Takeshi Ito

Large Language Models Can be Good Medical Annotators: A Case Study of Drug Change Detection in Japanese EHRs

Takeshi Ito, Tomohide Yoshie, Sohei Yoshimura, Nobuyuki Ohara et autres

In this study, we combined automatically generated labels from large language models (LLMs) with a small number of manual annotations to classify adverse event-related treatment discontinuations in Japanese EHRs. By fine-tuning JMedRoBERTa and T5 on 6,156 LLM-labeled records and 200 manually labeled …

jp (code pays fourni par la source)

Measurements of Interaction Cross Sections for 19–27F Isotopes

Akira Homma, M. Takechi, Takashi Ohtsubo, D. Nishimura et autres

jp, de, cn (code pays fourni par la source)

Measurement of γ-rays from Giant Resonances of 16O and 12C with Application to Supernova Neutrino Detection

I. Ou, Y. Yamada, T. Shirahige, Daisuke Fukuda et autres

jp (code pays fourni par la source)

Feasibility study to search for the rare $\gamma $-decay mode in $^{12}$C

M. Tsumura, T. Kawabata, Satoshi Adachi, Tatsuo Baba et autres

Stable Reproduction of Highlight Density for Dye Sublimation Printers

Haruo Yamashita, Takeshi Ito, Toshiharu Kurosawa

The dye sublimation transfer process, which allows continuous density gradation, is a process by which an image quality close to that of silver halide photographs can be obtained. However, deviations in process characteristics lead to deterioration in gradation characteristics in the highlight …

jp, us (code pays fourni par la source)

Human Pituitary Tumor Transforming Gene (hPTTG) Inhibits Human Lung Cancer A549 Cell Growth through Activation of p21WAF1/CIP1

Yi-Ming Mu, Koichi Oba, Toshihiko Yanase, Takeshi Ito et autres

Pituitary tumor transforming gene (PTTG) is a proto-oncogene cloned from rat GH4 cells. This gene was able to induce cell transformation in vitro and is also associated with p53-dependent and -independent apoptosis. In this study, we cloned human PTTG (hPTTG) from a …

jp, cn (code pays fourni par la source)

Sequential fluctuation pattern of serum des-γ-carboxy prothrombin levels detected by high-sensitive electrochemiluminescence system as an early predictive marker for hepatocellular carcinoma in patients with cirrhosis

Atsuya Shimizu, Katsuya Shiraki, Takeshi Ito, Kazushi Sugimoto et autres

Serum concentration levels of des-gamma-carboxy prothrombin (DCP), alpha-fetoprotein (AFP) and Lens culinaris agglutinin-reactive fraction (AFP-L3) are useful tumor markers for the diagnosis of hepatocellular carcinoma (HCC). Recently, a novel immunoassay using the electrochemiluminescence (ECLIA) was developed to enable measurement of low-concentration of …

jp (code pays fourni par la source)

Elevation of mRNA levels of tissue-type plasminogen activator and urokinase-type plasminogen activator in hippocampus and cerebral cortex following middle cerebral artery occlusion in rats

Takeshi Ito, Katsunobu Takenaka, Hideki Sakai, Shinichi Yoshimura et autres

Tissue-type plasminogen activator (tPA) and urokinase-type plasminogen activator (uPA) have been used for thrombolitic therapy. In contrast, it is suggested that these compounds might be involved in neuronal cell damage. The activation and the function of tPA and uPA are less understood …

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[Phe21]big endothelin‐1(18–34) and [Ala31]big endothelin‐1(18–34) inhibit the human endothelin‐converting enzyme‐1 (ECE‐1) expressed in CHO‐K1 cells in a different fashion

Wei Liu, Ryoichi Takayanagi, Takeshi Ito, Koichi Oba et autres

Endothelin-converting enzyme-1 (ECE-1) is one of the most important enzymes to convert big endothelin-1 (big ET-1) to ET-1. To identify the inhibitors of ECE-1, we examined the effects of variously substituted analogues of big ET-1 on ECE-1 activity using solubilized membranes prepared …

jp (code pays fourni par la source)

Quantitative determination of aldose reductase in human erythrocyte.

Chihiro Nishimura, Tomohiro Saito, Takeshi Ito, Masako Furue et autres