Cláudia C. Faria

Correction to “Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression”

João Conde, Ruth A. Pumroy, Charlotte Baker, Tiago Rodrigues et autres

GIMM CARE Strategic Research and Innovation Agenda 2026-2029

Cristovão M. Sousa, Laura Ward, Gulbenkian Institute for Molecular Medicine, Madalena Gil Martins Reis et autres

This document outlines GIMM CARE’s short- and medium-term strategic priorities, detailing selected disease-specific missions, key research and innovation actions, open calls for collaboration, and priorities for research infrastructure capacitation, integrating next-generation technologies. Co-created with the GIMM CARE Direction and management teams, CARE …

us, pt, es (code pays fourni par la source)

GIMM CARE Strategic Research and Innovation Agenda 2026-2029

Cristovão M. Sousa, Laura Ward, Gulbenkian Institute for Molecular Medicine, Madalena Gil Martins Reis et autres

This document outlines GIMM CARE’s short- and medium-term strategic priorities, detailing selected disease-specific missions, key research and innovation actions, open calls for collaboration, and priorities for research infrastructure capacitation, integrating next-generation technologies. Co-created with the GIMM CARE Direction and management teams, CARE …

us, pt, es (code pays fourni par la source)

Questions of the future in aging and longevity research at the GIMM Festival

Laura Ward, Cláudia C. Faria, Maria M. Mota, João Pedro de Magalhães et autres

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Questions of the future in aging and longevity research at the GIMM Festival

Laura Ward, Cláudia C. Faria, Maria M. Mota, João Pedro de Magalhães et autres

us, pt, gb, sg, fr (code pays fourni par la source)

Questions of the future in aging and longevity research at the GIMM Festival

Laura Ward, Cláudia C. Faria, Maria M. Mota, João Pedro de Magalhães et autres

us, pt, gb, sg, fr (code pays fourni par la source)

circNTRK2 protects NTRK2 expression in the distinct biological pilocytic astrocytoma subgroup 2

Daniel Picard, Michelle Bleimehl, F Wentzel, Nan Qin et autres

Pilocytic astrocytoma (PA), the most common pediatric brain tumor, is primarily driven by aberrant mitogen-activated protein kinase (MAPK) signaling, most often due to BRAF gene fusions or activating mutations. While the five-year overall survival rate exceeds 95%, recurrence or progression remains a …

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EP10.03 ASSESSING INTEREST IN THE SIOPE BTG YOUNG INVESTIGATORS AND INNOVATORS (YII) GROUP: RESULTS FROM A EUROPEAN SURVEY

Camilla Satragno, John Apps, Enrico Opocher, C Michi et autres

Abstract BACKGROUND To support the growing interest in structured collaboration among young researchers, the SIOPE BTG Young Investigators and Innovators (YII) Group initiated a new phase of development. To guide this process and assess community needs, we conducted a dedicated survey among …

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MON-066 Overcoming Cabergoline Resistance in a Macroprolactinoma: Diagnostic and Therapeutic Challenges

Marta Vaz Lopes, José Vicente Rocha, Mariana de Griné Severino, Carolina Ribeiro Peixe et autres

Abstract Disclosure: M.V. Lopes: None. J. Rocha: None. M.D. Severino: None. C.R. Peixe: None. C.I. Lopes: None. M. Duarte: None. M.I. Alexandre: None. A. Gomes: None. C.C. Faria: None. E.L. Nobre: None. Introduction: Dopamine agonists (DA), particularly cabergoline, are effective in treating …

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SAVANA: reliable analysis of somatic structural variants and copy number aberrations using long-read sequencing

Hillary Elrick, Carolin M. Sauer, Jose Espejo Valle-Inclán, Katherine Trevers et autres

Accurate detection of somatic structural variants (SVs) and somatic copy number aberrations (SCNAs) is critical to study the mutational processes underpinning cancer evolution. Here we describe SAVANA, an algorithm designed to detect somatic SVs and SCNAs at single-haplotype resolution and estimate tumor …

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Unlocking the Role of Metabolic Pathways in Brain Metastatic Disease

M. R. Pinto, Sara Violante, Rita Cascão, Cláudia C. Faria

The dissemination of malignant cells to the brain is a late-stage complication of cancer, leading to significant morbidity and mortality. Brain metastases (BM) affect 20-30% of cancer patients, primarily originating from lung cancer, breast cancer, and melanoma. Despite advances in molecular-targeted therapies, …

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Primary intraosseous cavernous hemangioma of the clivus in a pediatric patient: A case report and review of the literature

Jessica Branco, Samuel Sequeira Lemos, Vitor Oliveira, Cláudia C. Faria

Background: Primary intraosseous cavernous hemangiomas (PICH) of the skull are rare, benign, vascular tumors mainly found in adults' calvarium. Affection of the clivus has been reported, with the most frequent clinical presentation being headaches followed by cranial nerve compromise. In the pediatric …

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