Dongmei Lu

Clinical characteristics and risk factors for prediction of severity in patients with COVID-19: a retrospective multicentre study

Maidina Abudouaini, Wenjuan Zeng, Shengtao Zeng, Bing Liu et autres

INTRODUCTION: This study aimed to investigate the clinical characteristics of patients infected with coronavirus disease 2019 (COVID-19) and to identify risk factors associated with severe infection among Chinese patients. METHODOLOGY: We collected demographic data, clinical characteristics, and laboratory test results at admission …

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Intermittent hypoxemia in preterm infants: Glial fibrillary acidic protein as a potential brain injury biomarker

Elie G. Abu Jawdeh, Linda J. Van Eldik, Xiao Xu, Philip M. Westgate et autres

INTRODUCTION: Intermittent hypoxemia (IH) frequently occurs in preterm infants and is increasingly linked to adverse outcomes. We previously demonstrated a relationship between IH and S100B, a brain injury biomarker. Here, we assess these relationships with glial fibrillary acidic protein (GFAP), a protein …

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Gut Microbiome Composition and Variance Are Modified by Degree of Growth Failure in Preterm Infants: A Prospective Study

Katherine A. Stumpf, Miranda Green, Xinying Niu, Dongmei Lu et autres

Background/Objectives: Preterm infants often require increased caloric intake to maintain appropriate growth while in the neonatal intensive care unit (NICU). Emerging evidence suggests that alterations of the gut microbiome may play a role in infant and childhood growth patterns. The fecal microbiome …

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Ivonescimab plus chemotherapy versus tislelizumab plus chemotherapy as first-line treatment for advanced squamous non-small-cell lung cancer (HARMONi-6): a randomised, double-blind, phase 3 trial

Zhiwei Chen, Fang Yang, Jiang Zhou, Longhua Sun et autres

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Causal Effect of Plasma Fatty Acid Profiles on Psoriasis Risk: Genetic Evidence from a Mendelian Randomization Study

Lei Yao, X.W. Wang, Dongmei Lu, Suyan Tian

Introduction: Emerging evidence indicates that omega-3 fatty acids from fish oil may serve as beneficial dietary supplements for psoriasis management. Clinical observations demonstrate a significant association between psoriasis improvement and increased docosahexaenoic acid (DHA) levels. However, the causal relationship between fatty acids …

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Cadonilimab in advanced cervical cancer: the COMPASSION-16 trial – Authors' reply

Ting Liu, Dongmei Lu, Xiaohua Wu

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Abstract CT011: Penpulimab versus placebo in combination with chemotherapy as first-line treatment for recurrent or metastatic nasopharyngeal carcinoma: A global, multicenter, randomized, double-blind, phase 3 trial (AK105-304)

Chaosu Hu, Xiaozhong Chen, Tingting Xu, Shuang Huang et autres

Abstract Background: Studies have shown that the combination of PD-1 inhibitors with chemotherapy exhibits promising efficacy as a first-line treatment for Asian patients with recurrent or metastatic nasopharyngeal carcinoma (R/M NPC). This presentation reports the results of a global phase 3 clinical …

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Author Correction: First-line cadonilimab plus chemotherapy in HER2-negative advanced gastric or gastroesophageal junction adenocarcinoma: a randomized, double-blind, phase 3 trial

Lin Shen, Yanqiao Zhang, Ziyu Li, Xiaotian Zhang et autres

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First-line cadonilimab plus chemotherapy in HER2-negative advanced gastric or gastroesophageal junction adenocarcinoma: a randomized, double-blind, phase 3 trial

Lin Shen, Yanqiao Zhang, Ziyu Li, Xiaotian Zhang et autres

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A Single-Center, Large-Sample Retrospective Study on the Etiological Spectrum and Risk Factors for Severe Pneumonia in Hospitalized Patients

Maidina Abudouaini, MA Jinquan, Dongmei Lu, See PDF

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Maternal high fat diet exposure modifies amniotic fluid metabolites and expands group 3 innate lymphoid cells dependent on the maternal microbiome and MyD88-signaling

Xinying Niu, Dongmei Lu, Sana Jaleel, Suzette N. Palmer et autres

Background Maternal high fat diet (mHFD) exposure expands IL-17 producing group 3 innate lymphoid cells (IL17+ve ILC3) in the small intestine of neonatal murine offspring and increases their susceptibility to intestinal inflammation. How mHFD modulates innate immunity in the fetal offspring remains …

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Author response for "Establishment of a Raman microsphere-based immunochromatographic method for the combined detection of influenza A and B viruses and SARS-CoV-2 antigen on a single T-line"

Aolin Zhu, Binbin Zhao, Jiutong Li, Xinxia Li et autres