genomes. As of release 51 (November 2008), Ensembl fully supports 45 species, and …
gb (code pays fourni par la source)
Michael S. Price, Jiujiang Yu, William C. Nierman, Heenam Stanley Kim et autres
Aflatoxin contamination of food and feed is a major concern due to the carcinogenic properties of this mycotoxin. Previous studies using classical approaches have identified a cluster of genes responsible for aflatoxin production under the control of the pathway-specific transcriptional regulator aflR, …
us (code pays fourni par la source)
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