Fernando G. Cosio

Extreme phenotype sampling and next generation sequencing to identify genetic variants associated with tacrolimus in African American kidney transplant recipients

Moataz E. Mohamed, Bin Guo, Baolin Wu, David P. Schladt et autres

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Corrigendum to Heybeli C, Bentall A, Wen J, et al. A study from The Mayo Clinic evaluated long-term outcomes of kidney transplantation in patients with immunoglobulin light chain amyloidosis. Kidney Int. 2021;99:707–715

Cihan Heybeli, Andrew Bentall, Jiqiu Wen, Mariam P. Alexander et autres

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Impact of Pregnancy on GFR Decline and Kidney Histology in Kidney Transplant Recipients

Andrea G. Kattah, Sam Albadri, Mariam P. Alexander, Byron H. Smith et autres

Introduction Women with advanced kidney disease are advised to wait until after transplant to pursue pregnancy, but the impact of pregnancy on estimated glomerular filtration rate (eGFR) decline and kidney histology is unclear. Methods We identified a cohort of women aged 18 …

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Pregnancy, Contraception, and Menopause in Advanced Chronic Kidney Disease and Kidney Transplant

Virginia Dines, Vesna D. Garovic, Santosh Parashuram, Fernando G. Cosio et autres

Background: Reproductive health is an essential part of the care of women with kidney disease. However, the self-reported patient experience of reproductive issues has been underexplored. Materials and Methods: We identified a cohort of women ages 18 to 44 at the time …

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i-IFTA and chronic active T cell–mediated rejection: A tale of 2 (DeKAF) cohorts

Erika S. Helgeson, Roslyn B. Mannon, Joseph P. Grande, Robert S. Gaston et autres

Inflammation in areas of fibrosis (i-IFTA) in posttransplant biopsies is part of the diagnostic criteria for chronic active TCMR (CA TCMR -- i-IFTA ≥ 2, ti ≥ 2, t ≥ 2). We evaluated i-IFTA and CA TCMR in the DeKAF indication biopsy …

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Long-term Outcomes of Sequential Hematopoietic Stem Cell Transplantation and Kidney Transplantation: Single-center Experience

Carla Moreira, M Hasib Sidiqi, Francis K. Buadi, Mark R. Litzow et autres

BACKGROUND: Experience with sequential hematopoietic stem cell transplant (HSCT) and kidney transplant (KT) is limited. METHODS: We conducted a retrospective observational study of adult patients who underwent both HSCT and KT at our center, with a median follow-up of 11 y. RESULTS: …

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Reproductive Health in Kidney Transplant Recipients

Andrea G. Kattah, Fernando G. Cosio, Vesna D. Garovic

Background: Women with advanced chronic kidney disease develop menstrual irregularities and infertility that can improve after kidney transplant. However, some women do not have menstrual cycles return after transplant and pregnancy rates are lower than in the general population, which could be …

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A study from The Mayo Clinic evaluated long-term outcomes of kidney transplantation in patients with immunoglobulin light chain amyloidosis

Cihan Heybeli, Andrew Bentall, Jiqiu Wen, Mariam P. Alexander et autres

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Recurrence of DNAJB9-Positive Fibrillary Glomerulonephritis After Kidney Transplantation: A Case Series

Mireille El Ters, Shane A. Bobart, Lynn D. Cornell, Nelson Leung et autres

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Competing Risk Analysis in Renal Allograft Survival: A New Perspective to an Old Problem

Mireille El Ters, Byron H. Smith, Fernando G. Cosio, Walter K. Kremers

BACKGROUND: Graft survival after kidney transplant (KTX) is often estimated by the Kaplan-Meier (KM) method censoring for competing endpoints, primarily death. This method overestimates the incidence of graft loss. METHODS: In 3157 adult KTX recipients followed for a mean of 79.2 months, …

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Standardized reporting of monoclonal immunoglobulin–associated renal diseases: recommendations from a Mayo Clinic/Renal Pathology Society Working Group

Sanjeev Sethi, Cynthia C. Nast, Vivette D. D’Agati, Fernando C. Fervenza et autres

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Inflammation in areas of fibrosis: The DeKAF prospective cohort

Arthur J. Matas, Erika S. Helgeson, Robert S. Gaston, Fernando G. Cosio et autres

Inflammation in areas of fibrosis (i-IFTA) in posttransplant biopsy specimens has been associated with decreased death-censored graft survival (DC-GS). Additionally, an i-IFTA score ≥ 2 is part of the diagnostic criteria for chronic active TCMR (CA TCMR). We examined the impact of …

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