Linda Chen

Efficacy and Toxicity of Triweekly Versus Weekly Cisplatin in Concurrent Chemoradiotherapy for Nasopharyngeal Carcinoma

Hao-Shen Cheng, Irini Yacoub, Winston Wong, Lara A. Dunn et autres

ABSTRACT This retrospective study compared the efficacy and toxicity of concurrent triweekly versus weekly cisplatin in patients with previously untreated, biopsy‐proven NPC who received definitive CRT followed by adjuvant chemotherapy. Patients with distant metastasis, Karnofsky Performance Status < 80, induction chemotherapy, or …

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CLTR-10 PHASE I/II STUDY OF STEREOTACTIC RADIOSURGERY WITH CONCURRENT OLAPARIB FOLLOWED BY ADJUVANT DURVALUMAB AND PHYSICIAN’S CHOICE SYSTEMIC THERAPY IN SUBJECTS WITH BREAST CANCER BRAIN METASTASES (SOLARA)

Colette Shen, Yara Abdou, Linda Chen, Mina Lobbous et autres

Abstract Purpose Outcomes for patients with HER2-negative breast cancer with brain metastases remain poor. Therapeutic strategies that enhance radiation-induced DNA damage and anti-tumor immune response may improve intracranial control. We evaluated toxicity and intracranial disease control in patients receiving combination stereotactic radiosurgery …

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Small sharp spikes precede the development of epileptiform discharges in temporal lobe epilepsy

Lianping Xu, Shasha Wu, Sandra Rose, Linda Chen et autres

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CO166 INCREASED RISK OF DIABETIC KETOACIDOSIS IN ADULTS WITH DELAYED DIAGNOSIS OF TYPE 1 DIABETES

Da Sol Kim, Linda Chen, Timothy Reynolds, Paul Godley

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MT4 ADOPTION OF PSMA-PET IMAGING FOR PROSTATE CANCER WITHIN A LARGE INTEGRATED HEALTH SYSTEM, 2021-2024

Michael R. McGovern, Timothy Reynolds, Linda Chen, Da Sol Kim et autres

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MSR165 USE ARTIFICIAL INTELLIGENCE TO PREDICT REGULATORY APPROVAL BASED ON PHASE III ONCOLOGY CLINICAL TRIAL PUBLICATIONS

Beverly Fuerte, Da Sol Kim, Kenneth Youens, Timothy Reynolds et autres

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A phase II, multicenter, single-arm clinical trial of response-adapted definitive radiotherapy and cemiplimab-rwlc immunotherapy for locally advanced, unresectable cutaneous squamous cell carcinoma: RAMPART.

Christopher Andrew Barker, Ryan Michael Lanning, Shlomo A. Koyfman, Jay Justin Liao et autres

9506 Background: Locally advanced (T3-4/N+/M0) and unresectable cutaneous squamous cell carcinoma (LAUCSCC) patients (pts) have been historically treated with definitive radiotherapy (RT) +/- chemotherapy, yielding poor outcomes (18m progression-free survival [PFS] rates of ~38%). More recently, anti-PD1 immunotherapy with cemiplimab (cemi) led …

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Cognitive Modes Detectable by fMRI during the Sternberg Task

Erica Zeng, Linda Chen, Eva Feredoes, John Shahki et autres

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Eligibility for redirection from the pediatric emergency department: a qualitative study of professional and leader perspectives

Erica Qureshi, Quynh Doan, Linda Chen, Garth D. Meckler et autres

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Osteoradionecrosis After Intensity-Modulated Radiation Therapy or Proton Therapy in Oropharyngeal Carcinoma

Fan Yang, Edward Christopher Dee, Annu Singh, Yingzhi Wu et autres

Importance: Osteoradionecrosis (ORN) is a potentially debilitating late complication of radiotherapy (RT) for head and neck cancer. While proton therapy offers superior dose conformality, its impact on ORN risk remains uncertain, particularly in patients with oropharyngeal squamous cell carcinoma (OPSCC). Objective: To …

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Real-world chronic lymphocytic leukemia (CLL)–specific biomarker testing patterns and frontline treatment patterns in patients with CLL/small lymphocytic lymphoma (SLL)

Tim Reynolds, William Ye, Linda Chen, Mohammad Reza Eskandari et autres

Abstract Introduction: CLL/SLL is the most common leukemia in adults in the United States, with ~21,000 cases diagnosed annually. National Comprehensive Cancer Network (NCCN) guidelines recommend testing for certain prognostic variables prior to initiation of CLL/SLL treatment (tx). For patients (pts) with …

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The Use of Proton Radiation in the Management of Adenoid Cystic Carcinoma

Irini Ihab Yacoub, Achraf A. Shamseddine, Daniel Kallini, Nader Mohamed et autres

Purpose/Objectives: Adenoid cystic carcinoma (ACC) of the head and neck is a rare malignancy with a prolonged but infiltrative course, marked by perineural invasion and high risk of local recurrence and distant metastases. The standard of care for head/neck ACC is surgery …

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