Xiaohua Wang

miR-889-3p targets SLC35E1 in leprosy: Implications for therapeutic monitoring

Yang Li, Lei Chen, Zepu Guan, Liting Cai et autres

BACKGROUND: Leprosy is a chronic infectious disease caused by Mycobacterium leprae (M. leprae). Despite significant progress in disease control, the molecular mechanisms regulating host responses to M. leprae infection remain incompletely understood. MicroRNAs (miRNAs) are important post-transcriptional regulators that modulate immune responses …

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Association between interoceptive sensitivity and impaired fasting glucose in early pregnancy: the mediating effect of dietary quality distance and food variety

Xiaohan Tan, Qianqian Tian, Bin Liu, Wei Zhang et autres

Abstract Background Early pregnant women often experience changes in their dietary patterns. Interoceptive sensitivity (IS), the ability to detect internal bodily signals, influences appetite regulation and dietary choices, potentially impacting glucose metabolism. Whether IS is a protective factor against elevated FBG in …

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Immediate health and wellbeing benefits of short-term forest therapy for urban healthcare workers: a case study in Giant Panda National Park with cultural ecosystem services

Ping Zhang, Yixin Cui, Rui Liu, Yifei Zhao et autres

The increasing frequency and prominence of global public health threats put urban healthcare workers at risk of physical and mental illness. Forest therapy holds crucial importance in promoting human health as a non-material benefit obtained from ecosystems. Cultural ecosystem services (CES) profoundly …

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Current status and influencing factors of digital competence among nurses in intensive care units: a cross-sectional study

ZY Wei, Congcong Liu, Jicheng Zhang, Chunmei Fan et autres

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Editorial: Subjective sensations in obesity and related chronic diseases

Xiaohua Wang, Omorogieva Ojo

high prevalence of overweight and obesity and the consequent health risks, it has become a major global public health problem. At present, obesity is recognized as one of the important risk factors for chronic diseases such as type 2 diabetes mellitus, cardiovascular …

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Prevalence and influencing factors of obesity in preschool children in Suzhou, China

Yu Zhang, Xu Zhang, Xiaohua Wang, Zhen Wu et autres

BACKGROUND: The study aims to assess the prevalence of obesity among preschool children in Suzhou, China, and analyze potential risk factors to the condition. METHODS: The study included preschool children aged 3-6 from various kindergartens in Suzhou. Height and weight measurements were …

Translation and psychometric evaluation of the Chinese version of the Digital Competence Questionnaire for clinical nurses

ZY Wei, Hongli Liu, Jicheng Zhang, Yan Chen et autres

Background: Adequate digital competence is crucial for clinical nurses to effectively adapt to the evolving digital technologies in their practice. Currently, there is a lack of a brief assessment tool in China that comprehensively measures the digital competence of nurses in clinical …

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The Role and Implications of Epidermal Dysfunction in the Pathogenesis of Inflammaging

Jiechen Zhang, Bijun Xia, Xiaohua Wang

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Examining the audiovisual therapy effects on hospital groups of varying linear canopy landscapes and those with hydrodynamic forces

Ping Zhang, Yixin Cui, Ke Luo, Tongyao Zhang et autres

Recent research has highlighted the beneficial effects of urban green spaces on physical and mental health. This study focused on the hospital population and innovatively subdivided the population into four groups: doctors, caregivers, patients and nurses. A total of 96 volunteers participated …

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Construction of an Early Risk Prediction Model for Type 2 Diabetic Peripheral Neuropathy Based on Random Forest

Zhengang Wei, Xiaohua Wang, Liqin Lu, Li Su et autres

Diabetic peripheral neuropathy is a major cause of disability and death in the later stages of diabetes. A retrospective chart review was performed using a hospital-based electronic medical record database to identify 1020 patients who met the criteria. The objective of this …

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Two cases of eosinophilic pustular folliculitis successfully treated with abrocitinib

Liting Cai, Yunling Yan, Li Yang, Junjie Lin et autres

Eosinophilic pustular folliculitis (EPF) is a rare, non-infectious, inflammatory disease characterized by an eosinophil-dominated infiltrate within and around pilosebaceous units. Sometimes, EPF manifests with eruptions in follicle-free areas, although it is not common, and treatment may be difficult. In this case study …

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SLC35E1 promotes keratinocyte proliferation in psoriasis by regulating zinc homeostasis

Tao Huang, Shijun Chen, Ke Ding, Baoqing Zheng et autres

Abstract Keratinocyte hyperproliferation is a key pathogenic factor in psoriasis. However, the mechanisms that regulate keratinocyte hyperproliferation in this condition remain unclear. Here, we found that SLC35E1 was highly expressed in keratinocytes of patients with psoriasis and that Slc35e1−/− mice displayed a …

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