Yang Hao

Computational Modeling of PI3K/AKT Pathway in Bipolar Disorder and Type 2 Diabetes: Implications for Lithium Treatment and Curcumin as a Potential Alternative

Jing Li, Wenqing Wang, Yajunzi Wang, Yang Hao et autres

Bipolar disorder (BD) exhibits a high comorbidity rate with type 2 diabetes (T2D), suggesting shared pathophysiological mechanisms. Although lithium serves as the first-line treatment for BD, its underlying therapeutic mechanism and potential effects on T2D remain incompletely understood. This study identified the …

gb, cn (code pays fourni par la source)

Oncolytic virus for cancer immunotherapy

Penghui Yang, Yang Hao

cn (code pays fourni par la source)

The Role and Clinical Relevance of Glycolysis‐Associated Genes on Immune Infiltration in Hepatocellular Carcinoma

Jing Li, Peng Su, Ting Li, Yang Hao et autres

Hepatocellular carcinoma (HCC) poses a significant challenge with dismal survival rates, necessitating a deeper understanding of its molecular mechanisms and the development of improved therapies. Metabolic reprogramming, particularly heightened glycolysis, plays a crucial role in HCC progression. Glycolysis-associated genes (GAGs) emerge as …

gb, cn, us (code pays fourni par la source)

An Engineered Influenza a Virus Expressing the Co-Stimulator OX40L as an Oncolytic Agent Against Hepatocellular Carcinoma

Yang Hao, Guanglin Lei, Zhuoya Deng, Fang Sun et autres

Background: Oncolytic virus (OV) therapy has emerged as a promising novel form of immunotherapy. Moreover, an increasing number of studies have shown that the therapeutic efficacy of OV can be further improved by arming OVs with immune-stimulating molecules. Methods: In this study, …

cn (code pays fourni par la source)

Measurement of the $e^+e^-\to\pi^+\pi^-\pi^0$ Cross Section from 0.7 GeV to 3.0 GeV via Initial-State Radiation

F. De Mori, H. X. Yang, M. Kuemmel, Z.P. Zhang et autres

The cross section of the process $e^+e^-\to\pi^+\pi^-\pi^0$ is measured with a precision of 1.6% to 25% in the energy range between $0.7$ and 3.0 GeV using the Initial State Radiation method. A data set with an integrated luminosity of $2.93$fb$^{-1}$ taken at …