2026
article
OpenAlex
Gaspard Gerschenfeld, Bertrand Lapergue, Julien Labreuche, Jean François Albucher et autres
BACKGROUND: Endovascular thrombectomy (EVT) is now the standard treatment for patients with large cerebral infarcts. However, the benefit of intravenous thrombolysis before EVT (IVT+EVT) in this setting is uncertain. METHODS: We conducted a post hoc analysis of the Large Stroke Therapy Evaluation …
fr, us
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Gaultier Marnat, Bertrand Lapergue, Julien Labreuche, Vincent Costalat et autres
Background and Purpose: The optimal anesthetic regimen for the endovascular treatment (EVT) of stroke due to large vessel occlusion remains unclear. Patients with large infarct core on initial imaging constitute a specific subpopulation. The aim of this study was to investigate the …
fr, us
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Jéromine Fasille, Mialitiana Solo Nomenjanahary, Dorothée Faille, Capucine Habay et autres
BACKGROUND AND PURPOSE: Cryptogenic strokes, accounting for 25%-40% of ischemic strokes, represent a major challenge in secondary prevention due to their uncertain etiology and high recurrence risk. Identifying biomarkers to reliably distinguish cardioembolic (CE) strokes among embolic strokes of undetermined source (ESUS) …
fr
(code pays fourni par la source)
2026
conference-abstract
OpenAlex
Adrien ter Schiphorst, Cyril Dargazanli, Julien Labreuche, Francesca Rapido et autres
Background and Purpose: Futile recanalization, defined as the absence of functional independence despite successful recanalization, remains a significant limitation of endovascular treatment (EVT) for large vessel occlusion (LVO) stroke. Inflammation has emerged as a key contributor to brain reperfusion injury. We investigated …
fr, us
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Adrien ter Schiphorst, Caroline Arquizan, Guillaume Turc, Julien Labreuche et autres
BACKGROUND AND PURPOSE: Whether perfusion-diffusion mismatch modifies treatment effect of mechanical thrombectomy (MT) for large strokes is poorly known. To address this question, we conducted a post hoc secondary analysis of the Large Stroke Therapy Evaluation (LASTE) randomized controlled trial (RCT). METHODS: …
fr, us, es
(code pays fourni par la source)
2026
conference-abstract
OpenAlex
Adrien ter Schiphorst, Pierre Seners, Cyril Dargazanli, Julien Labreuche et autres
Background and Purpose: Persistent hypoperfusion despite successful endovascular treatment (EVT) for acute ischemic stroke (AIS) due to large-vessel occlusion (LVO), which results from either residual distal macrovascular occlusion or microvascular dysfunction ("no-reflow"), is increasingly recognized as a potential contributor to poor outcome. …
fr, us
(code pays fourni par la source)
2026
article
OpenAlex
Adrien ter Schiphorst, Pierre Seners, Cyril Dargazanli, Julien Labreuche et autres
BACKGROUND: Persistent hypoperfusion despite successful endovascular treatment (EVT) for acute ischemic stroke (AIS) due to large-vessel occlusion is increasingly recognized as associated with poor outcome. It may result from residual distal macrovascular occlusion or microvascular dysfunction (no-reflow). We aimed to characterize early …
fr, us, Maroc
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Jean-Christophe Lafontaine, Cécile Bordier, Julien Labreuche, Tifanie Alberto et autres
Abstract Optic nerve is now included as a fifth typical location in multiple sclerosis diagnosis criteria. The radiologically isolated syndrome represents the earliest stage of multiple sclerosis. Previous optical coherence tomography studies in this asymptomatic context reported no or slight retinal thickness …
fr
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Christian Petitjean, Julien Labreuche
BACKGROUND: Diabetes is an independent risk factor for ischemic stroke. This study was undertaken to determine whether hemodynamic cerebral ischemia (HCI), which increases stroke severity, is more frequent in diabetic patients. METHODS: Between 01/01/1990 and 30/06/2019, we revascularized 4117 carotid bifurcations in …
fr
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Lucas Guillo, Oumaya El Oumami, Guillaume Le Cosquer, Louise Méheut et autres
INTRODUCTION: Women with endometriosis have a higher risk of developing inflammatory bowel diseases (IBDs). This study aimed to better understanding the impact of endometriosis on the course of IBD. METHODS: We conducted a retrospective cohort study in 18 French and Belgian IBD …
fr, be
(code pays fourni par la source)
2025
review
OpenAlex
Adrien ter Schiphorst, Caroline Arquizan, Julien Labreuche, Guillaume Turc et autres
BACKGROUND: Whether perfusion 'mismatch' modifies the effect of endovascular thrombectomy (EVT) in patients with large core ischemic stroke remains uncertain. METHODS: We conducted a Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)-compliant systematic review and meta-analysis of randomized controlled trials (RCTs) …
fr, us
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Cécile Yelnik, Anne Bauters, Julien Labreuche, Maximilien Desvages et autres
BACKGROUND: Patients with antiphospholipid syndrome (APS) display a wide range of clinical manifestations with similar immunological profile with the presence of lupus anticoagulant in around 70% of them. Although antiphospholipid antibodies (aPL) profile influences the risk of thrombosis in APS, APS risk …
fr
(code pays fourni par la source)