Zhijun Liu

Deep learning classifies cell death in cerebral ischemia reperfusion injury

Peng Zhang, Chenyang Xu, Zhijun Liu, Yadong Geng et autres

Cerebral ischemia–reperfusion injury (CIRI) is characterized by complex and overlapping cell death processes, including autophagy, apoptosis, and necrosis. Accurate discrimination among these cell death modalities is essential for pathological investigation, yet conventional pathological methods remain time-consuming and limited in precision. The present …

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Extracellular Vesicle‐Transferred ATP‐Citrate Lyase Induces Monocyte Differentiation Toward Tumor‐Associated Macrophages and Fuels Hepatocellular Carcinoma Progression

Zhijun Liu, Haihong Lai, Qing Yang, Chaoyue Zhang et autres

Tumor-associated macrophages (TAMs) arise from monocytes and represent major contributors to the immunosuppressive microenvironment of solid tumors. However, the environmental cues that govern TAM differentiation and immunosuppressive activity remain incompletely understood. Here we demonstrate that hepatocellular carcinoma (HCC) cells secrete extracellular vesicles …

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Independent and combined associations of dietary antioxidant exposure with all-cause and cause-specific mortality in the general population

Zhijun Liu, Zhuojian He, Yanfei Xing

This study aimed to determine if habitual intake of key dietary antioxidants, both individually and collectively, is associated with all-cause and cause-specific mortality among U.S. adults, given that oxidative stress heightens cardiovascular and cancer mortality risk. This prospective cohort study analysed 34,955 …

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Antibacterial Agent‐Loaded Hydrogels for Implant‐Associated Osteomyelitis: A Review

Bingcheng Ji, L Zhang, Zengchao Guo, Zhijun Liu

Implant-associated osteomyelitis (IAO) is a major clinical challenge due to persistent biofilms, antibiotic resistance, and impaired osteogenesis. Hydrogels, with tunable physicochemical properties, biocompatibility, and localized drug delivery capabilities, offer advanced solutions to these problems. This review systematically examines advanced hydrogel-based strategies for …

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Changes of mandibular organ, biosynthesis rate of methyl farnesoate, and their hemolymph levels during the ovarian development of the swimming crab Portunus trituberculatus

Meimei Liu, Zhijun Liu, Changkao Mu, Jianfeng Lu et autres

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Low-Molecular-Weight Heparin Plus Insulin in Hypertriglyceridemic Acute Pancreatitis

Wenhua He, Ling Ding, Zhijun Liu, Ming’e Hua et autres

Importance: Although insulin is widely used for early lipid lowering in hypertriglyceridemic acute pancreatitis, the clinical benefit of heparin combined with insulin remains unclear. Objective: To examine whether low-molecular-weight heparin (LMWH) combined with insulin is superior to insulin alone in improving clinical …

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Epidermal hydrodynamics controls water homeostasis of shoot meristems for plant adaptation to terrestrial environments

Yimin Zhu, Xianmiao Zhu, Simin Bi, Dan Teng et autres

Water uptake and redistribution represent a significant challenge for plant colonization of land. While vascular plants have evolved specialized structures for water transport, how water homeostasis is maintained in meristematic tissues remains elusive. Here, we show that the Arabidopsis shoot meristem develops …

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Taxifolin and Astilbin Protect Against Cadmium-Induced Oxidative Stress and Apoptosis in Chicken Liver Cells via Nrf2/HO-1 Signaling

Tiezhu Chen, Tianyu Han, Yusong Miao, Liangchun Yan et autres

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Undescribed Phenylpropanoid-Substituted Ester-Type Catechins from Green Tea Exert Antiaging Effects in Caenorhabditis elegans via Activating DAF-16, HSF-1, and Heat Shock Proteins

Zi Yang, Yuxing Zhang, Na Song, Chen‐Hui Chen et autres

Green tea processing creates a hot acidic environment that facilitates reactions between catechins and hydroxycinnamic acids (HCAs), generating new catechins. Accordingly, we developed a one-pot method incorporating a Michael addition reaction to synthesize 13 phenylpropanoid-substituted ester-type catechins (PSECs), whose contents exhibit seasonal …

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OsNIP3 ;1 mediates diurnal boron oscillation at rice vasculature tip

Meng‐Qi Wang, Yating Wang, Jia‐Shi Peng, Y. Yu et autres

Summary Plant apoplast represents an essential compartment for the proper function of certain mineral solutes, and vasculature acts as a long‐distance system to distribute them between different parts of the continuous apoplast. Guttation occurs at the distal end of the vasculature, but …

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The effect of alexithymia on depression: evidence from meta-analysis

Zhijun Liu, Shiwei He, Chunna Hou

Introduction: Depression is primarily characterized by persistent low mood and cognitive dysfunction, whereas whereas alexithymia refers to difficulties in cognitively processing emotions. Although alexithymia being recognized as a risk factor for depression, there is no clear scholarly consensus on its exact role. …

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Analysis of the prognostic efficacy of syndecan-1 for patients with ACLF and its functional role in liver regeneration

Yingli He, Xiaoli Zhang, Yichen Yao, Juan Li et autres

BACKGROUND: Acute-on-chronic liver failure (ACLF) is a syndrome characterized by systemic inflammation with a high short-term mortality rate. Syndecan-1 (SDC-1) can independently predict the 90-day mortality of patients with septic shock. However, the role of SDC-1 in ACLF remains unknown. METHODS: In …

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