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Profil bibliographique

Jan Malý

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

32Publications signalées
613Citations signalées
3Affiliations récentes

Les institutions déclarées

Les domaines associés

Renin-Angiotensin System StudiesCardiac electrophysiology and arrhythmiasReceptor Mechanisms and SignalingIon channel regulation and functionHormonal Regulation and Hypertension

Les publications récentes

Accès ouvert 2024 article OpenAlex

Chemical pleurodesis with povidone-iodine (Betadine) in congenital chylothorax: personal experience and review of literature

J Náhlovský, Radek Štichhauer, Jana Lešková, Jan Malý et autres

Vrozený chylothorax je závažné a obtížně léčitelné onemocnění s vysokou mortalitou. Použitím chemické pleurodézy lze omezit nutnost chirurgické léčby, avšak dosud není kvůli nedostatku důkazů jednoznačná shoda nad optimální chemickou látkou. Ve dvou kazuistikách popisujeme vlastní zkušenost s chemickou pleurodézou jodovaným povidonem …

cz, sk (code pays fourni par la source)

1 citation Česko-slovenská pediatrie
Accès ouvert 2023 article OpenAlex

Familial hypercholesterolaemia in children and adolescents from 48 countries: a cross-sectional study

Kanika Dharmayat, Antonio J. Vallejo‐Vaz, Christophe Stevens, Julia Brandts et autres

BACKGROUND: Approximately 450 000 children are born with familial hypercholesterolaemia worldwide every year, yet only 2·1% of adults with familial hypercholesterolaemia were diagnosed before age 18 years via current diagnostic approaches, which are derived from observations in adults. We aimed to characterise …

in, gb (code pays fourni par la source)

88 citations The Lancet
Accès ouvert 2022 article OpenAlex

Structural modeling of the hERG potassium channel and associated drug interactions

Jan Malý, Aiyana M. Emigh, Kevin R. DeMarco, Kazuharu Furutani et autres

-Related Gene (hERG), is expressed in cardiac myocytes, where it is crucial for the membrane repolarization of the action potential. Gating of the hERG channel is characterized by rapid, voltage-dependent, C-type inactivation, which blocks ion conduction and is suggested to involve constriction …

us, jp (code pays fourni par la source)

25 citations Frontiers in Pharmacology
Accès ouvert 2021 preprint OpenAlex

Structural modeling of the hERG potassium channel and associated drug interactions

Jan Malý, Aiyana M. Emigh, Kevin R. DeMarco, Kazuharu Furutani et autres

Abstract The voltage-gated potassium channel, KV11.1, encoded by the human Ether-à-go-go - Related Gene (hERG) is expressed in cardiac myocytes, where it is crucial for the membrane repolarization of the action potential. Gating of hERG channel is characterized by rapid, voltage-dependent, C-type …

us, jp (code pays fourni par la source)

1 citation bioRxiv (Cold Spring Harbor Laboratory)
2020 article OpenAlex

Gravidita u pacientek po augmentaci měchýře střevním segmentem - naše zkušenosti

Ivo Novák, Marián Kacerovský, Sylvie Dusilová‐Sulková, Jan Malý

Novak I, Kacerovský M, Dusilova‑Sulkova S, Malý J. Gravidita u pacientek po augmentaci měchýře střevnim segmentem - nase zkusenosti. U žen po rekonstrukcich dolnich mocových cest (DMC) augmentaci pro zavažne vrozene urogenitalni anomalie neni gravidita kontraindikovana. Přirozena cesta otěhotněni je možna. Přestože …

0 citations Česká urologie
Accès ouvert 2014 article OpenAlex

The relationship between estimated GFR based on the CKD-EPI formula and renal inulin clearance in potential kidney donors

O Schück, Vladimı́r Teplan, Jan Malý, Janka Franeková et autres

It is not yet clear whether or not renal function in the living donor can be sufficiently assessed by estimated glomerular filtration rate (GFR) using creatinine-based equations. The present paper investigates the relationship between GFR values determined using renal inulin clearance (Cin) …

us, fr, cz (code pays fourni par la source)

6 citations Clinical Nephrology

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