Lin Zhou

Photodynamic immunotherapy of Ruthenium(II) polypyridyl complexes: Application in the treatment of colorectal Cancer

Lin Zhou, Huiyan Hu, Jiongbang Li, Yan Li Yang et autres

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SIRT2-dependent CPT1A deacetylation in macrophages inhibits periodontitis

Yixuan Jiang, Xiu Yao, Zhizhong Jiang, Xiaomeng Liu et autres

Introduction Periodontitis is intricately related to systemic disorders and exerts a negative impact on quality of life. Recent studies have suggested a potential association between periodontitis and fatty acid oxidation (FAO), a key metabolic process involved in energy production and cellular function. …

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Learning curve for electromagnetic navigation bronchoscopy-guided microwave ablation: a cumulative sum analysis

Yaochen Huang, Lin Zhou, Jianing Wang, Zhipeng Hao et autres

Background: Electromagnetic navigation bronchoscopy (ENB) transbronchial microwave ablation (MWA) has showed its potential in treating pulmonary nodules. However, the learning curve of this technique remains unclear. This study aimed to analyze the learning curve of ENB-guided MWA for treating pulmonary nodules. Methods: …

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Author response for "Improving outcomes in electromagnetic navigation bronchoscopy-guided transbronchial microwave ablation for pulmonary nodules: the role of cone-beam computed tomography"

Yaochen Huang, Lin Zhou, Jianing Wang, Zhipeng Hao et autres

Synthesis, characterization and studies of iridium (III) complexes inducing cell death via apoptosis and ferroptosis

Qiying Feng, Lin Zhou, Shuang Tian, Jiawan Yang et autres

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TNFAIP3 affects ferroptosis after traumatic brain injury by affecting the deubiquitination and ubiquitination pathways of the HMOX1 protein and ACSL3

Lin Zhou, Lei Li, Jinghao Yang, Maierdan Mansuer et autres

The occurrence and progression of traumatic brain injury involve a complex process. The pathophysiological mechanisms triggered by neuronal damage include various forms of programmed cell death, including ferroptosis. We observed upregulation of TNFAIP3 in mice after traumatic brain injury. Overexpression of TNFAIP3 …

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Induction of ferroptosis of iridium(III) complexes localizing at the mitochondria and lysosome by photodynamic therapy

Yajie Niu, Shuanghui Tang, Jiongbang Li, Chunxia Huang et autres

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A comprehensive review of immune checkpoint inhibitor-related diabetes mellitus: incidence, clinical features, management, and prognosis

Lin Zhou, Shuhui Yang, Youtao Li, Cheng Xue et autres

Immune checkpoint inhibitor-related diabetes mellitus (ICI-DM) is a rare complication that medical oncologists seldom encounter in routine practice. The sporadic nature and intrinsic complexity of ICI-DM make it challenging to analyze comprehensively in experimental settings. In this review, we examine phase 3 …

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Evaluation of Efficiency of Liposome-Entrapped Iridium(III) Complexes Inhibiting Tumor Growth In Vitro and In Vivo

Huiyan Hu, Jing Chen, Fan Zhang, Zhujun Sheng et autres

In this paper, three new iridium(III) complexes: [Ir(piq) 2 (DFIPP)]PF 6 (piq = deprotonated 1-phenylisoquinoline, DFIPP = 3,4-difluoro-2-(1 H -imidazo[4,5- f ][1,10]phenenthrolin-2-yl)phenol, 3a ), [Ir(bzq) 2 (DFIPP)]PF 6 (bzq = deprotonated benzo[ h ]quinoline, 3b ), and [Ir(ppy) 2 (DFIPP)]PF 6 (ppy …

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Assessing TGF-β Prognostic Model Predictions for Chemotherapy Response and Oncogenic Role of FKBP1A in Liver Cancer

Weimei Chen, Qinghe Que, Rongrong Zhong, Lin Zhou et autres

BACKGROUND: The Transforming Growth Factor-Beta (TGF-β) signaling pathway plays a crucial role in the pathogenesis of diseases. This study aimed to identify differentially expressed TGF-β-related genes in liver cancer patients and to correlate these findings with clinical features and immune signatures. METHODS: …

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Erianin induces ferroptosis in GSCs via REST/LRSAM1 mediated SLC40A1 ubiquitination to overcome TMZ resistance

Maierdan Mansuer, Lin Zhou, Chengbin Wang, Liang Gao et autres

In recent studies, erianin, a natural product isolated from Dendrobium chrysotoxum Lindl, has exhibited notable anticancer properties. Ferroptosis, a novel form of programmed cell death, holds potential as a strategy to overcome Temozolomide (TMZ) resistance in glioma by inducing ferroptosis in TMZ-resistant …

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White light increases anticancer effectiveness of iridium(III) complexes toward lung cancer A549 cells

Gechang Li, Jing Chen, Yufeng Xie, Yan Yang et autres

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