Marie Simon

Intercellular transfer of mammary extracellular vesicles : tri-dimensional spatial analysis and dysregulation by titanium dioxide nanoparticle exposure

Marie Simon

Transfert intercellulaire des vésicules extracellulaires mammaires : analyse spatiale tridimensionnelle et perturbation induite par l'exposition à des nanoparticules de dioxyde de titane Les vésicules extracellulaires (VEs) sont des particules de taille nano- à micrométrique délimitées par une bicouche lipidique, sécrétées par tous …

fr (code pays fourni par la source)

Transfert intercellulaire des vésicules extracellulaires mammaires : analyse spatiale tridimensionnelle et perturbation induite par l'exposition à des nanoparticules de dioxyde de titane

Marie Simon

Extracellular vesicles (EVs) are nano- to micrometer-sized lipid bilayer-delimited vesicles secreted by all cell types and involved in intercellular communication. EVs originate either from the plasma membrane, typically enriched in the tetraspanin CD9, or from intracellular multivesicular bodies (MVBs), typically enriched in …

La bouche en fin de vie

Marie Simon

En Occident, la bouche du patient en fin de vie est criante de représentations. Elle est à la fois lieu de tendresse, de paroles, d’échanges physiques et de plaisir sensoriel. À l’approche de la fin de vie, la perte d’autonomie s’accentue et, …

fr (code pays fourni par la source)

Les représentations des soignants face à la bouche du patient en fin de vie

Marie Simon

fr (code pays fourni par la source)

Cost-Utility Analysis of Accelerated and Standard Strategies for Renal Replacement Therapy Initiation

Jeff Round, İlke Akpinar, Charles Yan, Natasha Patel et autres

Importance: Little is known about the long-term costs and outcomes related to strategies for timing of initiation of kidney replacement therapy (KRT) in critically ill patients with severe acute kidney injury (AKI). Objective: To estimate the cost-utility and cost-effectiveness of accelerated KRT …

ca, il, us (code pays fourni par la source)

Peripheral neuropathy during long-term suppressive therapy with tedizolid: a case series

Tomaso Beringheli, Clément Javaux, Sandrine Roux, Evelyne Braun et autres

BACKGROUND AND OBJECTIVES: Due to its potentially better long-term haematologic tolerance compared to linezolid, tedizolid represents an attractive option for prolonged antibiotic therapy in complicated/chronic Gram-positive infections. However, there is little information regarding the risk of peripheral neurological toxicity, representing another obstacle …

it, fr, us, Maroc (code pays fourni par la source)

Ostéites de la base du crâne

Claire Triffault-Fillit, Fabien Craighero, Céline Dupieux, Clémentine Daveau et autres

fr (code pays fourni par la source)

Kala-azar in solid organ transplant recipients, a case report and literature review. Ancient disease, old world, new patients

Amélie Bouvier, Méja Rabodonirina, Damien Dupont, Valérie Hervieu et autres

fr, Maroc (code pays fourni par la source)

PD-L1+ plasma cells suppress T lymphocyte responses in patients with sepsis and mouse sepsis models

Morgane Gossez, Clara Vigneron, Alexandra Vandermoeten, Margot Lepage et autres

Abstract Sepsis, a leading cause of death in intensive care units, is associated with immune alterations that increase the patients’ risk of secondary infections and mortality, so better understandings of the pathophysiology of sepsis-induced immunosuppression is essential for the development of therapeutic …

fr (code pays fourni par la source)

Renal replacement therapy in an intensive care unit: guidelines from the SRLF-GFRUP consensus conference

M. Jourdain, Ines Gragueb Chatti, Brahim Housni, Pierre Jaquet et autres

BACKGROUND: Although largely used, the place of extracorporeal renal replacement therapy (RRT) in acute kidney injury (AKI) in intensive care unit (ICU) patients has yet to be clarified. The French Intensive Care Society (Société de Réanimation de Langue Française, SRLF) and the …

fr, Maroc, Sénégal (code pays fourni par la source)

Treatment of positive catheter tip culture without bloodstream infections in critically ill patients. A case-cohort study from the OUTCOMEREA network

Niccolò Buetti, Jean‐Ralph Zahar, Mireille Adda, Stéphane Ruckly et autres

PURPOSE: This study aimed to evaluate the impact on subsequent infections and mortality of an adequate antimicrobial therapy within 48 h after catheter removal in intensive care unit (ICU) patients with positive catheter tip culture. METHODS: We performed a retrospective analysis of …

ch, fr, us (code pays fourni par la source)

Antibiotic definitive treatment in ventilator associated pneumonia caused by AmpC-producing Enterobacterales in critically ill patients: a prospective multicenter observational study

Matthieu Petit, Frank Bidar, Quentin Fossé, Lucie Lefèvre et autres

BACKGROUND: Ventilator associated pneumonia (VAP) due to wild-type AmpC-producing Enterobacterales (wtAE) is frequent in intensive care unit (ICU) patients. Despite a low level of evidence, definitive antimicrobial therapy (AMT) with third generation cephalosporins (3GCs) or piperacillin is discouraged. METHODS: Observational prospective study …

fr (code pays fourni par la source)