Bora Shin

In vitro antimicrobial resistance properties of rifapentine and rifampicin are indistinguishable

Valeria Barcelli, Bora Shin, Barry Boon Liang Choo, Sarah Leela Dorett et autres

ABSTRACT Tuberculosis (TB) is a major global health threat, with millions of new cases diagnosed annually. Rifampicin is a cornerstone drug in the current standard of care for TB treatment. Recently, rifapentine, an analog of rifampicin, has been considered as an alternative …

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Metabolic signals regulate resuscitation speed of antibiotic persister bacteria during infection

Jeong Moo Han, J H Lee, Jiseon Kim, Yi Qing Lee et autres

Abstract All living organisms adjust their metabolism in response to environmental changes. Under unfavorable conditions, organisms enter a state of dormancy by halting metabolism, enabling survival. Dormant bacteria become highly tolerant to antibiotics-a phenomenon called persistence. Here, we demonstrate that selective metabolic …

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First record of Pieris nesis (Fruhstorfer, 1909) (Lepidoptera, Pieridae) from Korea

Sung‐Soo Kim, Bora Shin, Chang‐Gyu Park, Sumin Jo et autres

Six Lepidoptera for the fauna of Korea (Insecta: Lepidoptera)

Bora Shin, Sung‐Soo Kim, Jae-Young Lee, Sei‐Woong Choi

We report six moth species in six families (Lypusidae, Sesiidae, Zygaenidae, Pyralidae, Noctuidae, and Geometridae) that are unrecorded or doubtfully known from Korea. We provide taxonomic information, description, and figures of male and female genitalia if possible.

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A novel decoy strategy for polymyxin resistance in Acinetobacter baumannii

Jae-Eun Park, Mi-Sung Kim, Bora Shin, Mingyeong Kang et autres

Modification of the outer membrane charge by a polymyxin B (PMB)-induced PmrAB two-component system appears to be a dominant phenomenon in PMB-resistant Acinetobacter baumannii . PMB-resistant variants and many clinical isolates also appeared to produce outer membrane vesicles (OMVs). Genomic, transcriptomic, and …

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Author response: A novel decoy strategy for polymyxin resistance in Acinetobacter baumannii

Jae-Eun Park, Mi-Sung Kim, Bora Shin, Mingyeong Kang et autres

Outer membrane vesicles serve as decoys to reduce the chance of direct polymyxin B (PMB) binding to cells, which partly explains why many clinical isolates and microbial communities can be protected against PMB treatment.

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Dumulmycin, an Antitubercular Bicyclic Macrolide from a Riverine Sediment-Derived Streptomyces sp.

Joon Soo An, Bora Shin, Tae Ho Kim, Sunghoon Hwang et autres

Dumulmycin ( 1 ) was isolated from Streptomyces sp. DM28, a bacterial strain from a riverine sediment sample. The structure of 1 was elucidated as a bicyclic macrolide possessing 19-membered and 5-membered rings by spectroscopic analysis. The stereochemistry of 1 was determined …

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Erratum for Park et al., “Protective Role of Bacterial Alkanesulfonate Monooxygenase under Oxidative Stress”

Chulwoo Park, Bora Shin, Woojun Park

Volume 86, no. 15, e00692-20, 2020, [https://doi.org/10.1128/AEM.00692-20][1]. Page 1: The affiliation should appear as given in this Erratum. [1]: /lookup/doi/10.1128/AEM.00692-20

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Comparative genomics of wild-type and laboratory-evolved biofilm-overproducing Deinococcus metallilatus strains

Chulwoo Park, Bora Shin, Wonjae Kim, Hoon Cheong et autres

Deinococcus metallilatus MA1002 was exposed to ultraviolet radiation to generate mutants with enhanced biofilm production. Two strains (nos 5 and 6) were then selected based on their high biofilm formation, as well as their possession of higher concentrations of extracellular matrix components …

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Formicolides A and B, Antioxidative and Antiangiogenic 20-Membered Macrolides from a Wood Ant Gut Bacterium

Joon Soo An, Ji-Yun Lee, Eunji Kim, Hyungju Ahn et autres

Two new macrolides, formicolides A ( 1 ) and B ( 2 ), were isolated from Streptomyces sp. BA01, a gut bacterial strain of the wood ant ( Formica yessensis ). Their 20-membered macrocyclic lactone structures were established using NMR and mass …

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Formicins, N -Acetylcysteamine-Bearing Indenone Thioesters from a Wood Ant-Associated Bacterium

Young Eun Du, Woong Sub Byun, Seok Beom Lee, Sunghoon Hwang et autres

Formicins A–C ( 1 – 3 ) were discovered from Streptomyces sp. associated with wood ants. The structures of 1 and 2 were elucidated as indenone thioesters bearing N -acetylcysteamine based on spectroscopic analysis. The configurations of 1 – 3 were determined …

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Protective Role of Bacterial Alkanesulfonate Monooxygenase under Oxidative Stress

Chulwoo Park, Bora Shin, Woojun Park

ssuD and tauD , which play a role in the degradation of organosulfonate, were expressed during n -hexadecane metabolism and oxidative stress conditions in A. oleivorans DR1. Our study confirmed that hexadecanesulfonate was accidentally generated during bacterial n -hexadecane degradation in sulfate-limited …

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