Accès ouvert
2025
article
OpenAlex
Sergio Quesada‐Vázquez, M. Almagro, Gloria Cifuentes-Orjuela, Anna Antolín et autres
Background/Objectives. Preterm birth (PTB), affecting approximately 11.1% of pregnancies globally, often results from inflammation at the maternal–fetal interface triggered by microbial or immune dysregulation. This study investigates the efficacy of cell-free supernatant derived from Bifidobacterium longum subsp. infantis CECT 7210 and Lacticaseibacillus …
es
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Accès ouvert
2025
article
OpenAlex
Thomas Grüter, Carles Gaig, Yvette S. Crijnen, Maarten J. Titulaer et autres
Importance: Anti-IgLON5 disease is an autoimmune encephalopathy that often leads to severe disability or death. The efficacy of immunotherapy remains unknown. Objective: To investigate whether early immunotherapy is associated with disability and death in anti-IgLON5 disease. Design, Setting, and Participants: This retrospective, …
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Accès ouvert
2024
article
OpenAlex
Laia Ferreres-Serafini, Susana M. Martín–Orúe, Meritxell Sadurní, Jesús Jiménez et autres
) (OPN); and CTR + SYN + OPN (CON). Daily records including feed intake, body weight, and clinical signs, were maintained throughout the 15-day trial. At the end of the study samples from blood, digestive content, and gut tissues were collected to …
es
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Accès ouvert
2023
article
OpenAlex
Estefanía Diéguez, Ana Nieto-Ruíz, Natalia Sepúlveda-Valbuena, Florian Herrmann et autres
There is scarce evidence about early nutrition programming of dynamic aspects of glucose homeostasis. We analyzed the long-term effects of early nutrition on glycemic variability in healthy children. A total of 92 children participating in the COGNIS study were considered for this …
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Accès ouvert
2022
article
OpenAlex
Estefanía Diéguez, Ana Nieto-Ruíz, Cristina Martín-Pérez, Natalia Sepúlveda-Valbuena et autres
Breastfeeding (BF) is the gold standard in infant nutrition; knowing how it influences brain connectivity would help understand the mechanisms involved, which would help close the nutritional gap between infant formulas and breast milk. We analyzed potential long-term differences depending on the …
es, co
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Accès ouvert
2022
article
OpenAlex
Tomás Cerdó, Alicia Ruíz, Inmaculada Acuña, Ana Nieto-Ruíz et autres
BACKGROUND & AIMS: The critical window of concurrent developmental paths of the nervous system and gut microbiota in infancy provides an opportunity for nutritional interventions with potential health benefits later in life. METHODS: We compared the dynamics of gut microbiota maturation and …
es
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Accès ouvert
2022
article
OpenAlex
Ana Nieto-Ruíz, José Antonio García-Santos, Juan Verdejo‐Román, Estefanía Diéguez et autres
Background: Adequate nutrient intake during the first few months of life plays a critical role on brain structure and function development. Objectives: To analyze the long-term effects of an experimental infant formula (EF) on neurocognitive function and brain structure in healthy children …
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Accès ouvert
2021
article
OpenAlex
Florian Herrmann, Ana Nieto-Ruíz, Natalia Sepúlveda-Valbuena, Estefanía Diéguez et autres
Functional nutrients like synbiotics or milk-fat globule membrane (MFGM) affect positively host immunity, modifying intestinal microbioma and reducing early childhood infections. We compared effects of an experimental enriched-infant formula with long chain polyunsaturated fatty acids, MFGM, synbiotics, sialic acid, nucleotides and gangliosides …
es, co
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Accès ouvert
2020
article
OpenAlex
Ana Nieto-Ruíz, Estefanía Diéguez, Natalia Sepúlveda-Valbuena, Florian Herrmann et autres
Although early life nutrition influences brain development and mental health, the long-term effects of supplemented infant formula on children´s behavior remain unclear. We analyzed the effects of a bioactive nutrients-enriched-infant formula on children’s behavior up to 2.5 years, compared to a standard …
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Accès ouvert
2020
article
OpenAlex
Lorena Ruíz, Ana Belén Flórez, Borja Sánchez, José Antonio Moreno-Muñoz et autres
Certain non-digestible oligosaccharides (NDO) are specifically fermented by bifidobacteria along the human gastrointestinal tract, selectively favoring their growth and the production of health-promoting metabolites. In the present study, the ability of the probiotic strain Bifidobacterium longum subsp. infantis CECT7210 (herein referred to …
es
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Accès ouvert
2020
article
OpenAlex
Vincenzo Fierro, Rocco Luigi Valluzzi, Claudia Banzato, Ma A. Plaza et autres
OBJECTIVES: Infants with cow's milk allergy (CMA) are in need of a substitute formula up to 2 years. The are three requisites for a substitute of milk in CMA: tolerability, nutritional adequacy, and cost-effectiveness. We evaluate here the tolerability of a new …
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Accès ouvert
2020
article
OpenAlex
Ana Nieto-Ruíz, Estefanía Diéguez, Natalia Sepúlveda-Valbuena, Elvira Catena et autres
Nutrition during early life is essential for brain development and establishes the basis for cognitive and language skills development. It is well established that breastfeeding, compared to formula feeding, has been traditionally associated with increased neurodevelopmental scores up to early adulthood. We …
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