Liang Chang

Healthy aging among community-dwelling older adults aged ≥60 years in China: results from a 2023 cross-sectional study

Hui Li, Li Gao, Yan Gao, H. Zhang et autres

Background and aims With the global population aging, this study aimed to estimate the prevalence of healthy aging and its associated factors in China. Methods This cross-sectional study was conducted in Henan Province, China, in 2023. A multi-stage, stratified, probability-proportional-to-size (PPS) sampling …

cn, tw (code pays fourni par la source)

Associations of Healthy Sleep Patterns with Psoriasis Risk: Insights from a Longitudinal Cohort Study

Jie Zhang, Zixing Zhang, Liang Chang, Dong‐Qing Ye et autres

cn (code pays fourni par la source)

Fetal exposure to famine increases the risk of cardiovascular disease in adulthood: findings from a population-based screening study

Minjie Qi, Shuxian Yang, H. Zhang, Liang Chang et autres

Introduction: Undernutrition during early life may increase the risk of chronic diseases in adulthood. The study aimed to investigate whether fetal exposure to famine would increase the risk of cardiovascular disease (CVD) in adulthood. Materials and methods: Data were collected from 16 …

cn (code pays fourni par la source)

Impact of Social Isolation on Inflammatory Bowel Disease Risk and the Mitigating Effect of a Healthy Lifestyle

Liang Chang, Jie Zhang, Mengmeng Xu, Miaomiao Zhang et autres

cn (code pays fourni par la source)

Association between health insurance cost-sharing and choice of hospital tier for cardiovascular diseases in China: a prospective cohort study

Muriel Levy, John Buckell, Robert Clarke, Nina Wu et autres

Background: Hospitals in China are classified into tiers (1, 2 or 3), with the largest (tier 3) having more equipment and specialist staff. Differential health insurance cost-sharing by hospital tier (lower deductibles and higher reimbursement rates in lower tiers) was introduced to …

gb, cn, us (code pays fourni par la source)

Author response for "The gut microbiome modulates the susceptibility to traumatic stress in a sex‐dependent manner"

Dan Shen, Liang Chang, Feng Su, Shihao Huang et autres

PCSK9 genetic variants and risk of vascular and non-vascular diseases in Chinese and UK populations

Michael V. Holmes, Christiana Kartsonaki, Ruth Boxall, Kuang Lin et autres

AIMS: Lowering low-density lipoprotein cholesterol (LDL-C) through PCSK9 inhibition represents a new therapeutic approach to preventing and treating cardiovascular disease (CVD). Phenome-wide analyses of PCSK9 genetic variants in large biobanks can help to identify unexpected effects of PCSK9 inhibition. METHODS AND RESULTS: …

gb, cn (code pays fourni par la source)

Author response for "The gut microbiome modulates the susceptibility to traumatic stress in a sex‐dependent manner"

Dan Shen, Liang Chang, Feng Su, Shihao Huang et autres

Plasma Proteomics to Identify Drug Targets for Ischemic Heart Disease

Mohsen Mazidi, Neil Wright, Pang Yao, Christiana Kartsonaki et autres

BACKGROUND: Integrated analyses of plasma proteomic and genetic markers in prospective studies can clarify the causal relevance of proteins and discover novel targets for ischemic heart disease (IHD) and other diseases. OBJECTIVES: The purpose of this study was to examine associations of …

gb, cn (code pays fourni par la source)

Sleep duration and risk of stroke and coronary heart disease: a 9-year community-based prospective study of 0.5 million Chinese adults

Yiping Chen, Christiana Kartsonaki, Huaidong Du, Canqing Yu et autres

BACKGROUND: There is uncertainty about the optimum sleep duration for risk of different subtypes of stroke and ischaemic heart disease. METHODS: The present analyses involved 409,156 adults in the China Kadoorie Biobank study without a prior history of coronary heart disease or …

gb, cn (code pays fourni par la source)

Alcohol consumption and risks of more than 200 diseases in Chinese men

Pek Kei Im, Neil Wright, Ling Yang, Ka Hung Chan et autres

Alcohol consumption accounts for ~3 million annual deaths worldwide, but uncertainty persists about its relationships with many diseases. We investigated the associations of alcohol consumption with 207 diseases in the 12-year China Kadoorie Biobank of >512,000 adults (41% men), including 168,050 genotyped …

gb, cn (code pays fourni par la source)

Healthy lifestyle, DNA methylation age acceleration, and incident risk of coronary heart disease

Jiahui Si, Lu Chen, Canqing Yu, Dianjianyi Sun et autres

BACKGROUND: DNA methylation clocks emerged as a tool to determine biological aging and have been related to mortality and age-related diseases. Little is known about the association of DNA methylation age (DNAm age) with coronary heart disease (CHD), especially in the Asian …

cn, gb, us (code pays fourni par la source)