Hui Yang

Clinical evaluation of EUCAST rapid antimicrobial susceptibility testing in Gram-negative bacilli bloodstream infections: a real-world retrospective study

Peng-Peng Tian, Hua-Wei Yi, Tian Wang, Hui Yang et autres

Background/Objectives: Rapid antimicrobial susceptibility testing (RAST) performed directly from positive blood cultures may facilitate earlier optimization of antimicrobial therapy in bloodstream infections. In this single-center retrospective study, we evaluated the clinical performance of the EUCAST RAST method for Gram-negative bacilli bloodstream infections …

cn (code pays fourni par la source)

Estimating high spatiotemporal resolution XCO2 from multi-source satellite using a spatiotemporal stacking model

Yina Qiao, Hui Yang, Liu Cui, Yuan Zhang et autres

cn (code pays fourni par la source)

Antibacterial, In Vitro Anti-Inflammatory and Anti-Acne Activities of Patchouli Essential Oil

Jiabao Cui, Hui Yang, Chenglin Wang, Lingyi Liu et autres

Objectives: The study aimed to investigate the antibacterial, in vitro anti-inflammatory and anti-acne properties of Patchouli essential oil (PEO). Methods: PEO components were quantified by gas chromatography–mass spectrometry (GC-MS). The antibacterial activity of PEO against Cutibacterium acnes (C. acnes) and Staphylococcus epidermidis …

cn (code pays fourni par la source)

Nonlinear kernel-based high-dimensional inference for set-based genetic association studies

Zechen Zhang, Hui Yang, Meilin Zhu, Ran Guo et autres

Nonlinear genetic architectures, including epistasis and threshold effects, are increasingly recognized as contributors to complex disease risk, yet most existing SNP-set association tests rely on linear modeling assumptions, resulting in reduced power and unstable inference when genetic effects are nonlinear or heterogeneously …

cn, us (code pays fourni par la source)

Glutathione-depleting photosensitizers for tumor-specific imaging and pyroptosis-driven photodynamic therapy

Hui Yang, Yifei Yang, Zhengyumeng Zhu, Pei Chen et autres

Rationale: Selective initiation of pyroptosis in malignant cells can amplify the immunological benefits of photodynamic therapy (PDT), but conventional photosensitizers (PSs) often lack tumor specificity and require complex subcellular targeting motifs.Here we describe a glutathione (GSH)-responsive PDT platform based on PSs that …

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Integrating spaceborne BDS-R data from the Chinese Tianmu-1 constellation with SMOS freeze/thaw data product for soil state retrieval in the Arctic region: initial results using deep learning algorithms

Jinwei Bu, Qiulan Wang, Shaoqiang Fan, Hui Yang

cn, Rwanda (code pays fourni par la source)

tsRNADisease: a manually curated database of tsRNAs associated with human disease

Hui Yang, Huijun Wei, Wei Huang, Qi Chen et autres

tRNA-derived small RNAs (tsRNAs), as a class of regulatory small noncoding RNA, have been implicated in a wide variety of human diseases. Large amounts of tsRNA-disease associations have been identified in recent years from accumulating studies. However, repositories for cataloging the detailed …

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Identification of hub genes related to radiosensitivity and prognosis in rectal cancer

Hui Yang, Yin Liu, Mengdi Hao, Huimin Li et autres

Background: Radiotherapy is one of the main treatment methods for rectal cancer (RC). However, radioresistance often leads to treatment failure and poor prognosis. This study aimed to explore the core molecules associated with radiosensitivity and prognosis of RC. Methods: GSE133057 containing RC …

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Uncovering abnormal gray and white matter connectivity patterns in Alzheimer’s disease spectrum: a dynamic graph theory analysis for early detection

Juanjuan Jiang, Tao Kang, Ronghua Ling, Yingqian Liu et autres

Background Alzheimer’s disease (AD) requires early intervention at preclinical stages like subjective memory complaints (SMC). Traditional static brain network analyses lack sensitivity to detect early functional disruptions in SMC. This study aimed to improve preclinical AD stratification by integrating dynamic gray-white matter …

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Machine Learning Methods for Earth Observation and Remote Sensing Using Spaceborne GNSS Reflectometry: Current status, challenges, and future prospects

Jinwei Bu, Huan Li, Kegen Yu, Weimin Huang et autres

Spaceborne GNSS reflectometry (GNSS-R) missions have been successfully launched in recent years, such as Technology Demonstration Satellite (TDS-1) in 2014, Cyclone Global Navigation Satellite System (CYGNSS) in 2016, Bufeng (BF)-1 A/B in 2019, and Fengyun (FY)-3E/3F/3G and Tianmu-1, launched successively in 2021. …

cn, ca (code pays fourni par la source)

Comparative genomic and antimicrobial resistance profiles of Salmonella strains isolated from pork and human sources in Sichuan, China

Haojiang Zuo, Yang Yang, Mingming Su, Weifeng Huang et autres

Introduction Salmonella detection in retail pork is increasing, yet studies on its antimicrobial resistance (AMR) profiles and genomic characteristics remain limited. Moreover, it is still unclear whether certain Salmonella sequence types (STs) are consistently or rarely associated with pork as a transmission …

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The role of lactate and lactylation in ischemic cardiomyopathy: Mechanisms and gene expression

Mei Zhang, Xue Kong, Chenlu Wu, Jiu‐Hong Li et autres

Ischemic cardiomyopathy (ICM) is a significant global public health issue, with its pathophysiology encompassing atherosclerotic plaque formation, thrombosis, hypoperfusion, ischemic cell death, and left ventricular remodeling. Lactate is not only regarded as an energy metabolite but also acts as a signaling molecule …

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