Yan Geng

Interferon-induced Protein 44-like Promoter Hypomethylation as an Epigenetic Hallmark of Systemic Lupus Erythematosus

Xiaohui Zhang, Yong Fan, Lanlan Ji, Di Gao et autres

cn (code pays fourni par la source)

MTPC integration for improved diagnosis of pleural effusion

Shuai Zhao, J. Q. Liu, Jing Chen, Ji Shi et autres

Introduction: Pleural effusion is clinically common with diverse etiologies, and differentiating benign from malignant cases is critical for treatment planning and prognosis assessment. Traditional single diagnostic methods have inherent limitations, leading to diagnostic challenges. This study aimed to develop a multi-modal diagnostic …

cn (code pays fourni par la source)

Diacetyl-induced bronchiolitis obliterans involves ubiquitin C upregulation and fibrosis-related gene activation in rats

Hailian Wang, Wen Jiang, Yan Geng, Qing Ye et autres

Introduction: Bronchiolitis obliterans (BO) is an irreversible, chronic obstructive pulmonary disease with inflammation and fibrosis causing bronchiolar narrowing. Inhaling diacetyl (DA) can result in BO in humans. Methods: We aimed to investigate the relationship between fibrosis-related gene expression and ubiquitin C (UbC) …

cn (code pays fourni par la source)

Characterization of OXA-1224, a novel OXA-213-like β-lactamase encoded by the chromosome of Acinetobacter pittii

Zeshi Liu, Siquan Shen, Jing Lei, Shuai Zhao et autres

cn (code pays fourni par la source)

Purification, Structural Analysis and Bioactivity of Pueraria montana Polysaccharide

Dandan Chen, Hongliang Yao, Xiang Qiu, Xu Lang et autres

Pueraria montana is a medicinal and edible plant widely distributed in Asia. It has antipyretic, analgesic, and anti-inflammatory properties. In this study, a novel polysaccharide (PMPS-A1) was obtained through purification, and its biological activity was investigated. Structural analysis revealed that PMPS-A1 was …

cn (code pays fourni par la source)

Anti-inflammatory activity and underlying mechanism against sepsis-induced acute lung injury of a low-molecular-weight polysaccharide from the root of Stemona tuberosa Lour

Xiang Qiu, Yan Geng, Xiaoyue Cai, Yanghui Ou et autres

The root of Stemona tuberosa Lour has been used to treat tuberculosis, scabies, and eczema. Polysaccharides are among its main bioactive ingredients. A low-molecular-weight (1819 Da) polysaccharide (SPS2-A) was obtained from the root of S. tuberosa Lour by optimizing three-phase partitioning, purified …

cn (code pays fourni par la source)

Durable Clinical Response to ALK Tyrosine Kinase Inhibitors in Epithelioid Inflammatory Myofibroblastic Sarcoma Harboring PRRC2B-ALK Rearrangement: A Case Report

Zhan Wang, Yan Geng, Lingyan Yuan, Miaomiao Wang et autres

Inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal neoplasm and patients with IMT tend to have a favorable outcome after complete surgical resection. However, some tumors of IMT cases have recurred and grown rapidly after successful surgery. Epithelioid inflammatory myofibroblastic sarcoma (EIMS) …

cn (code pays fourni par la source)

Identification of potential key genes in anaplastic thyroid cancer using bioinformatics analysis

Zhenzhen Li, Chaoliang Xiong, Jin Wei, Ping Chen et autres

Anaplastic thyroid cancer (ATC) has a high degree of malignancy and poor prognosis. The purpose of this study was to determine differentially expressed genes (DEGs) in ATC through biometric analysis technology, clarify potential interactions between them, and screen genes related to the …

Erythropoietin as a Potential Prognostic Biomarker Correlated With Immune Infiltration in Hepatocellular Carcinoma

Huange Zhu, Yanping Zhang, Jiafeng Yin, Jie Lu et autres

Abstract Background. Hepatocellular carcinoma (HCC) is a malignant tumor with poor prognosis. Immune checkpoint genes are considered novel tumor immunotherapy targets for many cancer types. Erythropoietin (EPO) is a protein secreted mainly in the liver and kidneys; in several cancer types, EPO …

cn (code pays fourni par la source)

Impact of Allogeneic Leukocyte-Depleted Red Blood Cell Transfusion on Inflammatory Response and Blood Coagulation in Patients with Recurrence of Colon Cancer after Operation

Yan Geng, Liyan Liu

OBJECTIVE: Anemia inevitably affects the survival of cancer patients. In clinical practice, patients with anemia and decreased blood volume are treated by component blood transfusion. Through targeted blood transfusion therapy, the efficacy of blood transfusion treatment can be validly improved, which renders …

cn (code pays fourni par la source)

Identification of potential key genes in anaplastic thyroid cancer using bioinformatics analysis

Zhenzhen Li, Jin Wei, Ping Chen, Yanping Zhang et autres

Abstract Background Anaplastic thyroid cancer (ATC) has a high degree of malignancy and a poor prognosis. Its incidence accounts for approximately 10–15% of all thyroid cancers. The purpose of this study was to determine the differentially expressed genes (DEGs) of ATC through …

cn, th (code pays fourni par la source)

Identification of Potential Key Genes in Anaplastic Thyroid Cancer Using Bioinformatics AnalysisIdentification of Potential Key Genes in Anaplastic Thyroid Cancer using Bioinformatics Analysis

Zhenzhen Li, Chaoliang Xiong, Jin Wei, Ping Chen et autres

cn (code pays fourni par la source)