Accès ouvert
2025
erratum
OpenAlex
Encarnacion Montecino‐Rodriguez, Oscar I Estrada, Kenneth Dorshkind
Transient PU.1low fetal progenitors generate activated and memory T and B cells that colonize and are maintained in secondary lymphoid tissues and make an early and long-term contribution to the adult immune system.
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Accès ouvert
2025
article
OpenAlex
Erin Baker, Encarnacion Montecino‐Rodriguez, Shili Xu, Sotirios Tetradis et autres
B cell development declines with age, but how structural changes in the marrow environment contribute to that process is incompletely understood. Multiplexed volumetric imaging revealed that B lineage cells were enriched near bone, and trabecular bone in particular, in young mice. However, …
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Accès ouvert
2024
article
OpenAlex
Encarnacion Montecino‐Rodriguez, Oscar I Estrada, Kenneth Dorshkind
Hematopoietic stem cells and multipotential progenitors emerge in multiple, overlapping waves of fetal development. Some of these populations seed the bone marrow and sustain adult B- and T-cell development long-term after birth. However, others are present transiently, but whether they are vestigial …
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