Cong Hua Xie

MegaScale-MoE: Large-Scale Communication-Efficient Training of Mixture-of-Experts Models in Production

Chao Jin, Ziheng Jiang, Zhihao Bai, Zheng Zhong et autres

We present MegaScale-MoE, a production system tailored for the efficient training of large-scale mixture-of-experts (MoE) models. MoE emerges as a promising architecture to scale large language models (LLMs) to unprecedented sizes, thereby enhancing model performance. However, existing MoE training systems experience a …

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Association between endometriosis and adverse reproductive and perinatal outcomes in women undergoing assisted reproductive technology: a systematic review and meta-analysis

Yan Wei, Xiong Xiao, Xixi Wu, Cong Hua Xie et autres

Background With the increasing use of assisted reproductive technology (ART), more women with endometriosis are achieving pregnancy through ART. However, the impact of endometriosis on pregnancy and perinatal outcomes following ART remains controversial. This study aimed to clarify the association between endometriosis …

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A novel triazole derivative ameliorates ethanol-induced gastric ulcer via a NOS2-centered inhibition of the AGE-RAGE pathway

Cong Hua Xie, Jiahui Yue, WY He, Changbin Yu

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Cautious Weight Decay

Lizhang Chen, Jonathan Li, Kaizhao Liang, Bo Su et autres

We introduce Cautious Weight Decay (CWD), a one-line, optimizer-agnostic modification that applies weight decay only to parameter coordinates whose signs align with the optimizer update. Unlike standard decoupled decay, which implicitly optimizes a regularized or constrained objective, CWD preserves the original loss …

Toward precision medicine in COPD: phenotypes, endotypes, biomarkers, and treatable traits

Cong Hua Xie, Kepeng Wang, Kai Yang, Yuanyuan Zhong et autres

Abstract Chronic obstructive pulmonary disease (COPD) is a heterogeneous disorder characterized by diverse clinical manifestations, pathophysiological mechanisms, and therapeutic responses. This review explores the evolving landscape of precision medicine in COPD management, with particular emphasis on optimizing patient care through the integration …

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Metformin slows intestinal glucose absorption in type 2 diabetes, irrespective of the timing of its administration

Malcolm J. Borg, Cong Hua Xie, Chang Chen, Michelle J. Bound et autres

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The Influence of Rainfall Infiltration on Particle Migration of Coarse‐Grained Soil Filler

Qiyun Wang, Jian Kang, Cong Hua Xie, Shengyang Ou et autres

Abstract The intellectualization and informatization of railway subgrade monitoring is the current development trend. The change of physical and mechanical properties of the subgrade is the basis of intelligent identification. Therefore, it is necessary to reveal the influence of rainfall infiltration on …

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Effects of Metformin on Postprandial Blood Pressure, Heart Rate, Gastric Emptying, GLP-1, and Prevalence of Postprandial Hypotension in Type 2 Diabetes: A Double-Blind Placebo-Controlled Crossover Study

Daniel Robert Quast, Cong Hua Xie, Michelle J. Bound, Jacqueline Grivell et autres

Individuals with type 2 diabetes are at high risk of postprandial decrease in blood pressure (BP; i.e., a reduction in systolic BP of ≥20 mmHg, termed postprandial hypotension [PPH]), which increases the risk of falls and mortality. This study evaluated the effects …

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Effects of metformin on postprandial blood pressure, heart rate, gastric emptying, GLP-1 and the prevalence of postprandial hypotension in type 2 diabetes – a double-blind, placebo-controlled crossover study

Daniel Robert Quast, Cong Hua Xie, Michelle J. Bound, Jacqueline Grivell et autres

Individuals with type 2 diabetes are at high risk of postprandial falls in blood pressure (BP) (i.e., a reduction in systolic BP of ³20mmHg, termed postprandial hypotension (PPH)), which increases the risk of falls and mortality. This study evaluated the effects of …

de, au (code pays fourni par la source)

Effects of metformin on postprandial blood pressure, heart rate, gastric emptying, GLP-1 and the prevalence of postprandial hypotension in type 2 diabetes – a double-blind, placebo-controlled crossover study

Daniel Robert Quast, Cong Hua Xie, Michelle J. Bound, Jacqueline Grivell et autres

Individuals with type 2 diabetes are at high risk of postprandial falls in blood pressure (BP) (i.e., a reduction in systolic BP of ³20mmHg, termed postprandial hypotension (PPH)), which increases the risk of falls and mortality. This study evaluated the effects of …

Impact of the timing of metformin administration on the plasma lactate response to intraduodenal glucose infusion in type 2 diabetes

Cong Hua Xie, Peter E. Iroga, Michelle J. Bound, Jacqueline Grivell et autres

au (code pays fourni par la source)

MoE-Pruner: Pruning Mixture-of-Experts Large Language Model using the Hints from Its Router

Yanyue Xie, Zhi Zhang, Ding Zhou, Cong Hua Xie et autres

Mixture-of-Experts (MoE) architectures face challenges such as high memory consumption and redundancy in experts. Pruning MoE can reduce network weights while maintaining model performance. Motivated by the recent observation of emergent large magnitude features in Large Language Models (LLM) and MoE routing …