Brian Yan

Glucagon-Like Peptide-1 Receptor Agonist Therapy Reduces Fibrosis-4 Index in Metabolic Dysfunction-Associated Steatotic Liver Disease

Jonathan Weng, Anderson Huang, Tamiru B. Berake, Sarah L. Chen et autres

Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a leading contributor to liver-related morbidity and mortality. Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have shown promise in improving MASLD-related outcomes, but their effect on hepatic fibrosis remains unclear. This study evaluated the impact …

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90 SHORT AND LONG-TERM OUTCOMES OF ENDOSCOPIC BALLOON DILATATION FOR NAÏVE AND ANASTOMOTIC CROHN’S DISEASE RELATED STRICTURES: A CANADIAN TERTIARY CENTER EXPERIENCE

Sudheer K. Vuyyuru, Gaurav Nigam, Shane Goodwin, Shivya Sethi et autres

90 SHORT AND LONG-TERM OUTCOMES OF ENDOSCOPIC BALLOON DILATATION FOR NAÏVE AND ANASTOMOTIC CROHN’S DISEASE RELATED STRICTURES: A CANADIAN TERTIARY CENTER EXPERIENCE

Sudheer K. Vuyyuru, Gaurav Nigam, Shane Goodwin, Shivya Sethi et autres

TWSG1 variation identifies a ustekinumab-response phenotype in patients with inflammatory bowel disease

Mohammed Alkhalifa, Gio Randon Dela Cruz, Terry Ponich, James C. Gregor et autres

OBJECTIVES: A genome-wide association study identified that genetic variation in the twisted gastrulation protein homolog-1 gene ( TWSG1 rs7242593) was linked to early clinical remission in ustekinumab-exposed patients in the UNITI clinical trials. We aimed to confirm if a single nucleotide variation …

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rhPTH(1-84) for hypoparathyroidism: a randomized study of patient-reported outcomes

Maria Luisa Brandi, Tamara Vokes, Natasha M. Appelman‐Dijkstra, Olulade Ayodele et autres

OBJECTIVE: To assess the impact of recombinant human parathyroid hormone (1-84) [rhPTH(1-84)] compared with placebo, in combination with conventional therapy with vitamin D and/or calcium supplements, on health-related quality of life (HRQoL) in patients with symptomatic chronic hypoparathyroidism (cHypoPT). DESIGN: Randomized, double-blind, …

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Mo2025: LONG-DURATION FLUCONAZOLE THERAPY MAY BE ASSOCIATED WITH FASTER TIME-TO-REMISSION IN PATIENTS WITH ACTIVE INFLAMMATORY BOWEL DISEASE (IBD)

Sarah Chen, Ahmed Fares, Brian Yan, Sonia Friedman et autres

Tu1900: DAY 3 OXFORD CRITERIA PREDICT STEROID NON-RESPONSE FOR ACUTE SEVERE ULCERATIVE COLITIS IN THE POST BIOLOGIC ERA: A 12-YEAR CANADIAN EXPERIENCE

Sudheer K. Vuyyuru, Lotus Alphonsus, Theshani Amalka De Silva, Virginia Solitano et autres

Su1622: UNHOUSED PATIENTS WITH ALCOHOL-ASSOCIATED LIVER DISEASE ARE ASSOCIATED WITH GREATER INCIDENCE OF COMPLICATIONS AND HOSPITAL-RELATED OUTCOMES

Ki Jung Lee, Gregory Fan, Sarah Chen, Tamiru B Berake et autres

Improving Multilingual ASR in the Wild Using Simple N-best Re-ranking

Brian Yan, Vineel Pratap, Shinji Watanabe, Michael Auli

Multilingual Automatic Speech Recognition (ASR) models are typically evaluated in a setting where the ground-truth language of the speech utterance is known, however, this is often not the case for most practical settings. Automatic Spoken Language Identification (SLID) models are not perfect …

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THE EFFECT OF ANTIFUNGAL THERAPY ON DISEASE ACTIVITY IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE: A RETROSPECTIVE MATCHED ANALYSIS

Sarah Chen, Ahmed Fares, Brian Yan, Sonia Friedman et autres

THE EFFECT OF ANTIFUNGAL THERAPY ON DISEASE ACTIVITY IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE: A RETROSPECTIVE MATCHED ANALYSIS

Sarah Chen, Ahmed Fares, Brian Yan, Sonia Friedman et autres

Abstract INTRODUCTION Fungal organisms have been implicated in disease activity in patients with inflammatory bowel disease (IBD). The effect of antifungal therapy on disease activity in IBD remains unclear. The purpose of our study was to (1) report indications for fluconazole use …

Adverse cardiovascular outcomes due to potential drug-drug interactions in statin therapy: a population-based study

A Lai, Kevin Ka‐Ho Kam, GuangMing Tan, Matthew Tam et autres

Abstract Background Statins have been proven to reduce morbidity and mortality in patients with known atherosclerotic cardiovascular disease (ASCVD) and in primary prevention. Given their unique role in ASCVD, concomitant use of statins and other medications are inevitable. Our clinicians’ duty is …

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