Yanwei Li

Based on the PINK1/Parkin signaling pathway, the protective effect of salidroside on cerebral ischemia-reperfusion injury in male rats was investigated

Yanwei Li, Jun Jie Tan

OBJECTIVE: Based on the male Sprague-Dawley rats middle cerebral artery occlusion model and SH-SY5Y hypoxia-reoxygenation model, this study systematically evaluated the neuroprotective effect of salidroside (SAL) on cerebral ischemia/reperfusion injury in rats, and explored its possible protective mechanism through PINK1/Parkin signaling axis …

cn (code pays fourni par la source)

Identification of 5mC regulatory factors mediating methylation patterns and prognosis models in head and neck squamous cell carcinoma

Yanwei Li, Yun‐Feng Cao, Nuerbiyamu Maimaitiyiming, Yue Li

BACKGROUND: This study explores the role of 5mC regulatory genes in head and neck squamous cell carcinoma (HNSCC), focusing on their association with tumor progression, metastasis, and prognosis. A prognostic model was also developed to predict patient survival. MATERIALS AND METHODS: Using …

cn (code pays fourni par la source)

A phase II exploratory study (NCT06208826) on maintenance immunotherapy in patients with resectable locally advanced head and neck cancer who achieved MPR after neoadjuvant immunotherapy combined with chemotherapy.

Hongling Wang, Xudong Wang, Yanwei Li, Peiguo Wang et autres

e18083 Background: Induction chemotherapy could improve functional preservation but could not provide long-term survival benefits in head and neck squamous cell carcinoma (HNSCC). Immunotherapy has achieved great success in the salvage treatment of recurrence and metastasis HNSCC. Many clinical studies have found …

cn (code pays fourni par la source)

Targeting BMPER as a therapeutic strategy for pulmonary arterial hypertension

Lina Shan, Xiaofeng Tang, Yi Liu, Weiyi Qi et autres

cn (code pays fourni par la source)

Aumolertinib plus chemotherapy as first-line treatment for advanced NSCLC with EGFR exon 19 deletion or exon 21 L858R: a phase II trial

Yanwei Li, Chenguang Li, Chenguang Li, Xiaoliang Zhao et autres

BACKGROUND: To evaluate the efficacy and safety of aumolertinib combined with pemetrexed and carboplatin as first-line treatment in advanced non-small-cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutation (exon 19 deletion or exon 21 L858R). METHODS: In phase II …

cn, us (code pays fourni par la source)

Acupuncture Dosage and Its Correlation with Effectiveness in Patients with Chronic Stable Angina: A Systematic Review and Meta-Analysis of Randomized Controlled Trial

Yanwei Li, Xiaoyan Zheng, Jinming Hu, Yongjun Yin et autres

Objective: This systematic review aimed to compare the efficacy of various acupuncture dosages for Chronic Stable Angina (CSA) using randomized controlled trials (RCTs), addressing the unclear relationship between dosage and effectiveness despite acupuncture’s potential. Methods: We searched eight bibliographic databases from inception …

cn (code pays fourni par la source)

Systematic Analysis of Molecular Subtypes and Immune Prediction Based on CD8 T Cell Pattern Genes Based on Head and Neck Cancer

Yanwei Li, Feng He, Shuang Liu, Zhanyu Pan

CD8+ T lymphocytes, also known as cytotoxic T lymphocytes, are the most powerful antitumour cells in the human body. Patients with head and neck squamous cell carcinoma (HNSCC) in whom CD8+ T lymphocyte infiltration is high have a better prognosis. However, the …

cn (code pays fourni par la source)

Apatinib and Ginsenoside-Rb1 Synergetically Control the Growth of Hypopharyngeal Carcinoma Cells

Yanwei Li, Feng He, Yu Zhang, Zhanyu Pan

Background. Apatinib is an anticancer drug known to inhibit the vascular endothelial growth factor receptor-2 (VEGFR-2) through regulating tyrosine kinases. Drug resistance and reduced activity in various cancers is the matter of great concern; thus, researchers opt to use combination of the …

cn (code pays fourni par la source)