Darío Rocha

Dual PD-L1/TIGIT blockade induces PNAd⁺ HEV-like vessels and CD62L⁺ lymphocyte recruitment, driving rhabdoid tumor rejection

Stéphanie Fitte-Duval, S Silva, Rafael Mena‐Osuna, Owen Hoare et autres

Abstract Rhabdoid tumors (RTs) are aggressive pediatric malignancies with poor prognosis and limited immunotherapy options. Here, we investigate the therapeutic potential of combined PD-L1 (Programmed cell death ligand 1) and TIGIT (T cell immunoreceptor with Ig and ITIM domains) immune checkpoint blockade …

fr (code pays fourni par la source)

Table 3 from Genetic Ancestry, Intrinsic Tumor Subtypes, and Breast Cancer Survival in Latin American Women

Daniela Alves da Quinta, Darío Rocha, Cristian Yáñez, Renata Binato et autres

Univariate and multivariate Cox proportional hazard models for overall survival for every 10% increase of EUR or IA ancestry

Supplementary Information from Genetic Ancestry, Intrinsic Tumor Subtypes, and Breast Cancer Survival in Latin American Women

Daniela Alves da Quinta, Darío Rocha, Cristian Yáñez, Renata Binato et autres

Supplementary information and List of LACRN Investigators

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Supplementary Figure S2 from Genetic Ancestry, Intrinsic Tumor Subtypes, and Breast Cancer Survival in Latin American Women

Daniela Alves da Quinta, Darío Rocha, Cristian Yáñez, Renata Binato et autres

Distribution of immunohistochemistry (IHC) breast cancer subtypes according to the four most prevalent ancestral components in Latin America.

Figure 2 from Genetic Ancestry, Intrinsic Tumor Subtypes, and Breast Cancer Survival in Latin American Women

Daniela Alves da Quinta, Darío Rocha, Cristian Yáñez, Renata Binato et autres

Distribution of PAM50 breast cancer subtypes according to the four most prevalent ancestral components in Latin America: European (EUR), Indigenous American (IA), African (AFR), and East Asian (EAS). Bars shown correspond to post hoc Dunn test pairwise comparisons <0.05. HER2E, HER2-enriched; LumA, …

Figure 1 from Genetic Ancestry, Intrinsic Tumor Subtypes, and Breast Cancer Survival in Latin American Women

Daniela Alves da Quinta, Darío Rocha, Cristian Yáñez, Renata Binato et autres

Population structure of the 951 patients with breast cancer of the LACRN-MPBCS cohort included in this study. A, ADMIXTURE ancestry estimations obtained assuming four ancestral components for each country of origin (B) Principal component analysis (PCA) of data from all LACRN-MPBCS patients …

Data from Genetic Ancestry, Intrinsic Tumor Subtypes, and Breast Cancer Survival in Latin American Women

Daniela Alves da Quinta, Darío Rocha, Cristian Yáñez, Renata Binato et autres

Abstract This study investigates the relationship between genetic ancestry, breast cancer subtypes, and survival outcomes among 951 locally advanced breast cancer cases from Argentina, Brazil, Chile, Mexico, and Uruguay, participating in the Molecular Profile of Breast Cancer Study. Array-based genotyping and ADMIXTURE …

Supplementary Figure S1 from Genetic Ancestry, Intrinsic Tumor Subtypes, and Breast Cancer Survival in Latin American Women

Daniela Alves da Quinta, Darío Rocha, Cristian Yáñez, Renata Binato et autres

Distribution of the four ancestries (rows) according to the MPBCS participating institutions in each LACRN country (columns).

Table 2 from Genetic Ancestry, Intrinsic Tumor Subtypes, and Breast Cancer Survival in Latin American Women

Daniela Alves da Quinta, Darío Rocha, Cristian Yáñez, Renata Binato et autres

Association between HER2 status, IHC and PAM50 subtypes, and EUR genetic ancestry (for every 10% increase in EUR or IA ancestry component)

Table 1 from Genetic Ancestry, Intrinsic Tumor Subtypes, and Breast Cancer Survival in Latin American Women

Daniela Alves da Quinta, Darío Rocha, Cristian Yáñez, Renata Binato et autres

By-country epidemiologic and clinical characteristics of the 951 patients of the LACRN-MPBCS included in this study

Genetic Ancestry, Intrinsic Tumor Subtypes, and Breast Cancer Survival in Latin American Women

Daniela Belén Alves Da Quinta, Darío Rocha, Cristian Yáñez, Renata Binato et autres

This study investigates the relationship between genetic ancestry, breastcancer subtypes, and survival outcomes among 951 locally advanced breastcancer cases from Argentina, Brazil, Chile, Mexico, and Uruguay, participatingin the Molecular Profile of Breast Cancer Study. Array-basedgenotyping and ADMIXTURE analysis were used for genetic …

Genetic Ancestry, Intrinsic Tumor Subtypes, and Breast Cancer Survival in Latin American Women

Daniela Alves da Quinta, Darío Rocha, Cristian Yáñez, Renata Binato et autres

This study investigates the relationship between genetic ancestry, breast cancer subtypes, and survival outcomes among 951 locally advanced breast cancer cases from Argentina, Brazil, Chile, Mexico, and Uruguay, participating in the Molecular Profile of Breast Cancer Study. Array-based genotyping and ADMIXTURE analysis …

ar, cl, br, us, uy, mx (code pays fourni par la source)