Li Xiao

FLOW-GLIDE: Global–Local Interleaved Dynamics Estimator for Flow Field Prediction

Jing Su, Li Xiao, J.H. Wang

Accurate prediction of the flow field is crucial to evaluating the aerodynamic performance of an aircraft. While traditional computational fluid dynamics (CFD) methods solve the governing equations to capture both global flow structures and localized gradients, they are computationally intensive. Deep learning-based …

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Dual energy CT-based Radiomics for identification of myocardial focal scar and artificial beam-hardening

Linqi Zeng, Feng Hu, Peixin Qin, Taoyu Jia et autres

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PPP3CB inhibits pancreatic cancer progression by promoting ATOH8 translocation and transcriptionally regulating Sp1

Dong Xiao, Lixia Wu, Libao Gong, Daijia Huang et autres

AIMS: Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy which lacks effective therapeutic targets. We previously demonstrated that low PPP3CB expression correlates with poor prognosis in PDAC. This study aims to investigate the function and underlying mechanism of PPP3CB in pancreatic …

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Antibody response after SARS-CoV-2 infection or vaccination in China: A cross-sectional study

Peng Zhu, Qingyan Chen, Xia Xu, Deyong Tan et autres

It is crucial to understand how antibodies are generated after the individual has been infected or vaccinated to control the COVID-19 pandemic and develop future vaccination strategies. The level of SARS-CoV-2 IgG/IgM was assessed in 348 plasma samples in the current study. …

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Learning Airfoil Flow Field Representation via Geometric Attention Neural Field

Li Xiao, Mingjie Zhang, Xinghua Chang

Numerical simulation in fluid dynamics can be computationally expensive and difficult to achieve. To enhance efficiency, developing high-performance and accurate surrogate models is crucial, where deep learning shows potential. This paper introduces geometric attention (GeoAttention), a method that leverages attention mechanisms to …

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Preoperative chemotherapy plus immune checkpoint inhibitors as conversion therapy in pancreatic cancer patients with initially unresectable liver-limited metastases: a case report

Li Xiao, Haoqi Zhang, Chunlu Tan, Xubao Liu et autres

Pancreatic cancer (PC) is a lethal tumor, and overall survival (OS) is poor, especially for patients with liver metastases. Herein, we report a 55-year-old female who presented with right upper quadrant pain. Computed tomography (CT) of the upper abdomen revealed a large …

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PPP3CB inhibits pancreatic cancer progression via promoting translocation of ATOH8 and further transcriptionally regulating Sp1

Junjie Hang, Dong Xiao, Lixia Wu, Libao Gong et autres

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[Effects of Ziyin Liangxue Formula Combined with Prednisone on Immune Function and ST2/IL-33 Pathway in Mice with Immune Thrombocytopenia].

Bingjie Zhao, Hong Che, Lian Hu, Wen‐Jing Yi et autres

OBJECTIVE: formula combined with prednisone on immune function and the ST2/IL-33 pathway in mice with immune thrombocytopenia. METHODS: formula + prednisone group (0.2 ml/10 g), 8 mice in each group, and the other 8 mice were set as control group. The drugs …

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Sirt6 promotes DNA damage repair in osteoarthritis chondrocytes by activating the Keap1/Nrf2/HO-1 signaling pathway

Lingwei Mao, Qin-Yi Jiang, Nan Meng, Li Xiao et autres

The aim of this study was to explore the effect and mechanism of Sirt6 on DNA damage repair in OA chondrocytes. Cartilage tissues were collected from OA patients with knee arthroplasty and traumatic amputation patients without OA. Besides, 7-week-old male C57BL/6 mice …

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The future landscape of immunology in COPD: A bibliometric analysis

Yujie Sun, Fan Jiang, Rui Li, Li Xiao

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Dinaciclib exerts a tumor-suppressing effect via β-catenin/YAP axis in pancreatic ductal adenocarcinoma

Yichen Li, Zhenjiang Zheng, Li Xiao, Yonghua Chen et autres

Dinaciclib, a cyclin-dependent kinase-5 (CDK5) inhibitor, has significant anti-tumor properties. However, the precise mechanism of dinaciclib requires further investigation. Herein, we investigated the anti-tumor functions and molecular basis of dinaciclib in pancreatic ductal adenocarcinoma (PDAC). PDAC and matched para-carcinoma specimens were collected …

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The principle and application of relaxation time distribution

Wenyong Jiang, Kaicong Yang, Gongwei Wang, Juntao Lu et autres

Electrochemical impedance spectroscopy (EIS) is an electrochemical measurement method that uses a small amplitude sine wave potential or current as a disturbance signal. With the development of impedance measurement instrument technology, the test and application of EIS are becoming more and more …