Junoh Kim

Scale-up production of Dunaliella salina extracellular vesicle-mimetics by mechanical processing: Physicochemical and functional comparison with natural extracellular vesicles

Hee Jung Shin, Jihoon Kim, Jaehwa Hong, Youngeun Ji et autres

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Label-free and real-time monitoring of photoaging with high spatiotemporal resolution using an nIR fluorescent nanosensor array

Youngwook Cho, Hwira Baek, Damee Koh, Changyu Tian et autres

Reactive oxygen species (ROS) bursts from photoaging cause skin damage and chronic conditions. Understanding spatiotemporal ROS dynamics is critical for developing therapies and cosmetic strategies to enhance skin health. Conventional assays and fluorescence microscopy lack the resolution for real-time ROS quantification due …

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Anti‐melanogenic effects of Medicago sativa seed extracts on melanocytes

Chae Rin Kim, Jung Hyun Woo, Min‐Ah Choi, Hee Jung Shin et autres

OBJECTIVE: Alfalfa (Medicago sativa) is a prominent herbal treatment among Asian countries and its antioxidant and anti-inflammatory effects have already been generally elucidated. Excessive melanin synthesis is one of the major troubles in the cosmetics industry, thus such research has been extensively …

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Iris germanica L. Rhizome-Derived Exosomes Ameliorated Dihydrotestosterone-Damaged Human Follicle Dermal Papilla Cells Through the Activation of Wnt/β-Catenin Pathway

Mujun Kim, Jung Hyun Woo, Jinsick Kim, Min‐Ah Choi et autres

Hair loss is often associated with oxidative stress and mitochondrial dysfunction in human follicle dermal papilla cells (HFDPCs), resulting in impaired cellular function and follicle degeneration. Thus, many studies have been conducted on natural plants aimed at inhibiting hair loss. This study …

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Microalgae-Derived Microparticles Improve Immunomodulation via Combined Glycolysis and MAPK Activation

Hwira Baek, Seul‐Gi Kim, Young-Seok Kim, Junoh Kim et autres

Natural polysaccharides possess potent immunostimulatory properties, but their poor solubility impedes efficiency of cellular delivery. This study focuses on extraction of microparticles (MPs) from Euglena gracilis, a microalgae species characterized by abundant intracellular β-1,3-glucan and flexible cell membrane. We introduce an E. …

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Hydrolyzed cow colostrum extract (BCFM) inhibits alpha-MSH-induced melanogenesis in B16F1 cells via regulation of the MC1R-cAMP signaling pathway

Jae Hyeok Choi, Taeil Kwak, Hee-Jung Shin, Yang Hee Jo et autres

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Hydrolyzed Cow Colostrum Extract (BCFM) Inhibits Alpha-MSH-Induced Melanogenesis in B16F1 Cells via Regulation of the MC1R-cAMP Signaling Pathway

Jae Hyeok Choi, Taeil Kwak, Hee Jung Shin, Yang Hee Jo et autres

us, gb (code pays fourni par la source)

Fermented black ginseng extract prevents UVB ‐induced inflammation by regulating the nc886‐PKR pathway in human keratinocytes

Yuna Kim, J. A. Sim, Kyungeun Jeon, Dehun Ryu et autres

Abstract Background Continuous exposure of the skin to ultraviolet B (UVB) rays can cause inflammation and photodamage. In previous studies, we observed that the upregulation of nc886, a noncoding RNA (ncRNA), can alleviate UVB‐induced inflammation through suppression of the protein kinase RNA …

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Protective Effect of Iris germanica L. Rhizome-Derived Exosome against Oxidative-Stress-Induced Cellular Senescence in Human Epidermal Keratinocytes

Ji‐Seon Kim, Hyun‐Jeong Lee, Eun-Jeong Yoon, Hyunsang Lee et autres

Plant-derived exosomes can exert therapeutic effects against various dermatological conditions. Several studies have demonstrated that plant-derived exosomes can have positive effects on the skin, preventing aging, hyperpigmentation, and hair loss. In this study, the protective effects of Iris germanica L. rhizome-derived exosomes …

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Nonanimal Euglena gracilis‐Derived Extracellular Vesicles Enhance Skin‐Regenerative Wound Healing (Adv. Mater. Interfaces 4/2023)

Yuri Ko, Hwira Baek, Jee‐Hyun Hwang, Young-Seok Kim et autres

Skin Regeneration Technology In article number 2202255, Kyung-Min Lim, Junoh Kim, Jin Woong Kim, and colleagues report a skin regeneration technology by taking advantage of Euglena gracilis (EG)-derived extracellular microvesicles (EMVEG). They show that the EMVEG system enables the design of new …

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Nonanimal Euglena gracilis‐Derived Extracellular Vesicles Enhance Skin‐Regenerative Wound Healing

Yuri Ko, Hwira Baek, Jee‐Hyun Hwang, Young-Seok Kim et autres

Abstract This study proposes using microalgae‐containing carbohydrate bioactives, an Euglena gracilis‐derived extracellular microvesicle (EMVEG) system, for enhanced skin regeneration. The critical deformation ratio, 1.67, during cell extrusion enables the authors to tune the particle size of the EMVEG at ≈1 µm, thus …

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The protective effect of alfalfa (Medicago sativa L.) seed extract containing polysaccharides on human keratinocytes and fibroblasts

Jeeyoung Kim, Weon Jeong Bang, Jung Soo Woo, Younghwa Kim et autres

To protect the body against environmental threats, cosmetics can play important antiinflammatory and anti-aging roles. Many researchers have developed cosmetic ingredients using natural plant extracts or the active compounds of such extracts. In this study, we assessed the ability of extracts from …

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