Jingyuan Zhao

Application of photodynamic activation of prodrugs combined with phototherapy in tumor treatment

Yining Du, Jingyuan Zhao, Shuai Li, Hong Yuan

The design of prodrugs aims to address the issues of systemic toxicity and poor specificity associated with traditional chemotherapy drugs, thereby improving patient survival rates. However, effectively controlling the activation of prodrugs and further improve the efficacy remains a significant challenge that …

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Sustainable Urban Development: A Comprehensive Model for Assessing Health Risks from Compounded Pollution in Xi’an

Lichen Liu, Jingyuan Zhao, Zhaoxin Li

Global climate change and rapid urbanization have brought unprecedented environmental challenges, especially in rapidly expanding cities like Xi’an, posing potential challenges to sustainable development if not accompanied by adequate greenery, thoughtful layouts, and pollution control measures. The increasing frequency and intensity of …

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Elevated plasma matrix metalloproteinase 9 in schizophrenia patients associated with poor antipsychotic treatment response and white matter density deficits

Xiaojing Li, Xiujuan Wang, Yongfeng Yang, Jiahui Zhou et autres

Oxidative stress and neuroinflammation contribute to schizophrenia (SCZ) pathology and may influence treatment efficacy. Matrix metalloproteinase 9 (MMP9) is a critical molecular node mediating the interaction between oxidative stress and inflammation, and so may influence treatment efficacy. Here we examined the associations …

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RUNX1 regulates MCM2/CDC20 to promote COAD progression modified by deubiquitination of USP31

Wei Tian, Jingyuan Zhao, Xinyu Zhang, Pengfei Li et autres

Colon adenocarcinoma (COAD) is the second leading cause of cancer death, and there is still a lack of diagnostic biomarkers and therapeutic targets. In this study, bioinformatics analysis of the TCGA database was used to obtain RUNX1, a gene with prognostic value …

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Numerical simulation study on impact factors to dynamic filtration loss

Cuilong Kong, Yuxue Sun, LI Cheng-li, Jingyuan Zhao et autres

Abstract During drilling operations, naturally, fractured formations are prone to show serious mud losses, which hinder drilling and increase nonproductive time and costs. The influencing factors of dynamic fluid loss are important for optimizing drilling parameters, reducing drilling fluid loss, and protecting …

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Experimental Simulation of Proppant Migration for Slick Water With Variable Viscosity During Fracturing

Guiquan Wang, Jingyuan Zhao, Yuxue Sun, Anqi Shen

The migration law of proppants in slick water during fracturing is of great significance for field fracturing. A large‐scale visualized experimental device was utilized to test sand patterns for varying injection parameter combinations, and sensitivity parameters of proppant settlement are analyzed. Experimental …

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Thermal comfort and adaptive behaviors in office buildings: A pilot study in Turpan (China) during summer

Yuang Guo, Hao Tang, Yali Gao, Yuxin Wang et autres

Nowadays, evaporatively cooled office buildings commonly observed in dry hot areas in summer of China. However, few dedicated studies to record the local residents' thermal comfort and adaptability in these buildings. The contribution of adaptive comfort theory on thermal perception still remains …

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Thermal Comfort and Adaptive Behaviors in Office Buildings: A Pilot Study in Turpan (China) During Summer

Yuang Guo, Hao Tang, Yali Gao, Yuxin Wang et autres

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Energy-saving optimization based on residential building orientation and shape with multifactor coupling in the Tibetan areas of western Sichuan, China

Wenjing Ren, Jingyuan Zhao, Ming Chang

Following field-based research and testing of residential buildings in Tibetan areas of western Sichuan, this study studied the interactions between and dynamic effects of geographic and meteorological elements. By quantifying the combined influence of geographical and meteorological elements on building orientation, the …

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Indoor Thermal Comfort of the Expressway Service Area in Qinling Mountains

Bo Xia, Shijing Zhao, Fei Han, Xinyu Zhang et autres

Improving indoor thermal environment in a traditional building of Danihe Village, China with additional solar house

Lei Zhang, Xuan Ma, Jingyuan Zhao, Jianxin Zhang et autres

A considerable chunk of population in China live in rural areas. To create a suitable living environment in winter, many of them resort to additional solar house to improve the indoor thermal environment. Most of the previous studies focus on how the …

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Building Thermal Comfort Research Based on Energy‐Saving Concept

Feiran Xue, Jingyuan Zhao

Under the trend of building green and comfortable development, effective control of building energy consumption has become one of the problems that countries are actively facing to solve. People’s demand for residential buildings has changed from the past survival type to a …

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