Jan Eliáš

Beta2* Nicotinic Receptors Regulate Exploratory and Social Behavior Through Functionally Distinct Neuronal Populations

Helena Janíčková, Alice Abbondanza, Jan Eliáš, Chandani Verma et autres

cz (code pays fourni par la source)

Multistep allelic conversion in mouse pre-implantation embryos by AAV vectors

Petr Nickl, Irena Jenickova, Jan Eliáš, Petr Kašpárek et autres

Site-specific recombinases (SSRs) are critical for achieving precise spatiotemporal control of engineered alleles. These enzymes play a key role in facilitating the deletion or inversion of loci flanked by recombination sites, resulting in the activation or repression of endogenous genes, selection markers …

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Multistep allelic conversion in mouse pre-implantation embryos by AAV vectors

Petr Nickl, Irena Jenickova, Jan Eliáš, Petr Kašpárek et autres

ru, cz (code pays fourni par la source)

The role of the Bemisia tabaci and Trialeurodes vaporariorum cytochrome-P450 clade CYP6DPx in resistance to nicotine and neonicotinoids

Adam Pym, Bartlomiej J. Troczka, Angela Hayward, Bin Zeng et autres

The alkaloid, nicotine, produced by tobacco and other Solanaceae as an anti-herbivore defence chemical is one of the most toxic natural insecticides in nature. However, some insects, such as the whitefly species, Trialeurodes vaporariorum and Bemisia tabaci show strong tolerance to this …

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Overexpression of the UDP-glycosyltransferase UGT34A23 confers resistance to the diamide insecticide chlorantraniliprole in the tomato leafminer, Tuta absoluta

Charles E. Grant, Kumar Saurabh Singh, Angela Hayward, Benjamin J. Hunt et autres

The tomato leafminer, Tuta absoluta, is an invasive crop pest that has evolved resistance to many of the insecticides used for its control. To facilitate the investigation of the underpinning mechanisms of resistance in this species we generated a contiguous genome assembly …

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A single point mutation in the Bemisia tabaci cytochrome-P450 CYP6CM1 causes enhanced resistance to neonicotinoids

Adam Pym, John G. Mina, Bartlomiej J. Troczka, Angela Hayward et autres

The tobacco whitefly, Bemisia tabaci, is a polyphagous crop pest which causes high levels of economic damage across the globe. Insecticides are often required for the effective control of this species, among which the neonicotinoid class have been particularly widely used. Deciphering …

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Uncovering the OXPHOS complexes' interdependence mechanism

Kristýna Čunátová, Marek Vrbacký, Guillermo Puertas-Frias, Jan Eliáš et autres

cz (code pays fourni par la source)

Searching for function of TMEM70, TMEM242 and c15orf61 – recently identified interactors of subunit c from mammalian FoF1 ATP synthase

Aleksandra Pavlović Marković, Marek Vrbacký, Petr Pecina, Jan Eliáš et autres

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Correction to “Structural Biology-Guided Design, Synthesis, and Biological Evaluation of Novel Insect Nicotinic Acetylcholine Receptor Orthosteric Modulators”

Mark Montgomery, Stefano Rendine, Christoph T. Zimmer, Jan Eliáš et autres

ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionNEXTORIGINAL ARTICLEThis notice is a correctionCorrection to "Structural Biology-Guided Design, Synthesis, and Biological Evaluation of Novel Insect Nicotinic Acetylcholine Receptor Orthosteric Modulators"Mark MontgomeryMark MontgomeryMore by Mark Montgomery, Stefano RendineStefano RendineMore by Stefano Rendine, Christoph T. ZimmerChristoph T. ZimmerMore by …

Structural Biology-Guided Design, Synthesis, and Biological Evaluation of Novel Insect Nicotinic Acetylcholine Receptor Orthosteric Modulators

Mark Montgomery, Stefano Rendine, Christoph T. Zimmer, Jan Eliáš et autres

The development of novel and safe insecticides remains an important need for a growing world population to protect crops and animal and human health. New chemotypes modulating the insect nicotinic acetylcholine receptors have been recently brought to the agricultural market, yet with …

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Biogenesis, structure and physiological functions of mitochondrial ATP synthase

Jan Eliáš

Mammalian mitochondrial ATP synthase is an enzyme composed of 18 protein subunits, which is localised in the inner mitochondrial membrane. Its main function is to utilise proton gradient, produced by respiratory chain complexes (RCC), for the synthesis of ATP. Aside from the …

Efficient allele conversion in mouse zygotes and primary cells based on electroporation of Cre protein

Irena Jenickova, Petr Kašpárek, Silvia Petrezsélyová, Jan Eliáš et autres

cz (code pays fourni par la source)