Lirong Zhang

Brain region-specific lesions in the early AIDS monkey model

Tian‐Zhang Song, Yan Hu, Shi-Zhe Wang, Huan-Zhi Chen et autres

Abstract Brain lesions show pronounced regional heterogeneity during chronic or advanced human immunodeficiency virus (HIV) infection, however, the regional neuropathogenesis during the acute phase remains unclear. By establishing an acute simian immunodeficiency virus (SIV)-infected model in rhesus macaques, we found acute infection …

cn, hk (code pays fourni par la source)

Morphological and molecular data reveal Cerrena caulinicystidiata sp. nov. and Polyporus minutissimus sp. nov. in Polyporales from Asia

Zi-Wei Zheng, Qiu-Yue Zhang, Lirong Zhang, Hai‐Sheng Yuan et autres

This dataset contains the digitized treatments in Plazi based on the original journal article Zheng, Zi-Wei, Zhang, Qiu-Yue, Zhang, Li-Rong, Yuan, Hai-Sheng, Wu, Fang (2024): Morphological and molecular data reveal Cerrena caulinicystidiata sp. nov. and Polyporus minutissimus sp. nov. in Polyporales from …

cn (code pays fourni par la source)

Spatial transcriptomics in cancer research: insights into tumorigenesis, diagnosis and therapeutics

Qiang Wen, Qing Lan, Jianjian Yin, Fei Guo et autres

Spatial transcriptomics is an innovative technology that enables high-throughput, genome-wide analysis of transcript expression and spatial localization within tissues. By preserving structural organization, it provides critical insights into tumor sub-regions, substructures, and the heterogeneity and plasticity of cancer, stromal, and immune cells, …

cn, au (code pays fourni par la source)

RNA Sequencing and Targeted Knockdown Reveal miR-142a-5p as a Driver of Retinal Degeneration in rd1 Mice

Na Yang, Meng Liang Zhao, Nan Guo, Mei Yang et autres

Retinitis pigmentosa (RP), an inherited retinal disorder, leads to progressive photoreceptor degeneration and irreversible blindness, with limited treatment options available. Emerging evidence implicates microRNAs (miRNAs) in the pathogenesis of retinal disease, yet understanding of their specific roles in RP remains incomplete. In …

cn (code pays fourni par la source)

HNF4A-AS1 promotes hepatic steatosis in metabolic dysfunction–associated steatotic liver disease by driving HNF4A degradation

Mengyao Yan, Xiaofei Wang, Xiaoyang Hou, Zijing Wang et autres

cn (code pays fourni par la source)

Regulation of Melatonin on AQP4 Expression in Brain of SD Newborn Rats with Bilirubin Encephalopathy and Protection Mechanism

Xuefeng Cheng, Weijian Qian, Hemant Mistry, Ping Fan et autres

th, cn, gb (code pays fourni par la source)

Enhanced Nutritional Support May Ameliorate Rivaroxaban-Related Rapid Renal Function Decline: New Insights from a Real-World Study

Meng Cheng, Linjie Li, Ying Han, Xinxin Zhang et autres

Aim: Aim to compare the effects of rivaroxaban and warfarin on rapid renal function decline. Methods: 8842 patients from the Tianjin Health and Medical Data Platform, with a 2.3 years median follow-up (interquartile range,1.5– 3.4), were assigned to either the warfarin group …

cn (code pays fourni par la source)

MSR47 BHM and BHM-Based Extrapolations in an HTA Framework

Katrin Haeussler, K. Dunton, Lirong Zhang, Georgie Weston et autres

de, gb, us (code pays fourni par la source)

Serum Proteomics Reveals Diagnostic Biomarkers and Molecular Pathways in Cerebral Palsy

Yiran Xu, Chi Ma, Yanyan Sun, Jiajun Zhu et autres

Cerebral palsy (CP), a prevalent non-progressive neurological disorder in children, lacks reliable biomarkers for early diagnosis, and its molecular mechanisms remain poorly understood. In this study, we conducted serum proteomic profiling of 346 CP patients and 190 healthy controls and developed a …

cn, us, se, au (code pays fourni par la source)

Real-World Characteristics, Treatment Patterns, and Outcomes in Advanced HER2 (ERBB2)-Mutant Non-Small Cell Lung Cancer: A Retrospective Study of Single Centers in France and Germany

Petros Christopoulos, Christin Assmann, Lirong Zhang, K. Dunton et autres

PURPOSE: Human epidermal growth factor receptor 2 (HER2 [ERBB2]) gene mutations occur in ∼3-5% of non-small cell lung cancer (NSCLC) cases and are associated with poor prognosis. However, real-world data on patients with HER2-mutant (HER2m) NSCLC are needed. METHODS: This retrospective, observational …

de, gb, kr, fr, pl, us (code pays fourni par la source)

Lactylation in Cardiovascular Diseases: Current Progress and Perspectives

Zhi‐Mo Wang, Qingwen Yu, Cong Wang, Shuhui Wang et autres

Emerging evidence suggests that epigenetic modifications, including lactylation-a recently identified posttranslational modification-may play a role in cardiovascular diseases (CVDs). Lactylation occurs in both histone and nonhistone proteins and has been implicated in processes, such as inflammation, lipid metabolism, and angiogenesis, which are …

cn (code pays fourni par la source)

Strong interaction between high-entropy alloy catalysts and solvent molecules facilitating the polysulfide conversion in lean-electrolyte lithium-sulfur batteries

Fengfeng Han, Lirong Zhang, Qi Jin, Zhiguo Zhang et autres

cn (code pays fourni par la source)