Vincent James Cogliano

Hydrochlorothiazide, voriconazole, and tacrolimus

A.M.M. Antunes, Elizabeth K. Cahoon, Guosheng Chen, Vincent James Cogliano et autres

Carcinogenicity of hydrochlorothiazide, voriconazole, and tacrolimus

Vincent James Cogliano, Emanuela Corsini, A. Fournier, Heather H. Nelson et autres

fr (code pays fourni par la source)

Application of the Key Characteristics of Carcinogens to Bisphenol A

Karin Ricker, Vanessa Cheng, Ching‐Yi Hsieh, Feng C. Tsai et autres

The ten key characteristics (KCs) of carcinogens are based on characteristics of known human carcinogens and encompass many types of endpoints. We propose that an objective review of the large amount of cancer mechanistic evidence for the chemical bisphenol A (BPA) can …

us (code pays fourni par la source)

Bisphenol A and Cancer: A critical review of the epidemiologic literature for hazard assessment

Neela Guha, Gwendolyn Osborne, M. Elizabeth Marder, Martha S. Sandy et autres

BACKGROUND AND AIM: Bisphenol A (BPA) is a high production volume chemical with extensive consumer and industrial applications. BPA is detected in the majority of the US general population, despite a short half-life ( 6 hours) and declining exposures. We comprehensively reviewed …

us (code pays fourni par la source)

Conducting evaluations of evidence that are transparent, timely and can lead to health-protective actions

Nicholas Chartres, Jennifer Sass, David Gee, Simona Bălan et autres

BACKGROUND: In February 2021, over one hundred scientists and policy experts participated in a web-based Workshop to discuss the ways that divergent evaluations of evidence and scientific uncertainties are used to delay timely protection of human health and the environment from exposures …

us, gb, sa, de, it, nl, es (code pays fourni par la source)

Concordance between sites of tumor development in humans and in experimental animals for 111 agents that are carcinogenic to humans

Daniel Krewski, Jerry M. Rice, Michael G. Bird, Brittany Milton et autres

Since the inception of the IARC Monographs Programme in the early 1970s, this Programme has developed 119 Monograph Volumes on more than 1000 agents for which there exists some evidence of cancer risk to humans. Of these, 120 agents were found to …

ca, us, fr (code pays fourni par la source)

Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification

Michele A. La Merrill, Laura N. Vandenberg, Martyn T. Smith, William H. Goodson et autres

Endocrine-disrupting chemicals (EDCs) are exogenous chemicals that interfere with hormone action, thereby increasing the risk of adverse health outcomes, including cancer, reproductive impairment, cognitive deficits and obesity. A complex literature of mechanistic studies provides evidence on the hazards of EDC exposure, yet …

us, fr, gb, nl, jp (code pays fourni par la source)

Key characteristics of 86 agents known to cause cancer in humans

Daniel Krewski, Michael G. Bird, Mustafa Al‐Zoughool, Nicholas Birkett et autres

Since the inception of the International Agency for Research on Cancer (IARC) in the early 1970s, the IARC Monographs Programme has evaluated more than 1000 agents with respect to carcinogenic hazard; of these, up to and including Volume 119 of the IARC …

ca, sa, us, fr, gb (code pays fourni par la source)

Analysis of key characteristics of human carcinogens

Daniel Krewski, Mustafa Al‐Zoughool, Michael G. Bird, Nicholas Birkett et autres

Applying systematic approaches to hazard and dose–response assessment in the U.S. EPA's Integrated Risk Information System (IRIS)

Vincent James Cogliano

us (code pays fourni par la source)

Key Characteristics of Carcinogens as a Basis for Organizing Data on Mechanisms of Carcinogenesis

Martyn T. Smith, Kathryn Z. Guyton, Catherine F. Gibbons, Jason M. Fritz et autres

BACKGROUND: A recent review by the International Agency for Research on Cancer (IARC) updated the assessments of the > 100 agents classified as Group 1, carcinogenic to humans (IARC Monographs Volume 100, parts A-F). This exercise was complicated by the absence of …

us, fr, au (code pays fourni par la source)

Lack of data drives uncertainty in PCB health risk assessments

Vincent James Cogliano

us (code pays fourni par la source)