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Profil bibliographique

Jaeseon Lee

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

40Publications signalées
930Citations signalées
2Affiliations récentes

Les institutions déclarées

Les domaines associés

Systemic Lupus Erythematosus ResearchCytokine Signaling Pathways and InteractionsSalivary Gland Disorders and FunctionsRheumatoid Arthritis Research and TherapiesInflammasome and immune disorders

Les publications récentes

2025 conference-paper OpenAlex

Illy-Net: A GMM Based Performance Evaluation Framework for Sim-to-Real Transfer of RL Policies

Subin Im, Jaeseon Lee

Sim-to-Real transfer learning is a key approach for deploying reinforcement learning (RL) based control policies trained in simulation to real-world robotic environments. However, significant performance degradation often occurs due to the inherent physical discrepancies between simulation and reality, commonly referred to as …

kr (code pays fourni par la source)

0 citations
Accès ouvert 2025 article OpenAlex

Human nasal turbinate stem cells with specific gene signatures (HAS2, CXCL1, KRTAP1-5, GSTT2B, and C4B) attenuate rheumatoid arthritis

Jaeseon Lee, Hong Ki Min, Jung Yeon Lim, Young-Suk Song et autres

This study aimed to investigate the therapeutic effect of human nasal turbinate-derived stem cells (hNTSCs) on mice with rheumatoid arthritis (RA) and identify hNTSC gene signatures with therapeutic effects on RA. hNTSCs were obtained from 20 healthy controls (HCs) who had undergone …

kr, gb, us (code pays fourni par la source)

5 citations Scientific Reports
Accès ouvert 2024 article OpenAlex

Salivary gland organoid transplantation as a therapeutic option for radiation-induced xerostomia

Seong Gyeong Jeon, Jaeseon Lee, Su Jeong Lee, Jae‐Hwi Seo et autres

BACKGROUND: Xerostomia is a pathological condition characterized by decreased salivation due to salivary gland dysfunction and is frequently attributed to irreversible damage as a side effect of radiation therapy. Stem cell-derived organoid therapy has garnered attention as a promising avenue for resolving …

kr, vn (code pays fourni par la source)

22 citations Stem Cell Research & Therapy
Accès ouvert 2021 article OpenAlex

IL-17 and CCR9+α4β7– Th17 Cells Promote Salivary Gland Inflammation, Dysfunction, and Cell Death in Sjögren’s Syndrome

Sun‐Hee Hwang, Jin Seok Woo, Jeonghyeon Moon, SeungCheon Yang et autres

Previous studies have evaluated the roles of T and B cells in the pathogenesis of Sjögren's syndrome (SS); however, their relationships with age-dependent and metabolic abnormalities remain unclear. We examined the impacts of changes associated with aging or metabolic abnormalities on populations …

kr (code pays fourni par la source)

31 citations Frontiers in Immunology
Accès ouvert 2021 article OpenAlex

Baricitinib Attenuates Autoimmune Phenotype and Podocyte Injury in a Murine Model of Systemic Lupus Erythematosus

Jaeseon Lee, Youngjae Park, Se Gwang Jang, Seung-Min Hong et autres

Objective Baricitinib, a selective inhibitor for janus kinase (JAK) 1 and JAK2, is approved for use in rheumatoid arthritis. Systemic lupus erythematosus (SLE) is recently regarded as a potential candidate targeted by JAK inhibitors because of the relationship between its pathogenesis and …

kr (code pays fourni par la source)

43 citations Frontiers in Immunology
Accès ouvert 2021 article OpenAlex

Niclosamide suppresses the expansion of follicular helper T cells and alleviates disease severity in two murine models of lupus via STAT3

Se Gwang Jang, Jaeseon Lee, Seung-Min Hong, Youngseok Song et autres

Abstract Background Autoantibody production against endogenous cellular components is pathogenic feature of systemic lupus erythematosus (SLE). Follicular helper T (T FH ) cells aid in B cell differentiation into autoantibody-producing plasma cells (PCs). The IL-6 and IL-21 cytokine-mediated STAT3 signaling are crucial …

kr (code pays fourni par la source)

19 citations Journal of Translational Medicine
Accès ouvert 2020 article OpenAlex

Red ginseng extracts as an adjunctive therapeutic for gout: preclinical and clinical evidence

Jennifer Jooha Lee, Seung-Min Hong, Narae Park, Jaeseon Lee et autres

We investigated if Red ginseng extract (RGE) suppressed monosodium urate crystal (MSU)-induced NLRP3 activation and could be a potential therapeutic agent for gout. The effects of RGE on acute gouty inflammation were investigated using the air-pouch model. RGE significantly suppressed acute gout …

kr, us (code pays fourni par la source)

4 citations Food and Agricultural Immunology

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