Accès ouvert
2026
article
OpenAlex
José A. Núñez-López, David Molina-García, José Luis González-Fernández
Manipulative materials are widely considered valuable resources in geometry education because they may support visualization, spatial reasoning, and conceptual understanding when implemented within appropriate instructional contexts. However, many existing resources focus on isolated concepts and provide limited opportunities for connecting geometric relationships …
es
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Accès ouvert
2026
article
OpenAlex
Shreya Gandhi, Beatriz Ocaña-Tienda, Manuel M. Bettencourt, O Singh et autres
Background: Glioblastoma (GB) exhibits marked tumor microenvironmental heterogeneity, contributing to both therapy resistance and poor survival outcomes. Intercellular adhesion molecule 1 (ICAM1) is an inflammation-associated adhesion molecule implicated in immune-stromal interactions, but its clinical and biological significance in GB remains incompletely defined. …
us, es, ca, au
(code pays fourni par la source)
Accès ouvert
2025
preprint
OpenAlex
Jesús J. Bosque, David Molina-García, Julián Pérez-Beteta, A. Vicente et autres
ABSTRACT OBJECTIVE The normalised distance from the metabolic hotspot to the tumour centroid (NHOC) in Positron Emission Tomography (PET) scans is an imaging biomarker previously shown to have prognostic value in non-small cell lung cancer (NSCLC) and breast cancer (BC). The primary …
es
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Accès ouvert
2025
article
OpenAlex
José Luis González-Fernández, David Molina-García, José Antonio Núñez-López
El presente estudio tiene como objetivo principal analizar el impacto de la eliminación de las calculadoras gráficas en las pruebas de acceso a la universidad de Matemáticas II en Castilla-La Mancha durante los cursos 2021-22, 2022-23 y 2023-24. A través de una …
es
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Accès ouvert
2024
article
OpenAlex
José Antonio Núñez-López, David Molina-García, José Luis González-Fernández, Iván Fernández-Suárez
Introducing initial algebraic principles poses a significant challenge, often compounded by the inherent abstract nature of algebra. This article introduces an innovative pedagogical approach that promotes the use of algebra tiles, a didactic manipulative material formed by a collection of geometric pieces …
es
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Accès ouvert
2023
article
OpenAlex
Beatriz Ocaña-Tienda, Julián Pérez-Beteta, Juan Jiménez-Sánchez, David Molina-García et autres
Tumor growth is the result of the interplay of complex biological processes in huge numbers of individual cells living in changing environments. Effective simple mathematical laws have been shown to describe tumor growth in vitro, or simple animal models with bounded-growth dynamics …
es
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Accès ouvert
2023
data-paper
OpenAlex
Beatriz Ocaña-Tienda, Julián Pérez-Beteta, José Villanueva-García, José Romero-Rosales et autres
Brain metastasis (BM) is one of the main complications of many cancers, and the most frequent malignancy of the central nervous system. Imaging studies of BMs are routinely used for diagnosis of disease, treatment planning and follow-up. Artificial Intelligence (AI) has great …
es
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Accès ouvert
2023
article
OpenAlex
Jesús J. Bosque, Gabriel F. Calvo, David Molina-García, Julián Pérez-Beteta et autres
Different evolutionary processes push cancers to increasingly aggressive behaviors, energetically sustained by metabolic reprogramming. The collective signature emerging from this transition is macroscopically displayed by positron emission tomography (PET). In fact, the most readily PET measure, the maximum standardized uptake value (SUV …
es
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Accès ouvert
2023
dataset
OpenAlex
Beatriz Ocaña Tienda, Julián Pérez-Beteta, José Romero-Rosales, David Molina-García et autres
First set of DICOM files
ch
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Accès ouvert
2023
dataset
OpenAlex
Beatriz Ocaña Tienda, Julián Pérez-Beteta, José Romero-Rosales, David Molina-García et autres
Images in nifti format
ch
(code pays fourni par la source)
Accès ouvert
2023
dataset
OpenAlex
Beatriz Ocaña Tienda, Julián Pérez-Beteta, José Romero-Rosales, David Molina-García et autres
Third set of DICOM files
ch
(code pays fourni par la source)
Accès ouvert
2023
dataset
OpenAlex
Beatriz Ocaña Tienda, Julián Pérez-Beteta, José Romero-Rosales, David Molina-García et autres
Morphological measurements of annotated brain metastases
ch
(code pays fourni par la source)