Wanli Lin

Circulating immune biomarkers indicate patients' immune imbalance and predict their severity and poor prognosis in pulmonary tuberculosis

Ling Yi, Sibo Long, Bin Yang, Y Xue et autres

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Comorbidity profiles of non-tuberculous mycobacteria infections in China: 12 years’ experience

Chao-hong Wang, Yiheng Shi, Bin Yang, Sibo Long et autres

ABSTRACT Nontuberculous mycobacteria (NTM) are of increasing public health concern. This study aimed to determine the most relevant comorbidities of NTM in Beijing, China, over a 12-year period. A retrospective analysis was performed on all 505 NTM patients diagnosed in Beijing Chest …

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Comparison of short-term outcomes of combined neoadjuvant chemotherapy and immunotherapy, neoadjuvant radiotherapy, and neoadjuvant chemotherapy for resectable locally advanced esophageal squamous cell carcinoma

Hai Zhang, Bei Wang, Bomeng Wu, Jiangbo Lin et autres

Background This study aimed to evaluate the safety and efficacy of neoadjuvant immunochemotherapy (nICT) compared to those of neoadjuvant chemoradiotherapy (nCRT) and neoadjuvant chemotherapy (nCT) in patients with locally advanced resectable esophageal squamous cell carcinoma (ESCC). Methods Patients with locally advanced resectable …

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Solid pseudopapillary neoplasm of the pancreas with elevated β-HCG levels: A case report

Minfen Zhang, Zhi Duan, Zhen Li, Jizhou He et autres

RATIONALE: Solid pseudopapillary neoplasm of the pancreas, first classified as a malignant epithelial tumor of the pancreas in 2019, is rare and usually occurs in young women, with a high incidence at approximately 30 years of age. Herein, we present a case …

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Soluble programmed cell death ligand-1 as a predictive biomarker for severity and poor prognosis in pulmonary tuberculosis

Xiaojue Wang, Wanli Lin, Sibo Long, Jun Yan et autres

Background We aimed to assess whether soluble programmed death-ligand 1 (sPD-L1) could serve as a new biomarker for PTB.Methods Plasma sPD-L1 levels in the discovery cohort were analyzed through flow cytometry and validated by sandwich ELISA. Pleural effusion sPD-L1 levels were measured …

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Analysis of the correlations between ultrasound-assessed diaphragm function and pulmonary function

Jiawei Huang, Li Cui, Bomeng Wu, Wanli Lin et autres

This study aimed to explore diaphragm parameters measurable using ultrasound and analyse their correlations with pulmonary function to comprehensively assess their clinical value. Patients diagnosed with pulmonary nodules or tumours at the thoracic surgery department of Gaozhou People’s Hospital between August 2023 …

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31P: Camrelizumab plus chemotherapy as first-line treatment for advanced non-squamous NSCLC with brain metastases: Final overall survival results from the CAP-BRAIN trial

Xiaohui Hou, Chenfei Zhou, Gang Wu, Wanli Lin et autres

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Higher 3-year recurrence-free survival rate in patients with complete pathological remission following neoadjuvant chemotherapy plus immunotherapy for esophageal cancer: a two-center, propensity score matching study

Hai Zhang, Haiquan He, Qingyi Feng, Bomeng Wu et autres

Background: Neoadjuvant therapy is preferentially recommended for resectable locally advanced esophageal malignancies, with patients who achieve pathological complete response (PCR) anticipated to have longer survival rates. The aim of this study was to compare 3-year follow-up data for patients with esophageal malignancy …

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Postoperative adjuvant immunotherapy for pathological stage II–IVa esophageal squamous cell carcinoma after radical surgery does not improve disease-free recurrence rates

Xihao Xie, Hai Zhang, Haiquan He, Bomeng Wu et autres

Background/objectives Postoperative adjuvant therapy for esophageal squamous cell carcinoma (ESCC) primarily includes chemotherapy and chemoradiotherapy. The survival benefits of postoperative adjuvant therapy for R0-resected ESCC remain controversial. Immunotherapy is being gradually applied perioperatively for esophageal cancer, but the efficacy of postoperative immunotherapy …

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Comparison of esophageal cancer survival after neoadjuvant chemoradiotherapy plus surgery versus definitive chemoradiotherapy: A systematic review and meta-analysis

Junli Ke, Yujie Xie, Shen-Yang Huang, Wei Wang et autres

Surgery after neoadjuvant chemoradiotherapy remains the gold standard for the treatment of resectable esophageal cancer (EC); however, chemoradiotherapy without surgery has been recommended in specific cases. The aim of this meta-analysis is to analyse the survival between surgeries after neoadjuvant chemoradiotherapy compared …

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Pan-mediastinal neoplasm diagnosis via nationwide federated learning: a multicentre cohort study

Ruijie Tang, Hengrui Liang, Yuchen Guo, Zhigang Li et autres

BACKGROUND: Mediastinal neoplasms are typical thoracic diseases with increasing incidence in the general global population and can lead to poor prognosis. In clinical practice, the mediastinum's complex anatomic structures and intertype confusion among different mediastinal neoplasm pathologies severely hinder accurate diagnosis. To …

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A revamped MIC-McKeown operation without removing azygos vein arch, bronchial artery and vagus nerve trunk

Hai Zhang, Ying Chen, Bomeng Wu, Ying Chen et autres

BACKGROUND: The purpose of this study was to investigate the effect of our revamped MIE-McKeown operation on postoperative gastrointestinal function recovery. METHODS: This revamped MIE-McKeown operation without removing azygos vein arch, bronchial artery and vagus nerve trunk and with the tubular stomach …

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