Joshua D. Stein

Linking multicenter electronic health records with socioeconomic data to examine receipt of standard versus premium intraocular lenses

Alaa Mohamedali, Azraa S. Chaudhury, Adovich S. Rivera, Joshua D. Stein et autres

Purpose: Premium intraocular lenses (IOLs) can improve visual outcomes and reduce dependence on glasses but often require out-of-pocket payment. The socioeconomic factors influencing their selection remain poorly understood. Leveraging a multi-institutional electronic health record dataset, we examined demographic and socioeconomic factors associated …

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Rates and associated risk factors for cataract surgery complications in academic medical centers

Gabriella S. Danziger, Dustin D. French, Yang Li, Chris Andrews et autres

PURPOSE: To evaluate sociodemographic and clinical factors with postoperative complications after cataract surgery at academic medical centers in the United States. SETTING: 16 U.S. academic medical centers contributing to the Sight Outcomes Research Collaborative (SOURCE) big data repository. DESIGN: Retrospective, multicenter cohort …

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Leveraging Sight Outcomes Research Collaborative (SOURCE) Data to Predict Initial Presentation With Advanced Open-Angle Glaucoma

Rithambara Ramachandran, Aaron T. Zhao, Yinxi Yu, Joshua D. Stein

PURPOSE: To investigate factors associated with initial presentation at tertiary health systems with advanced primary open-angle glaucoma (OAG) in either eye. DESIGN: Cross-sectional study. SUBJECTS: Adults >40 years old diagnosed with OAG initially presenting at one of eleven SOURCE consortium sites between …

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Quality of Care in Patients With Newly Diagnosed Glaucoma

Maryam Ige, Dustin D. French, Azraa S. Chaudhury, Yang Li et autres

Importance: Various communities continue to experience relatively high rates of glaucoma-related visual impairment and blindness. Identifying potential nonmedical influences on glaucoma outcomes may lead to strategies to improve glaucoma care. Objective: To assess possible associations between nonmedical variables and quality of glaucoma …

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Ensemble learning to enhance accurate identification of patients with glaucoma using electronic health records

Tushar Mungle, Behzad Naderalvojoud, Chris Andrews, Hong Su An et autres

Abstract Objectives Existing ophthalmology studies for clinical phenotypes identification in real-world datasets (RWD) rely exclusively on structured data elements (SDE). We evaluated the performance, generalizability, and fairness of multimodal ensemble models that integrate real-world SDE and free-text data compared to SDE-only models …

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The Association of Social Determinants of Health on Monitoring for Disease Progression Among Patients With Primary Open-Angle Glaucoma

K. C. Kanwar, Rithambara Ramachandran, Joshua D. Stein, Chris Andrews et autres

Purpose: To examine the association of race, ethnicity, and other social determinants of health (SDH) on receipt of optic nerve (ON) evaluation in accordance with National Quality Forum (NQF) and the American Academy of Ophthalmology (AAO) guideline-based metrics. Methods: This was a …

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Validation of a Visual Field Prediction Tool for Glaucoma: A Multicenter Study Involving Patients With Glaucoma in the United Kingdom

Arlen Dean, Dun Jack Fu, Mohammad Zhalechian, Mark P. Van Oyen et autres

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P167: Variants in RPAP3 are associated with normal-pressure glaucoma*

William Presley, Sarah J. Garnai, Bin Guan, Sayoko E. Moroi et autres

or moderate; there was 1 serious AE (gastroenteritis unrelated to the study drug, which occurred during the post-treatment safety follow-up period).Linear PK was observed over the titrated dose range.A one-compartment linear population PK model was developed.Apparent clearance of 1.89 L/h, apparent volume …

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Race, Social Determinants of Health, and the Quality of Diabetic Eye Care

Azraa S. Chaudhury, Maryam Ige, Shikha Marwah, Xueqing Zhou et autres

Importance: Besides race, little is known about how other social determinants of health (SDOH) affect quality of diabetic eye care. Objective: To evaluate the association between multiple SDOH and monitoring for diabetic retinopathy (DR) in accordance with clinical practice guidelines (CPGs). Design, …

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Big data and electronic health records for glaucoma research

Isaac A. Bernstein, Karen S. Fernández, Joshua D. Stein, Suzann Pershing et autres

The digitization of health records through electronic health records (EHRs) has transformed the landscape of ophthalmic research, particularly in the study of glaucoma. EHRs offer a wealth of structured and unstructured data, allowing for comprehensive analyses of patient characteristics, treatment histories, and …

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When We Collide: Sex, Social Risk, and Jewish Ethics by Rebecca J. Epstein-Levi

Joshua D. Stein

Ocular Condition a Billing Records Reviewed, No. Encounters Coded

Kelly W. Muir, Chirag Gupta, Prakriti Gill, Joshua D. Stein