Jun Chen

Sb-Induced Coherent Twin-Phase Engineering for Structural Pinning and High-Voltage Stabilization of Ni-Rich Layered Cathodes

Tian Jiang, Jun Chen, Ying Lei, Zhilin Tao et autres

Abstract Ni-rich layered oxide cathodes received considerable research interest due to their high energy density, yet their cycling stability was severely limited by irreversible H2–H3 phase transition-induced lattice strain accumulation and lattice oxygen release, especially at high voltage. Here, we report a …

cn (code pays fourni par la source)

Decoding Immune Reconstitution Failure in People Living with HIV through Single-cell Genomics

Yuxing Wang, Shichen Yang, Yue Yuan, Mingli Zhu et autres

Abstract Immune non-responders (INRs), a subset of people living with HIV (PLWH), fail to achieve full immune reconstitution and remain at increased risk of morbidity, mortality, and non-AIDS-related illnesses. As the mechanisms underlying this impaired immune recovery remain poorly understood, we performed …

cn, hk (code pays fourni par la source)

Machine Learning-Based Identification of Molecular Signatures in PTOA Cell Subtypes via Single-Cell Transcriptomics in a Mouse Model

Dun Yang, Gaowen Gong, Jun Chen, Jiafeng Song et autres

cn (code pays fourni par la source)

Abstract 6866: Mapping cancer-relevant genetic interactions with functional module prediction and in4mer enCas12a platform.

Chenchu Lin, Veronica Gheorghe, Juihsuan Rosalind Chou, Sabriyeh Alibai et autres

Abstract Genetic interaction (GI), particularly synthetic lethality, is essential to functional genomics and cancer therapy. In yeast, systematic GI mapping has produced a near-complete network covering ∼90% of genes, establishing core principles of GI network architecture and defining major functional modules. However, …

us (code pays fourni par la source)

Abstract 6894: Predict, perturb, and process: A systems biology pipeline for identifying synthetic lethality.

Juihsuan Chou, Chenchu Lin, Iulia Veronica Gheorghe, Sabriyeh Alibai et autres

Abstract The synthetic lethality principle holds great promise for cancer therapy, but identifying synthetic lethals presents enormous challenges. Synthetic lethality, where loss of two genes causes cell death, but loss of either gene alone does not, is difficult to assay because combinatorial …

us (code pays fourni par la source)

A single-cell multi-omics atlas of human eyelid skin

Weiguang Ma, Yanwen Xu, Jun Chen, Yuan Yu et autres

The skin acts as the first barrier protecting the human body against the external environment. Transcriptional heterogeneity in human skin is widely confirmed, but the regulatory mechanisms remain largely unexplored. In this study, we employed high-throughput single-cell chromatin accessibility and transcriptome sequencing …

Botswana, au, cn (code pays fourni par la source)

Mechanisms of Electrochemical Degradation of Low-Concentration Azo Dye Wastewater by a Typical Binary Anion System

Ming Chen, Kewen Li, H. W. Deng, Chuanhan Chen et autres

The secondary effluent from printing and dyeing wastewater contains recalcitrant organic pollutants, such as azo dye derivatives. Their persistence in aquatic environments not only creates ecological risks but also hampers the high-value reuse of reclaimed water. This study investigated the influence of …

cn (code pays fourni par la source)

Synergistic bandgap regulation and conductive network engineering for high-rate and long-life Na3V2(PO4)3 cathodes

Zhilin Tao, Tian Jiang, Jinlong Chen, Jinlong Chen et autres

cn (code pays fourni par la source)

Investigation of the effect of zeolite topology on the diffusion and release behavior of encapsulated antibacterial silver nanoparticles

Shaofeng Gong, Mengxi Han, Yichun Cai, Chengen Ho et autres

cn (code pays fourni par la source)

FACS-based genome-wide CRISPR screening platform identifies modulators of CD47

Ling Yin, Wei He, Yifan Wang, Huimin Zhang et autres

Background: CD47 is a key innate immune checkpoint that enables tumor cells to evade macrophage-mediated clearance. Methods/Results: To systematically identify genetic regulators of CD47 surface expression, we performed FACS-based genome-wide CRISPR screens in three murine cancer cell lines B16 (melanoma), MC38 (colon …

us (code pays fourni par la source)

Mechanistic insights into sulfamethoxazole removal in activated sludge systems through machine learning and microcosm experiments

Jun Chen, Lipin Li, Xiaowei Lv, Tao Liu et autres

cn, be (code pays fourni par la source)

MassIVE MSV000100499 - To profiling the protein and phosphorylation under CDK5 knockout

Jun Chen

us (code pays fourni par la source)