Aller au contenu principal
Profil bibliographique

Hoyin Lam

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

30Publications signalées
1458Citations signalées
3Affiliations récentes

Les institutions déclarées

Les domaines associés

HIV/AIDS drug development and treatmentHIV Research and TreatmentProtease and Inhibitor MechanismsCell Adhesion Molecules ResearchViral gastroenteritis research and epidemiology

Les publications récentes

Accès ouvert 2023 article OpenAlex

CD73 controls Myosin II–driven invasion, metastasis, and immunosuppression in amoeboid pancreatic cancer cells

Rémi Samain, Óscar Maiques, Joanne Monger, Hoyin Lam et autres

Pancreatic ductal adenocarcinoma (PDAC) has a very poor prognosis because of its high propensity to metastasize and its immunosuppressive microenvironment. Using a panel of pancreatic cancer cell lines, three-dimensional (3D) invasion systems, microarray gene signatures, microfluidic devices, mouse models, and intravital imaging, …

gb, sg, pl, fi, es (code pays fourni par la source)

35 citations Science Advances
Accès ouvert 2019 article OpenAlex

TIMP-2 secreted by monocyte-like cells is a potent suppressor of invadopodia formation in pancreatic cancer cells

Christian Benzing, Hoyin Lam, Chi Man Tsang, Alexander Rimmer et autres

BACKGROUND: Monocytes are a major component of the tumor microenvironment (TME) in pancreatic ductal adenocarcinoma (PDAC). However, the complex interactions between tumor cells and monocytes and their role in tumor invasion have not been fully established. METHODS: To specifically test the impact …

gb, de, hk (code pays fourni par la source)

30 citations BMC Cancer
Accès ouvert 2019 preprint OpenAlex

TIMP-2 secreted by monocytes-like cells is a potent suppressor of invadopodia formation in pancreatic cancer cells

Christian Benzing, Hoyin Lam, Chi Man Tsang, Alexander Rimmer et autres

Abstract Background Monocytes are a major component of the tumor microenvironment (TME) in pancreatic ductal adenocarcinoma (PDAC). However, the complex interactions between tumor cells and monocytes and their role in tumor invasion have not been fully established. Methods To specifically test the …

hk, gb, de (code pays fourni par la source)

0 citations Research Square
Accès ouvert 2019 preprint OpenAlex

TIMP-2 secreted by monocytes is a potent suppressor of invadopodia formation in pancreatic cancer cells

Christian Benzing, Hoyin Lam, Chi Man Tsang, Yoana Arroyo-Berdugo et autres

Abstract Background Monocytes are a major component of the tumor microenvironment (TME) in pancreatic ductal adenocarcinoma (PDAC). However, the complex interactions between tumor cells and monocytes and their role in tumor invasion have not been fully established. Methods In this in vitro …

hk, gb, de (code pays fourni par la source)

0 citations Research Square
Accès ouvert 2019 article OpenAlex

Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment

Mirella Georgouli, Cecilia Herráiz, Eva Crosas‐Molist, Bruce Fanshawe et autres

ROCK-Myosin II drives fast rounded-amoeboid migration in cancer cells during metastatic dissemination. Analysis of human melanoma biopsies revealed that amoeboid melanoma cells with high Myosin II activity are predominant in the invasive fronts of primary tumors in proximity to CD206 + CD163 …

gb, de, es (code pays fourni par la source)

178 citations Cell
Accès ouvert 2018 article OpenAlex

Comparative evaluation of a laboratory-developed real-time PCR assay and RealStar® Adenovirus PCR Kit for quantitative detection of human adenovirus

Samson S. Y. Wong, Cyril Chik‐Yan Yip, Siddharth Sridhar, Kit‐Hang Leung et autres

Human adenoviruses are common causes of community-acquired respiratory tract and enteric infections. Severe disseminated infections with high mortality rates may be seen in immunocompromised individuals. An accurate and cost-effective quantitative assay is essential not only for laboratory diagnosis of adenoviral infections, but …

hk, cn (code pays fourni par la source)

18 citations Virology Journal
2018 conference-abstract OpenAlex

3D spheroid invasion drug screen platform for pancreatic ductal adenocarcinoma.

Claire M. Wells, Hoyin Lam, Victoria Sanz‐Moreno, Verity Sabin et autres

e24212 Background: Pancreatic ductal adenocarcinoma (PDAC) is characterized by early cancer cell dissemination and poor response to current available treatments, highlighting the need for novel therapeutics. Desmoplastic stroma in the tumor microenvironment of PDAC contributes towards tumor growth, metastasis and resistance to …

gb (code pays fourni par la source)

0 citations Journal of Clinical Oncology

BNTIC News n’est pas le producteur de ces données. Les publications sont interrogées à la demande dans Crossref, OpenAIRE, DOAJ, Europe PMC, HAL, DataCite, AfricArXiv, ROR et la Banque mondiale, sans clé d’accès. OpenAlex reste optionnel. Aucun service payant n’est nécessaire et aucune donnée externe n’est enregistrée en base. Consulter les sources et leurs limites.