Marc R. Matthews

1014. Case Study. Skin Cell Suspension (SCSA) for Complex Necrotizing Soft Tissue Infections: A Case Series

Beverly Trutter, Marc R. Matthews, Lourdes Avila Castañón

Abstract Patient Presentation (age range, injury details, relevant history) Four females and 1 male with a median age of 62 with significant comorbidities who underwent reconstruction following extensive debridements. Clinical Challenges Large surgical wounds following multiple debridements. Intensive Care Unit Admission. One …

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Burn Injuries and Negative Pressure Wound Therapy

Marc R. Matthews

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Cellular, acellular, and matrix-like products (CAMPs) for soft-tissue reconstruction in acute surgical and traumatic wounds

Daniel L. Kapp, Thomas E Serena, Abigail E. Chaffin, Michael N Desvigne et autres

Human cells, tissues or cellular or tissuebased productsAuditable registration of compliance with CFR 1271 regulations and CFR 1271.10(a)criteria to ensure safety for human use without requiring pre-market approval or 510(k) clearance.

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V.A.C. RX-4 Deployment for Soft Tissue Coverage for the Trauma Patient: A Case Report

Emily R. Kindall, Courtney M. Janowski, Beverly Trutter, Sean F. O’Keefe et autres

Fasciotomies are commonly performed in the treatment of compartment syndrome to upper and lower extremities. Such operations improve distal soft tissue perfusion to the surrounding muscles and nerves negating amputations. Negative pressure wound therapy (NPWT) application to the open fasciotomy sites utilizes …

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Is the Laparoscope Only Meant for the Abdomen? —A Case Report Utilizing Laparoscopy to Evaluate a Thigh Abscess Cavity

Emily R. Kindall, Courtney M. Janowski, David L. Young, Luis G. Fernández et autres

Minimally invasive surgery and the use of endoscopy have been evolving for over 225 years. Traditionally used for general surgery procedures in the abdomen, the role of the laparoscope is now commonly used in not only the abdomen but also the retroperitoneum, …

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Definitive Closure Using an Ovine Reinforced Tissue Matrix in Contaminated Penetrating Abdominal Trauma

Luis G. Fernández, Jason Murry, Marc R. Matthews, Christopher L. Thompson et autres

BACKGROUND Cases involving penetrating abdominal trauma may be complex and often involve damage to multiple organ systems. Synthetic, biologic, and reinforced biologic matrices/reinforced tissue matrices (RBMs/RTMs) are frequently used in hernia repair and other surgical procedures requiring reinforcement, including trauma cases that …

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Clinical Observations in Patients With Open Abdomens Managed With Negative Pressure Therapy Using a Perforated Foam Dressing: A Limited Case Series With Brief Literature Review

Luis G. Fernández, Marc R. Matthews

INTRODUCTION: Emergency laparotomy has become an increasingly more frequent and expensive general surgery procedure in terms of cost and resource utilization. Primary fascial closure at the index procedure may not be feasible in many patients, requiring use of the open abdomen (OA)technique. …

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Synergistic Clinical Application of Synthetic Electrospun Fiber Wound Matrix in the Management of a Complex Traumatic Wound: Degloving Left Groin and Thigh Auger Injury

Luis G. Fernández, Carolina Orsi, Brandon Okeoke, Paige Moudy et autres

BACKGROUND: Managing complex traumatic soft tissue wounds involving a large surface area while attempting to optimize healing, avoid infection, and promote favorable cosmetic outcomes is challenging. Regenerative materials such as ECMs are typically used in wound care to enhance the wound healing …

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Multidisciplinary Expert Consensus Statements and Recommendations for Use of Hypochlorous Acid as a Solution for Negative Pressure Wound Therapy With Instillation

Paul Jeong Kim, Luis G. Fernández, Mary Ann Obst, Abigail E. Chaffin et autres

BACKGROUND: HOCl (eg, pHAp) preserved solutions have antimicrobial properties and are considered safe and effective for wound management. NPWTi-d (or NPWTi) is an established adjunctive wound modality for a variety of wound etiologies in various anatomic locations in which an instillate solution …

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The Efficient Application of Instilling Negative Pressure Wound Therapy With a Hypochlorous Acid-Preserved Wound Cleanser: A Case Series and Practical Advice

Marc R. Matthews, Luis G. Fernández, Michel Hermans, Debashish Chakravarthy

BACKGROUND: The use of negative pressure wound therapy with instillation and dwell time (NPWTi-d) has been shown to be effective in removing nonviable tissue, reducing bioburden, and promoting granulation tissue formation in acute and chronic infected wounds. OBJECTIVE: To illustrate the clinical …

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The Sandwich Technique for Quick and Efficient Application of Negative Pressure Wound Therapy to the Feet and Hands: A Case Report

Austin Rollins, Kristie Ho, Luis G. Fernández, Marisse A Lardizabal et autres

INTRODUCTION: NPWT is a surgical dressing that combines polyurethane foam with the subsequent application of continuous or intermittent negative pressure. NPWT facilitates granulation tissue production by macrostrain, microstrain and, if desired, fluid instillation. Sealing the polyurethane foam over the wound bed is …

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Early Experience and Recommendations for the Use of an Automated Estimator of Solution Volume for Negative Pressure Wound Therapy With Instillation

Paul Jeong Kim, Luis G. Fernández, Marc R. Matthews

INTRODUCTION: NPWTi is a device that combines the benefits of traditional NPWT with periodic irrigation. This automated device allows for preprogrammed cycles of dwelling of a solution and negative pressure onto the wound surface. Its adoption has been hampered by the perceived …

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