Antonio Requena

The role of sperm DNA fragmentation in reproduction: a SWOT analysis

Joaquín Llácer, Antonio Requena, Miguel Ángel Checa, José Bellver et autres

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Mapping performance in 114,237 IVF cycles with donor oocytes reveals reproducible inefficiencies and distinct endophenotypes

Christian S. Ottolini, Francesca Mulas, Rebecca Cavagnola, Elvezia Maria Paraboschi et autres

Abstract Background In vitro fertilization (IVF) outcomes remain variable and difficult to predict, even in individuals without diagnosed infertility. This uncertainty complicates clinical decision-making and impedes the identification of biological factors that underlie IVF success or failure. A major barrier to progress …

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PGT-A Mosaicism Reporting Lacks Clinical Predictive Value: Evidence from a Multisite, Double-Blinded Study with Independent Validation Across 15,315 Single-Embryo Transfers

Patrick Gill, Xin Tao, Yiping Zhan, Fernando Mulas et autres

Abstract Preimplantation genetic testing for aneuploidy (PGT-A) aims to improve IVF outcomes by identifying embryos with lethal chromosomal abnormalities leading to impaired embryonic development and pregnancy loss, particularly with advancing maternal age. The adoption of next-generation sequencing (NGS) has enabled the detection …

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P-787 Obstetric and perinatal outcomes in pregnancies conceived after oocyte donation or trophoectoderm biopsy in women from 38 years old

Aleydah Salazar, A. Cejudo-Roman, J.M. Mascarós, M Cruz et autres

Abstract Study question Do oocyte donation (OD) or trophoectoderm biopsy for preimplantational genetic testing (TB-PGT) impact obstetric and perinatal outcomes in women ≥ 38 years old? Summary answer Women aged ≥38 years, particularly those using donor oocytes, have a moderate risk of …

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P-653 Medroxyprogesterone Acetate (MPA) vs GnRH Antagonist in oocyte donors' cycles with frozen eggs: insights into cumulative live birth rates

Antonio Cejudo-Román, J.M. Mascarós, Marı́a Esther Cruz, José Luís Merino et autres

Abstract Study question Is the cumulative live birth rate (CLBR) in oocyte donation cycles with frozen eggs comparable when pituitary suppression is performed with MPA versus GnRH antagonist? Summary answer The likelihood of achieving a live birth in oocyte donation cycles using …

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Three-dimensional ultrasound-based online system for automated ovarian follicle measurement

Pedro Royo, Elkin Muñoz, José-Enrique Romero, J. Manjon et autres

Ultrasound follicle tracking is an important part of cycle monitoring. OSIS Ovary (Online System for Image Segmentation for the Ovary) has been conceived aiming to aid the management of the workflow in follicle tracking, one of the most iterative procedures in cycle …

P-277 Focal rather than diffuse nature of adenomyosis might be more detrimental to IVF outcomes after single euploid embryo transfer

Rafael Trinchant, Mário Augusto Ferreira Cruz, Antonio Requena

Abstract Study question Is the nature of adenomyosis a factor to consider after a single euploid embryo transfer? Summary answer Focal adenomyosis was associated with lower live birth rate per transfer when compared to diffuse adenomyosis. What is known already Adenomyosis is …

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P-301 Real life experience with myolysis by radiofrequency in infertile patients with type 2 and 3 fibroids

Javier Martínez‐Salazar, C Fernandez, Alfredo Macías Vázquez, Pedro Royo et autres

Abstract Study question Can transvaginal radiofrequency myolysis (TVRF) be a safe alternative to reduce the fibroid volume without interfering with subsequent RA treatment? Summary answer RFTV myolysis is a safe and effective alternative for the treatment of type 2-3 uterine fibroids < …

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Corrigendum to ‘Medroxyprogesterone acetate: an alternative to GnRH-antagonist in oocyte vitrification for social fertility preservation and preimplantation genetic testing for aneuploidy’ Reproductive Biomedicine Online. 2023 Aug;47(2):103222

Juan Gilés, Mário Augusto Ferreira Cruz, A. Cobo, Carmen Vidal et autres

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Endometrial receptivity tests in reproduction: a SWOT analysis

Juan A. García-Velasco, Joaquín Llácer, Antonio Requena, Miguel Ángel Checa et autres

Endometrial receptivity and its management in assisted reproduction is now a significant focus of research interest. Endometrial receptivity tests, which analyze different panels of gene expression, are usually offered in fertility clinics to determine the women's individual 'window of implantation', providing a …

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Improving success rates by applying interventions in clinical practice and measuring their impact: A multicenter retrospective analysis of more than 240,000 cycles

Vanessa Vergara-Lozano, Nicolás Prados, María Cruz, Antonio Requena et autres

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Real-world practices of hormone monitoring during ovarian stimulation in assisted reproductive technology : a global online survey

Noémie Guedj, Roger Hart, Antonio Requena, V Vergara et autres

Objective: The aim of this study is to understand the global practice of routine hormonal monitoring (HM) during ovarian stimulation (OS) in the context of assisted reproductive technique (ART) treatment. Methods: An open-access questionnaire was available to 3,845 members of IVF-Worldwide.com from …

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