Jinyao Zhang

GSTK1 suppresses HCC aggravation via L-carnitine metabolism by PGAM5/DRP1 complex-mediated mitochondrial quality control

Yuze Shi, Jinyao Zhang, Haitian Zhang, Jianbo He et autres

BACKGROUND: Hepatocellular carcinoma (HCC) is among the leading causes of cancer-related mortality worldwide. The high recurrence rate and resistance to chemotherapy of HCC contribute to poor clinical outcomes, necessitating the development of novel therapeutic strategies. Glutathione S-transferase kappa 1 (GSTK1) is specifically …

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Molecular mechanism underlying radiation resistance in esophageal squamous cell carcinoma

Gang Ran, Mao Hu, Jinyao Zhang, Wenkun Zhu et autres

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Targeting xanthine oxidoreductase reverses resistance to EGFR tyrosine kinase inhibitors in intrahepatic cholangiocarcinoma

Jianbo He, Minglu Zhang, Yuze Shi, Zetao Ji et autres

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High-efficient immobilization of uranium by biochar loaded mixed microorganisms composed of Bacillus and Pseudomonas

Jinyao Zhang, Nan Li, Xingrong Guo, Xueqin Li et autres

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Efficacy in patients with EGFR -positive non-small-cell lung cancer treated with dacomitinib who had skin adverse events: post hoc analyses from ARCHER 1050

Xingxiang Pu, Juan Li, Bo Zhang, Jinyao Zhang et autres

Aim: We investigated association between skin adverse events (AEs) and efficacy with dacomitinib in patients with EGFR-positive non-small-cell lung cancer (NSCLC).Methods: Post hoc analyses from ARCHER 1050 evaluated efficacy in patients who did and did not experience grade ≥2 skin AEs with …

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Improving Resistance of Mango to Colletotrichum gloeosporioides by Activating Reactive Oxygen Species and Phenylpropane Metabolism of Bacillus amyloliquefaciens GSBa-1

Wenya Li, Hua Chen, Jianhu Cheng, Min Zhang et autres

This study aimed to explore the effects of Bacillus amyloliquefaciens GSBa-1 treatment on anthracnose disease resistance and the metabolism of reactive oxygen species (ROS) and phenylpropanoids in mangoes during storage. Mangoes were soaked in a solution containing 1 × 108 CFU/mL of …

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Excess multi-cause mortality linked to influenza virus infection in China, 2012–2021: a population-based study

Tian-Lu Yin, Ning Chen, Jinyao Zhang, Shuang Yang et autres

Objectives: The aim of this study is to estimate the excess mortality burden of influenza virus infection in China from 2012 to 2021, with a concurrent analysis of its associated disease manifestations. Methods: Laboratory surveillance data on influenza, relevant population demographics, and …

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DCAF1 interacts with PARD3 to promote hepatocellular carcinoma progression and metastasis by activating the Akt signaling pathway

Jinyao Zhang, Yuze Shi, Ke Ding, Weiwei Yu et autres

BACKGROUND: Hepatocellular carcinoma (HCC) is a fatal malignancy with poor prognosis due to lack of effective clinical interference. DCAF1 plays a vital role in regulating cell growth and proliferation, and is involved in the progression of various malignancies. However, the function of …

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Involvement of reactive oxygen species in zinc-deficiency induced inhibition of crown root growth in maize plant

Jinyao Zhang, Yuwei Zhang, Shuhui Song, Yinghong Pan et autres

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Association of Blood Selenium Levels with Diabetes and Heart Failure in American General Adults: a Cross-sectional Study of NHANES 2011–2020 pre

Chongyang Zhang, Qingjia Zeng, Xinyao Liu, Qile He et autres

Selenium is an essential trace element closely related to human health; however, the relationship between blood selenium levels, diabetes, and heart failure remains inconclusive. Therefore, this study aimed to explore the relationship between blood selenium levels and the prevalence of diabetes as …

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Effectiveness of Haptic Modality in an Intelligent Bicycle Safety Driving Device Supporting Bicycle Delivery Service

Rui Li, Yu Zhang, Jinyao Zhang, Weizhuan Hu et autres

Deliverymen have widely adopted smart phone apps for better delivery performance. With the development of the delivery industry and the increase of its employees, the personal safety of deliverymen in completing orders has attracted the same attention as task performance. In addition …

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A TNFα/Miz1-positive feedback loop inhibits mitophagy in hepatocytes and propagates non-alcoholic steatohepatitis

Kangpeng Jin, Yuze Shi, Haitian Zhang, Guangyan Zhangyuan et autres

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