A. Gintsburg

Single-Dose Intranasal or Intramuscular Administration of Simian Adenovirus-Based H1N1 Vaccine Induces a Robust Humoral Response and Complete Protection in Mice

Daria V. Voronina, Irina V. Vavilova, Olga V. Zubkova, Tatiana A. Ozharovskaia et autres

Despite the widespread accessibility of vaccines and antivirals, seasonal influenza virus epidemics continue to pose a threat to public health. In this study, we constructed a recombinant replication-deficient simian adenovirus type 25 vector carrying the full-length hemagglutinin (HA) of the H1N1 influenza …

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Preparation and Crystallographic Analysis of a Complex of SARS-CoV-2 S-Protein Receptor-Binding Domain with a Virus-Neutralizing Nanoantibody

Konstantin M. Boyko, Larisa A. Varfolomeeva, Nikita A. Egorkin, Mikhail E. Minyaev et autres

Abstract Coronavirus SARS-CoV-2 was the cause of global pandemic COVID-19 that has claimed millions of lives around the world. One of the approaches to the therapy of severe forms of COVID-19 is based on the use of virus-neutralizing antibodies against the receptor-binding …

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Single-Domain Antibodies Efficiently Neutralize SARS-CoV-2 Variants of Concern

I. A. FAVORSKAYA, Dmitry V. Shcheblyakov, I. B. Esmagambetov, Inna V. Dolzhikova et autres

Virus-neutralizing antibodies are one of the few treatment options for COVID-19. The evolution of SARS-CoV-2 virus has led to the emergence of virus variants with reduced sensitivity to some antibody-based therapies. The development of potent antibodies with a broad spectrum of neutralizing …

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Single-domain antibodies efficiently neutralize SARS-CoV-2 variants of concern, including Omicron variant

I. A. FAVORSKAYA, Dmitry V. Shcheblyakov, I. B. Esmagambetov, Inna V. Dolzhikova et autres

ABSTRACT Virus-neutralizing antibodies are one of the few treatment options for COVID-19. The evolution of SARS-CoV-2 virus has led to the emergence of virus variants with reduced sensitivity to some antibody-based therapies. The development of potent antibodies with a broad spectrum of …

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P157 Monitoring the distribution and genotypic diversity of Burkholderiales bacteria in Russian cystic fibrosis patients in the year of the COVID-19 pandemic

Olga L. Voronina, Н. Н. Рыжова, Marina S. Kunda, Ekaterina I. Aksenova et autres

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P143 Nasal sinuses and lung microbiome in cystic fibrosis patients

Olga L. Voronina, Н. Н. Рыжова, Marina S. Kunda, Н. Е. Шарапова et autres

RESPIRATORY TRACT MICROBIOME IN CHILDREN WITH CYSTIC FIBROSIS

Н. Н. Рыжова, Olga L. Voronina, E. V. Loseva, Ekaterina I. Aksenova et autres

МИКРОБИОМ РЕСПИРАТОРНОГО ТРАКТА ДЕТЕЙ С МУКОВИСЦИДОЗОМ Н. Н. Рыжова 1 , О. Л. Воронина 1 , Э. В. Лосева 2 , е. И. Аксенова 1 , М. С. Кунда 1 , Н. е.Шарапова 1 , В. Д. Шерман 3 , А. Л. …

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Использование гликопротеина GP для создания универсальной вакцины против лихорадки Эбола

Inna V. Dolzhikova, Amir I. Tukhvatulin, Anastasia S. Gromova, Daria M. Grousova et autres

Болезнь, вызванная вирусом Эбола (БВВЭ) — одно из самых высоколетальных вирусных заболеваний, поражающих человека и приматов. Возбудителем БВВЭ является вирус Эбола. В настоящее время известно шесть видов этого вируса, три из них патогенны для человека — это виды Заир (ZEBOV), Судан (SUDV) …

Novel Polycationic Photosensitizers for Antibacterial Photodynamic Therapy

Г. А. Меерович, E. V. Akhlyustina, И. Г. Тиганова, E. A. LUK'YANETS et autres

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P069 Changes in airways bacterial community with cystic fibrosis patients’ age and lung function decline

Olga L. Voronina, Н. Н. Рыжова, Marina S. Kunda, Н. Е. Шарапова et autres

123 Emerging Burkholdriales bacterium in lung disease

Olga L. Voronina, Н. Н. Рыжова, Marina S. Kunda, Ekaterina I. Aksenova et autres

125 Airways bacterial community composition in assessing the results of antibacterial therapy

Olga L. Voronina, Н. Н. Рыжова, M Kunda, E. Amelina et autres