Iris Müller

P08-18: Development and validation of Mother-foetus PBK model: A case study of PBK read-across for Valproic acid and 2-Ethyl Hexanoic Acid

G Pawar, H. Li, Matthew Dent, Iris Müller et autres

gb (code pays fourni par la source)

Thrombus architecture is influenced by the antiplatelet loading treatment in patients with acute myocardial infarction

Tobias Harm, Dominik Rath, Klaus‐Peter Kreißelmeier, Livia Baas et autres

de (code pays fourni par la source)

[A toddler with a lump on his penis].

Iris Müller, Wim Opstelten

A father consulted his general practitioner with his 3-years-old son who had swelling on his penis for several months. He experienced no miction problems. The swelling appeared to be a retention of smegma. This is harmless and will disappear spontaneously as the …

nl, fr (code pays fourni par la source)

Cocaine and COVID-19 in ST-Elevation Myocardial Infarction

Florian Appenzeller, Meinrad Gawaz, Iris Müller

Both COVID-19 disease and cocaine consumption have prothrombotic and hypercoagulable effects and are associated with increased risk of cardiovascular events. We report the case of a patient with acute myocardial infarction in the setting of active COVID-19 disease and recent cocaine consumption. …

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Protective role of Gremlin‐1 in myocardial function

Iris Müller, Martina Schneider, Karin Müller, Oleg Lunov et autres

Abstract Background Gremlin‐1 is a cystine knot protein and is expressed in organs developing fibrosis. Transient ischaemia leads to myocardial fibrosis, a major determinant of impaired myocardial function. Materials and methods Expression of Gremlin‐1 was investigated in infarcted myocardium by real‐time PCR, …

de (code pays fourni par la source)

Regulation of oxidized platelet lipidome: implications for coronary artery disease

Madhumita Chatterjee, Dominik Rath, Jörg Schlotterbeck, Johannes Rheinlaender et autres

AIMS: Hyperlipidaemia enhances susceptibility to thrombosis, while platelet oxidixed LDL (oxLDL) binding in acute coronary syndrome (ACS) correlates with activation status. This study explores the platelet lipidome in symptomatic coronary artery disease (CAD) patients and the functional consequences of the chemokine CXCL12 …

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Platelets as a novel source of Gremlin-1: Implications for thromboinflammation

Madhumita Chatterjee, Alexander Behrendt, Martina Schmid, Sandra Beck et autres

Platelets mediating haemostasis-thrombosis are central players in coronary artery disease (CAD). We characterised platelets as a novel source of Gremlin-1. Platelets express Gremlin-1 like inflammatory and endothelial cells. Gremlin-1 co-localised with P-selectin containing randomly distributed α-granules under resting state, which were peripheralised …

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Case report. Een paraganglioom in de blaas

Iris Müller, Bernard A. Zonnenberg, Trudy Jonges, Tycho Lock

Wij beschrijven een casus van een 48-jarige vrouw met een atypische blaastumor. Patiënt is bekend met familiaire paragangliomen. Een catecholamineproducerende blaastumor zou tijdens een operatie een plotselinge bloeddrukstijging kunnen veroorzaken als gevolg van een catecholaminecrisis. Uit voorzorg werden daarom, voorafgaand aan de …

nl (code pays fourni par la source)

Cardiac Myeloid Sarcoma: Multimodality Radiologic Imaging Features and Pathologic Correlation

Daniela Dörfel, Maik Häntschel, Birgit Federmann, Susanne Haen et autres

de (code pays fourni par la source)

Advantages and Limitations of Direct PCR Amplification of Bacterial 16S-rDNA from Resected Heart Tissue or Swabs Followed by Direct Sequencing for Diagnosing Infective Endocarditis: A Retrospective Analysis in the Routine Clinical Setting

Daniela Maneg, Janina Sponsel, Iris Müller, Benedikt Lohr et autres

Infective endocarditis (IE) is a life-threatening disease that is associated with high morbidity and mortality. Its long-term prognosis strongly depends on a timely and optimized antibiotic treatment. Therefore, identification of the causative pathogen is crucial and currently based on blood cultures followed …

us, nl, de (code pays fourni par la source)

Insertable cardiac monitors after cryptogenic stroke – a risk factor based approach to enhance the detection rate for paroxysmal atrial fibrillation

Sven Poli, Jennifer Diedler, Nina Götz, Axel Bauer et autres

BACKGROUND AND PURPOSE: Recently, the CRYSTAL AF trial detected paroxysmal atrial fibrillation (AF) in 12.4% of patients after cryptogenic ischaemic stroke (IS) or cryptogenic transient ischaemic attack (TIA) by an insertable cardiac monitor (ICM) within 1 year of monitoring. Our aim was …

de (code pays fourni par la source)

Efficacy and safety of zero-fluoroscopy ablation for supraventricular tachycardias

Peter Seizer, V. Bucher, C. Frische, David Heinzmann et autres

de (code pays fourni par la source)