Yu Gou

Injectable ROS-scavenging and NIR-responsive nanocomposite hydrogel for staphylococcus aureus-infected diabetic wound healing

Ming Cai, Zhao Liu, Xun Sun, Ziming Liao et autres

Chronic diabetic wounds are often complicated by persistent infections and oxidative stress, which impede effective healing. In this study, we developed an injectable, dual-responsive nanocomposite hydrogel designed to simultaneously scavenge reactive oxygen species (ROS) and deliver photothermal and photodynamic therapy for wound …

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Epidemiology of Chlamydia pneumoniae infection in children with acute respiratory tract infections, Chengdu, 2022–2023

Yifei Duan, Yu Wu, Yu Gou, Xiaoqin Liu et autres

Background Chlamydia pneumoniae is a common pathogen involved in acute respiratory tract infections (ARTIs) in children. Methods Children with ARTIs attending the West China Second Hospital of Sichuan University from January 2022 to December 2023 were selected. IgM antibodies against Chlamydia pneumoniae …

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Enteral insulin for full enteral feeding in preterm infants: A systematic review and meta-analysis

Haodongfang Zhang, Lixue Ouyang, Yu Gou

BACKGROUND: Recent studies have demonstrated that recombinant human insulin (rh-insulin) can shorten the time of full enteral feeding (FEF) and is relatively safe in preterm infants. However, there is no consensus on the safety and effectiveness of enteral insulin. The aim of …

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Work Stress and Its Association with Cardiovascular Events in Occupational Populations: A Systematic Review and Meta-analysis

Hui Dong, Lei Yang, Yu Gou, Ying Zhang et autres

Abstract Introduction: Cardiovascular disease (CVD) is the top global killer, with work stress as a risk factor. The choice of assessment tools for work stress significantly affects our understanding of its role in CVD outcomes. This systematic review and meta-analysis focused on …

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Sema3A relieves neuropathic pain by reducing eIF2α phosphorylation via suppressing PI3K/Akt/mTOR pathway

Tingting Hu, Miaoyi Pang, Qingyu Sun, Yu Gou et autres

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Efficient electrochemical detection of pancreatic cancer marker CA19-9 using biosynthesized gold nanoparticles from mint extract for electrode modification

Yu Liu, Bude Su, Jianxin Shen, Yu Gou et autres

This study presents a novel electrochemical biosensor for the detection of CA19–9, a crucial pancreatic cancer biomarker, utilizing gold nanoparticles (AuNPs) biosynthesized from mint extract. The green synthesis approach yielded well-dispersed, spherical AuNPs with a characteristic surface plasmon resonance peak at 520 …

A retrospective study of arthroscopic treatment for patients with bordline developmental dysplasia of the hip

Yu Gou, Zi Zhang, Binyang Meng, Jiangang Cao et autres

PURPOSE: Hip arthroscopy is effective in treating bordline developmental dysplasia of the hip (BDDH), but there are only a few clinical reports in China, and its postoperative failure rate is still a problem that cannot be ignored. The aim of this study …

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Establishment of cutoff values for anti-β2 glycoprotein I antibodies in women of reproductive age in Southwest China

Chenxi Liu, Lingyi Yan, Menglan Zhang, Yu Gou et autres

Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by vascular thrombosis and obstetric morbidity, with accurate laboratory examination of antiphospholipid antibodies (aPLs) being crucial for diagnosis. This study focused on anti-β2 glycoprotein I (aβ2GPI) antibodies and aimed to establish the first population-based …

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Neurosyphilis Presenting as Psychiatric Symptoms at Younger Age: A Case Report

Hongyan Li, Haoyu Wang, Yifei Duan, Yu Gou et autres

Abstract: Neurosyphilis is a central nervous system infection caused by Treponema pallidum that imitates various neurological and mental disorders. Therefore, patients with this disease are prone to misdiagnoses. Here, we report a case of neurosyphilis with a psychotic disorder as the main …

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Parathyroid hormone (1–34) retards the lumbar facet joint degeneration and activates Wnt/β-catenin signaling pathway in ovariectomized rats

Yu Gou, Hetong Li, Xun Sun, Desheng Chen et autres

PURPOSE: Facet joint degeneration (FJD) is a major cause of low back pain. Parathyroid hormone (PTH) (1-34) is commonly used to treat osteoporosis. However, little is known about its effects on FJD induced by estrogen deficiency. This study aims to investigate the …

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The impacts on bone structures and metabolisms by high-fat diet caused osteoporosis in mice: a meta-analysis and systematic review

Qiangqiang Lian, Hetong Li, Faming Tian, Yu Gou et autres

Osteoporosis (OP) is one of the epidemic diseases worldwide. Recently, a high-fat diet (HFD) makes the effects on skeletal microarchitecture still unclear. To explain the problem, we searched studies from PubMed, Embase, Web of Science, and Cochrane library to investigate the effect …

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Exploring the anti-osteoporotic potential of simvastatin and metformin: a comprehensive Mendelian randomization and animal experiment investigation

Hui Zhou, Jin Zhang, Peipei He, Yu Gou et autres