Yang Gao

Integrating Network Pharmacology and Experimental Verification to Explore the Targets for Colchicine against Coronary In-Stent Restenosis

Yang Gao, Qingbo Shi, Zhuocheng Shi, Zhiwen Zhang et autres

INTRODUCTION: In-Stent Restenosis (ISR) remains a challenging complication following vascular interventions. Colchicine, a well-known anti-inflammatory agent, has shown potential in reducing ISR, but its multi-target mechanisms remain unclear. This study aims to elucidate the pharmacological mechanisms of colchicine against ISR using an …

cn (code pays fourni par la source)

Neutrophil extracellular trap-related signature predicts the prognosis and immunotherapy outcome of lung adenocarcinoma

Yuquan Bai, Yang Gao, Xu He, Fan Gao et autres

Neutrophil extracellular traps (NETs) are a kind of DNA reticular structure that can capture and kill pathogenic microorganisms. NETs are closely related to the progression of tumors, but the role of NETs in the immunotherapy of lung adenocarcinoma (LUAD) remains unclear. We …

cn (code pays fourni par la source)

Osimertinib resistance-based immune prognostic related gene signature in EGFR mutant lung adenocarcinoma, in which PSMD11 promotes tumor progression

Yuquan Bai, Xu He, Peilong Bao, Yang Gao et autres

Background: At present, epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) treatment, as the first-line treatment of lung adenocarcinoma (LUAD) with EGFR mutation, has achieved good clinical efficacy, but most patients will eventually develop acquired resistance. The objective of this study is …

cn (code pays fourni par la source)

Role of lifestyle factors in mediating the effect of mood swings on cardiovascular diseases: A mediation Mendelian randomization study

Zhiyong Shi, Yang Gao, Qingbo Shi, Zhiwen Zhang et autres

It has been found that individuals with psychiatric illnesses are predisposed to an elevated risk of cardiovascular diseases (CVDs). Mood swing is a clinically relevant characteristic linked to psychiatric disorders. This study examined the possible relationship between genetically predicted mood swings and …

cn (code pays fourni par la source)

Continuous renal replacement therapy in combination with oXiris haemofilter in a paediatric patient with sodium valproate-induced acute pancreatitis

Ying Wang, Yang Gao, Kai Kang

Some clinical trials have validated a new perspective on continuous renal replacement therapy (CRRT) in combination with oXiris haemofilter to more effectively enhance endotoxins clearance and circulating cytokines adsorption, stabilise vital signs, correct haemodynamic disorders and accelerate the recovery of organ function, …

cn (code pays fourni par la source)

Lymphocyte-C-reactive protein ratio upon admission to predict disease progression and ICU admission in adult patients with diabetic ketoacidosis

Yongsheng Hu, Shu-Xiao Qiu, Jian-Nan Zhang, Qi-Qi Lai et autres

This study aimed to investigate whether lymphocyte-C-reactive protein ratio (LCR) upon admission can predict disease progression and intensive care unit (ICU) admission in adult patients with diabetic ketoacidosis (DKA). A single-center retrospective study was conducted, including adult DKA patients admitted to the …

cn (code pays fourni par la source)

Terahertz spectroscopy study of oridonin and ponicidin in the anticancer Chinese herbal medicine Rabdosia rubescens

Yang Gao, Peng Zhuang, Huiyu Yang, Xinrui Zhang et autres

Rabdosia rubescens, a Chinese herbal medicine with anticancer properties, contains two active ingredients: oridonin and ponicidin. Both compounds exhibit antitumor effects by inducing tumor cell apoptosis and autophagy and inhibiting tumor cell proliferation. To further explore the differences in molecular structure and …

cn (code pays fourni par la source)

[Medicinal Characteristics of Shao Jiu in Compendium of Materia Medica].

Z H Liu, Yang Gao, Dayang Shi, Luchang Cao et autres

can also provide a reference for the medicinal use of modern liquor.

cn (code pays fourni par la source)

Nocturnal oxygen saturation is associated with all-cause mortality: a community-based study

Bin Yan, Yang Gao, Zhanqin Zhang, Tao Shi et autres

cn (code pays fourni par la source)

Vitro UPLC analysis and mass method identification, and in vivo or cellular immune anti-inflammatory function of Sanhuang Xiexin Decoction (SHXD)

Yang Gao, Shi-Qiao Liu, Jialong Wang, Hanming Cui et autres

cn (code pays fourni par la source)

Effects of Ving Tsun sticking-hand training on lower limb sensorimotor performance among community-dwelling middle-aged and older adults: a randomized controlled trial

Shirley S.M. Fong, Louisa Ming Yan Chung, Timothy T.T. Yam, Joanne W. Y. Chung et autres

BACKGROUND: To explore the effects of Ving Tsun (VT) sticking-hand training on knee joint proprioception and leg muscular performance among community-dwelling middle-aged and older adults. METHODS: Thirty-three middle-aged and older adults were randomly assigned to either the VT or control group. The …

cn, hk, kr, tw (code pays fourni par la source)

Studying the imaging features and infarction mechanism of vertebrobasilar dolichoectasia with high‐resolution magnetic resonance imaging

Tao Zheng, Wenxiong Tang, Yi Shan, Runcai Guo et autres

The mechanisms underlying ischemic infarction in patients with vertebrobasilar dolichoectasia (VBD) remain unclear. In this study, we retrospectively analyzed the imaging characteristics of high-resolution magnetic resonance imaging (HR-MRI) in patients with VBD to explore the possible mechanisms of ischemic stroke (IS) in …

cn (code pays fourni par la source)