Machine learning-driven dissection of the obesity-ccRCC interface: FCGR2A emerges as a central coordinator of tumor-immune crosstalk
Zhongyuan He, Zheng Wang, X. Yin, Dawang Zheng et autres
Introduction: Obesity is a well-established risk modifier for clear cell renal cell carcinoma (ccRCC), yet the molecular mechanisms linking these conditions remain incompletely characterized. Methods: We developed a dual-disease analytical framework integrating transcriptomic harmonization (5 ccRCC cohorts, n=876; obesity adipose profiles) with …
cn (code pays fourni par la source)
0 citations
Frontiers in Oncology