Rui Kun Pan

Glycogen Synthase Kinase 3 Is Essential for Intestinal Cell Niche and Digestive Function

Minggang Yang, Xiaohui Li, Rui Kun Pan, Ziye Yang et autres

WNT/β-catenin signaling is essential for intestinal stem cell development and self-renewal, while its dysregulation can drive tumorigenesis. GSK3, a key negative regulator of β-catenin, in intestinal homeostasis remains incompletely understood. In this study, we investigated the role of GSK3 in intestinal development, …

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Lingxi: Repository-Level Issue Resolution Framework Enhanced by Procedural Knowledge Guided Scaling

Yang Xu, Jiayuan Zhou, Michael Pacheco, Wenhan Zhu et autres

Driven by the advancements of Large Language Models (LLMs), LLM-powered agents are making significant improvements in software engineering tasks, yet struggle with complex, repository-level issue resolution. Existing agent-based methods have two key limitations. First, they lack of procedural knowledge (i.e., how an …

Influence of process parameters on the microstructure and mechanical property of Sapphire/Invar joints welded by femtosecond laser

Rui Kun Pan, Fuqiang Ye, Yinghao Feng, Pei Chen et autres

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Laser-free and low-jitter Electro-Optic Sampling of FEL-based THz radiation by intrinsic ultrafast laserlike-pulses at FLASH

Seung-gi Gang, Nicholas H. Matlis, Nikola Stojanovic, Rui Kun Pan

The FLASH1 THz beamline at DESY produces intense multicycle THz undulator radiation, along with quasi-single cycle edge radiation. Characterizing the temporal profile of THz radiation generated by free-electron lasers (FELs) is challenging due to unavoidable timing jitter between the THz pulse and …

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Subjective Perspectives within Learned Representations Predict High-Impact Innovation

Rui Kun Pan, James Evans

Existing studies of innovation emphasize the power of social structures to shape innovation capacity. Emerging machine learning approaches, however, enable us to model innovators' personal perspectives and interpersonal innovation opportunities as a function of their prior experience. We theorize and then quantify …

Modified conductive additives based on pine needle-derived biomass carbon for high-performance lithium-ion batteries

Hao Ge, Zhong-Hai Xiu, Rui Kun Pan, Bei Huang et autres

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Percival soft X-ray CMOS Imager for Photon Science – Status and Prospects

M. Hajheidari, C. Wunderer, Jonathan Correa, A. Marras et autres

Abstract Percival is a CMOS-based imager with 2 megapixels, also called P2M, designed for photon science experiments. The first generation of the P2M sensor showed some performance issues. Specifically, ADCs in full-speed operation mode are affected by crosstalk and show a non-linear …

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Placental RTN3L‐dependent ER‐Phagy Contributes to Fetal Testicular Dysplasia Upon Environmental Stress

Ye‐Xin Luo, Hua Zhu, Cheng Sun, Xinxin Zhang et autres

Prenatal environmental stress damages fetal testicular development, leading to male infertility. However, the precise mechanisms underlying the impact of gestational environmental stress on fetal testicular development require further investigation. This study demonstrates that gestational environmental stressor cadmium exposure caused placental estradiol synthesis …

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Advanced design strategies for enhancing the thermal stability of Ni-rich co-free cathodes towards high-energy power lithium-ion batteries

Hao Ge, Bei Huang, Rui Kun Pan, Xiaoman Cao et autres

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Advanced pseudocapacitive lithium titanate towards next-generation energy storage devices

Hao Ge, Rui Kun Pan, Bei Huang, Zhijia Sun et autres

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Electron thermalization and ion acceleration in XUV-produced plasma from nanoparticles in He gas environment

Eva Klimešová, Olena Kulyk, Lucas Janos Martin, Ulrike Frühling et autres

Abstract We use intense femtosecond extreme ultraviolet (XUV) pulses with a photon energy of 92 eV from the FLASH free electron laser to irradiate substrate-free CsCl nanoparticles surrounded by a He gas with a number density of around 1015 cm−3. By simultaneously …

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Theoretical and Experimental Study on Mpcvd Growth of Single Crystal Diamond with Different Crystal Orientations

Chaoyue Wang, Rui Kun Pan, Zeyang Ren, Jing Ning et autres

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