Chao Jiang

Brominated monomer-enabled polyester tight ultrafiltration membranes for efficient dye/salt separation and anti-fouling performance

Jiulong Yin, Qi Lei, Na Li, Meng Li et autres

Sarcopenia and Long-Term Outcome in Adults and Children Undergoing Split Liver Transplantation

Xin Yuan Sui, Chao Jiang, Jiaxin Liu

Purpose: Primary hyperoxaluria type 1 (PH1), a rare autosomal recessive disorder associated with hepatic oxalate overproduction, leads to kidney failure, with poor historical graft survival rates after isolated kidney transplantation (iKT). A Phase 2 (NCT03350451) and 3 Phase 3 trials (ILLUMINATE-A, NCT03681184; …

Real-world treatment patterns in stage III ALK+ NSCLC patients in China: A multicenter retrospective study.

Linlin Wang, Xiao Hu, Baoxing Liu, Jianzhong Cao et autres

e20077 Background: Stage III non-small cell lung cancer (NSCLC) is highly heterogeneous and ALK+ patients (pts) lack of standard treatment model. Thus, there is a huge unmet need to understand real-world treatment patterns, and relationship to survival outcomes in stage III ALK+ …

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A Robust ROS Generation and Ferroptotic Lipid Modulation Nanosystem for Mutual Reinforcement of Ferroptosis and Cancer Immunotherapy

Chao Jiang, Wenxi Li, Jie Yan, Xinying Yu et autres

Abstract Ferroptosis initiation is often utilized for synergistic immunotherapy. While, current immunotherapy is limited by an immunosuppressive tumor microenvironment (TME), and ferroptosis is limited by insufficient reactive oxygen species (ROS) and ferroptotic lipids in tumor cells. Here, an arachidonic acid (AA) loaded …

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Bulky Primary Thoracic Sarcomas in Children Treated with Preoperative Proton Radiotherapy

Chao Jiang, Casey Mogilevsky, G. Kurtz, Theodore Willis Laetsch et autres

Three-way junction structure-mediated reverse transcription-free exponential amplification reaction for pathogen RNA detection

Xinguang Zhang, Yang Li, Qing Kenneth Wang, Chao Jiang et autres

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Elimination of Unspecific Amplification in the Exponential Amplification Reaction Using Polyethylene Glycol 200 (PEG 200) as a Cosolute

Chao Jiang, Yang Li, Xinguang Zhang, Yuting Shan et autres

Exponential amplification reaction (EXPAR) enables extremely rapid nucleic acid measurements. However, the nonspecific amplification in EXPAR limits its application, especially for low abundance target nucleic acids. Herein, polyethylene glycol 200 (PEG200), a widely available small-molecular cosolute, is described to suppress this nonspecific …

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Efficacy and safety of PD-1/PD-L1 inhibitor plus platinum-based chemotherapy vs. platinum-based chemotherapy alone in patients with previously untreated advanced large-cell neuroendocrine cancer of the lung.

Fengchun Mu, Bingjie Fan, Haoqian Li, Taotao Dong et autres

9066 Background: Large-cell neuroendocrine carcinoma (LCNEC) is a rare tumor with a poor prognosis and limited treatment options. The efficacy of first-line therapies for LCNEC has not yet been established. This study evaluated the efficacy and safety of the combination of PD-1/PD-L1 …

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Conversion therapy in liver transplantation for hepatocellular carcinoma: What's new in the era of molecular and immune therapy?

Chao Jiang, Xiaodong Sun, Wei Qiu, Yuguo Chen et autres

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The Prognostic Value of TP53 Alteration in Patients with Head and Neck Squamous Cell Carcinoma Receiving Immunotherapy

Chao Jiang, Xuanchen Zhou, Jie Han, Zhiyong Yue et autres

The article by Wilson et al., published in the February 2021 issue, reported the prognostic value of circulating tumor DNA (ctDNA) sequencing in head and neck squamous cell carcinoma (HNSCC), noting TP53 as the most altered and concordant gene in ctDNA and …

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Comprehensive Analysis on Prognosis and Immune Infiltration of Lysyl Oxidase Family Members in Pancreatic Adenocarcinoma With Experimental Verification

Chao Jiang, Meng Wang, Weikai Yao, Guoyue Lv et autres

Background: Pancreatic adenocarcinoma (PDAC) is the most aggressive among all solid malignancies with delayed disease detection and limited effective treatment. However, due to the intricate heterogeneity and exclusive tumor microenvironment (TME), the development of effective therapy has been facing enormous challenges. The …

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The nonlinear association between albumin levels and risk of noninvasive fungal rhinosinusitis

Chao Jiang, Xiaoyue Zhen, Xin Zhang, Ling Guo et autres

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