Jian Guang Qiu

Successful treatment with oxaliplatin and programmed cell death protein 1 inhibitor in recurrent advanced endometrial carcinoma with mismatch repair defects: a case report and literature review

Jian Guang Qiu, Tian Ding, Mingyue Cao, Xiaohong Huang et autres

The incidence of endometrial cancer (EC), a widely prevalent gynecological malignancy, is witnessing a global surge. Although early-stage cancer demonstrates promising outcomes, advanced cancer is associated with an unfavorable prognosis. Nevertheless, for specific pathological types or molecular subtypes of advanced EC, an …

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Targeted Next-Generation Sequencing for the Diagnosis of Gene Variants in Patients with 46,XY Disorder of Sex Development

Qiang Guo, Wen Wen Zhong, Hua Jian Lai, Lei Ye et autres

INTRODUCTION: Disorders of sex development (DSDs) are congenital abnormalities in which chromosomal, gonadal, and anatomical sex development are atypical. One of these disorders, 46,XY DSD, is particularly difficult to diagnose and manage because its etiology and clinical phenotypes are highly heterogeneous. METHODS: …

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Obstructive sleep apnea and cardiovascular events in acute coronary syndrome: a meta-analysis

Jiangtao Tong, Qian Yu, Yuan Li, Jianbo Du et autres

OBJECTIVE: Obstructive sleep apnea (OSA) in patients with the acute coronary syndrome (ACS) were at high risk for cardiovascular events, but the results are currently inconclusive. We aimed to conduct a systematic review to determine the incidence of cardiovascular events among ACS …

LncRNA-SNHG1 promotes paclitaxel resistance of gastric cancer cells through modulating the miR-216b-5p-hexokianse 2 axis

Jiewei Xu, Yongcan Xu, Guochao Ye, Jian Guang Qiu

Gastric cancer (GC) is one of the most malignant tumors with high incidence and poor prognosis. Currently, the combination of surgery with chemo- or radiotherapy is widely applied therapeutic strategy against GC. However, development of drug resistance severely limited the clinical application …

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Survival of Patients With Cervical Cancer Treated With Definitive Radiotherapy or Concurrent Chemoradiotherapy According to Histological Subtype: A Systematic Review and Meta-Analysis

Guorong Yao, Jian Guang Qiu, Fengjia Zhu, Xiaoxie Wang

Background: Cervical cancer is a leading cause of morbidity and mortality for women worldwide. Different histopathological cervical cancer subtypes (i.e., adenocarcinoma/adenosquamous carcinoma, and squamous cell carcinoma) are all treated similarly with definitive radiotherapy or concurrent chemoradiotherapy, but studies have reported differing survival …

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An Ovarian Large-Cell Neuroendocrine Carcinoma Accompanied by Clear Cell Carcinoma with Specific High Level of AFP: Case Report and Review of the Literature

Jian Guang Qiu, Guorong Yao, Feng Zhu, Yanyan Wang et autres

Abstract Background Large cell neuroendocrine carcinoma (LCNEC) is a rare histological subtype of ovarian cancer. A few cases have been reported in literature with high invasiveness and poor prognosis. However, there still have not accepted criteria for diagnosis and treatment of LCNEC. …

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MA16.03 CRISPR Screen Reveals XPO1 as a Therapeutic Target Strongly Sensitizing to First and Second Line Therapy in Small Cell Lung Cancer

Àlvaro Quintanal-Villalonga, Hiroki Taniguchi, Andrew S. C. Chow, Yi Zhan et autres

Collision carcinoma of endometrial adenocarcinoma and primary serous fallopian tube carcinoma: a case report

Yunfei Pan, Haihong Liao, Jian Guang Qiu, Yizhen Jiang et autres

Collision carcinoma is a rare malignancy that generally occurs in cervical, esophageal, pulmonary, and squamous cell cancers. Few studies have been reported involving endometrial adenocarcinoma and fallopian tube carcinoma. We reported the case of a 58-year-old woman who presented because of irregular …

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A mature cystic teratoma adherent to the vaginal wall: a case report

Jian Guang Qiu, Jiewei Xu, Guorong Yao, Mingyue Cao et autres

We present the case of a woman diagnosed with a teratoma adherent to the vaginal wall. The patient had been misdiagnosed with an ovarian teratoma 8 years previously at her local hospital, but no mass was found in the pelvic cavity during …

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Antitumor Activity of Cabazitaxel and MSC-TRAIL Derived Extracellular Vesicles in Drug-Resistant Oral Squamous Cell Carcinoma

Yong Qiu, Jianfang Sun, Jian Guang Qiu, Gang Chen et autres

Yongle Qiu,1 Jieming Sun,2 Junping Qiu,2 Guoling Chen,2 Xiao Wang,2 Yaxu Mu,2 Kunshan Li,1 Wenjing Wang1 1Department of Stomatology, Fourth Affiliated Hospital, Hebei Medical University, Shijiazhuang, Hebei 050017, People’s Republic of China; 2Department of Stomatology, Xianghe County People ‘S Hospital, Langfang, Hebei …

Serum Circular FoxO3a Serves as a Novel Prognostic Biomarker in Squamous Cervical Cancer

Xiang Dong Tang, Liu S, Yang Ding, Cheng Guo et autres

Xiaoyan Tang,1– 3,* Songping Liu,4,* Yan Ding,1– 3,* Chenyan Guo,1– 3 Jingjing Guo,1– 3 Keqin Hua,1– 3 Junjun Qiu1– 3 1Department of Gynecology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, People’s Republic of China; 2Department of Obstetrics and Gynecology of Shanghai …

COMPARISON OF PREDICTIVE MODELS FOR CONTRAST-INDUCED NEPHROPATHY FOLLOWING CORONARY ANGIOGRAPHY: A PROSPECTIVE MULTICENTER COHORT STUDY

Yong Liu, Zhiqiang Nie, Shiqun Chen, Xiaodong Zhuang et autres

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